Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats
Starckx, Sofie, Batheja, Ameesha, Verheyen, Geert R, Jonghe, Sandra De, Steemans, Kristel, Dijck, Bram Van, Singer, Monica, Bogdan, Nancy, Snoeys, Jan, Vinken, Petra, Sasaki, Jennifer C, Gompel, Jacky Van, Guzzie-Peck, Peggy, Lampo, Ann, Lammens, Lieve
Published in Toxicologic pathology (01.07.2013)
Published in Toxicologic pathology (01.07.2013)
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Journal Article
Liver Monocytes and Kupffer Cells Remain Transcriptionally Distinct during Chronic Viral Infection
van de Garde, Martijn D B, Movita, Dowty, van der Heide, Marieke, Herschke, Florence, De Jonghe, Sandra, Gama, Lucio, Boonstra, Andre, Vanwolleghem, Thomas
Published in PloS one (03.11.2016)
Published in PloS one (03.11.2016)
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The Biodistribution of the Spike Protein after Ad26.COV2.S Vaccination Is Unlikely to Play a Role in Vaccine-Induced Immune Thrombotic Thrombocytopenia
Marquez-Martinez, Sonia, Khan, Selina, Lubbe, Joan van der, Solforosi, Laura, Costes, Lea M M, Choi, Ying, Boedhoe, Satish, Verslegers, Mieke, Heerden, Marjolein van, Roosen, Wendy, Jonghe, Sandra De, Kristyanto, Hendy, Rezelj, Veronica, Hendriks, Jenny, Serroyen, Jan, Tolboom, Jeroen, Wegmann, Frank, Zahn, Roland C
Published in Vaccines (Basel) (01.05.2024)
Published in Vaccines (Basel) (01.05.2024)
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Journal Article
Carcinogenicity in rats of the SGLT2 inhibitor canagliflozin
De Jonghe, Sandra, Proctor, Jim, Vinken, Petra, Feyen, Bianca, Wynant, Inneke, Marien, Dirk, Geys, Helena, Mamidi, Rao N.V.S., Johnson, Mark D.
Published in Chemico-biological interactions (05.12.2014)
Published in Chemico-biological interactions (05.12.2014)
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Journal Article
An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines
Sistare, Frank D, Morton, Daniel, Alden, Carl, Christensen, Joel, Keller, Douglas, Jonghe, Sandra De, Storer, Richard D, Reddy, M Vijayaraj, Kraynak, Andrew, Trela, Bruce, Bienvenu, Jean-Guy, Bjurström, Sivert, Bosmans, Vanessa, Brewster, David, Colman, Karyn, Dominick, Mark, Evans, John, Hailey, James R, Kinter, Lewis, Liu, Matt, Mahrt, Charles, Marien, Dirk, Myer, James, Perry, Richard, Potenta, Daniel, Roth, Arthur, Sherratt, Philip, Singer, Thomas, Slim, Rabih, Soper, Keith, Fransson-Steen, Ronny, Stoltz, James, Turner, Oliver, Turnquist, Susan, van Heerden, Marjolein, Woicke, Jochen, DeGeorge, Joseph J
Published in Toxicologic pathology (01.06.2011)
Published in Toxicologic pathology (01.06.2011)
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Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model
Ispas, Gabriela, Koul, Anil, Verbeeck, Johan, Sheehan, Jennifer, Sanders-Beer, Brigitte, Roymans, Dirk, Andries, Koen, Rouan, Marie-Claude, De Jonghe, Sandra, Bonfanti, Jean-François, Vanstockem, Marc, Simmen, Kenneth, Verloes, Rene
Published in PloS one (26.05.2015)
Published in PloS one (26.05.2015)
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Intravenous Administration of Ad26.COV2.S Does Not Induce Thrombocytopenia or Thrombotic Events or Affect SARS-CoV-2 Spike Protein Bioavailability in Blood Compared with Intramuscular Vaccination in Rabbits
Khan, Selina, Marquez-Martinez, Sonia, Erkens, Tim, de Wilde, Adriaan, Costes, Lea M M, Vinken, Petra, De Jonghe, Sandra, Roosen, Wendy, Talia, Chiara, Chamanza, Ronnie, Serroyen, Jan, Tolboom, Jeroen, Zahn, Roland C, Wegmann, Frank
Published in Vaccines (Basel) (30.11.2023)
Published in Vaccines (Basel) (30.11.2023)
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JNJ-64794964 (AL-034/TQ-A3334), a TLR7 agonist, induces sustained anti-HBV activity in AAV/HBV mice via non-cytolytic mechanisms
Herschke, Florence, Li, Chris, Zhu, Ren, Han, Qinglin, Wu, Qun, Lu, Qing, Barale-Thomas, Erio, De Jonghe, Sandra, Lin, Tse-I., De Creus, An
Published in Antiviral research (01.12.2021)
Published in Antiviral research (01.12.2021)
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Species differences in small intestinal exposure-related epithelial vacuolation in rats and dogs treated with a heteroaryldihydropyrimidine molecule
Dai, Jieyu, Chen, Tao, Meng, Ryan, Jardi, Ferran, Kourula, Stephanie, Pham, Ly, De Jonghe, Sandra, De Smedt, Ann, Frisk, Anna-Lena, Xie, Jianxun
Published in Journal of applied toxicology (01.03.2024)
Published in Journal of applied toxicology (01.03.2024)
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Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic doses
Zhou, Junguo, De Jonghe, Sandra, Codd, Ellen E., Weiner, Sandy, Gallacher, David, Stahle, Paul, Kelley, Michael F., Kuffner, Edwin K., Flores, Christopher M., Eichenbaum, Gary E.
Published in Regulatory toxicology and pharmacology (04.01.2023)
Published in Regulatory toxicology and pharmacology (04.01.2023)
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Modeling the Time Course of the Tissue Responses to Intramuscular Long-acting Paliperidone Palmitate Nano-/Microcrystals and Polystyrene Microspheres in the Rat
Darville, Nicolas, van Heerden, Marjolein, Erkens, Tim, De Jonghe, Sandra, Vynckier, An, De Meulder, Marc, Vermeulen, An, Sterkens, Patrick, Annaert, Pieter, Van den Mooter, Guy
Published in Toxicologic pathology (01.02.2016)
Published in Toxicologic pathology (01.02.2016)
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The effect of macrophage and angiogenesis inhibition on the drug release and absorption from an intramuscular sustained-release paliperidone palmitate suspension
Darville, Nicolas, van Heerden, Marjolein, Mariën, Dirk, De Meulder, Marc, Rossenu, Stefaan, Vermeulen, An, Vynckier, An, De Jonghe, Sandra, Sterkens, Patrick, Annaert, Pieter, Van den Mooter, Guy
Published in Journal of controlled release (28.05.2016)
Published in Journal of controlled release (28.05.2016)
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Journal Article
Opinion on Maintaining In-House GLP Status for Toxicologic Pathology in Pharmaceutical and (Agro)Chemical Development
Gauthier, Béatrice E, Bach, Ute, Chanut, Franck, De Jonghe, Sandra, Groeters, Sibylle, Mueller, Gundi, Palazzi, Xavier, Pohlmeyer-Esch, Gabriele, Rinke, Matthias, Schorsch, Frédéric
Published in Toxicologic pathology (01.01.2022)
Published in Toxicologic pathology (01.01.2022)
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Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct
Movita, Dowty, van de Garde, Martijn D B, Biesta, Paula, Kreefft, Kim, Haagmans, Bart, Zuniga, Elina, Herschke, Florence, De Jonghe, Sandra, Janssen, Harry L A, Gama, Lucio, Boonstra, Andre, Vanwolleghem, Thomas
Published in Journal of virology (01.05.2015)
Published in Journal of virology (01.05.2015)
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Journal Article
Timing is everything for sperm assessment in fertility studies
Mariën, Dirk, Bailey, Graham P., Eichenbaum, Gary, De Jonghe, Sandra
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2016)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2016)
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Journal Article
Dose- and Time-dependency of the Toxicity and Pharmacokinetic Profiles of Bedaquiline and Its N-desmethyl Metabolite in Dogs
Smyej, Ilham, De Jonghe, Sandra, Looszova, Adriana, Mannens, Geert, Verhaeghe, Tom, Thijssen, Sandy, Starckx, Sofie, Lampo, Ann, Rouan, Marie-Claude
Published in Toxicologic pathology (01.07.2017)
Published in Toxicologic pathology (01.07.2017)
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Testing of acetaminophen in support of the international multilaboratory in vivo rat Pig‐a assay validation trial
van der Leede, Bas‐jan, Weiner, Sandy, Van Doninck, Terry, De Vlieger, Kathleen, Schuermans, Ann, Tekle, Fetene, Geys, Helena, van Heerden, Marjolein, De Jonghe, Sandra, Van Gompel, Jacky
Published in Environmental and molecular mutagenesis (01.06.2020)
Published in Environmental and molecular mutagenesis (01.06.2020)
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Renal tubular and adrenal medullary tumors in the 2-year rat study with canagliflozin confirmed to be secondary to carbohydrate (glucose) malabsorption in the 15-month mechanistic rat study
De Jonghe, Sandra, Johnson, Mark D., Mamidi, Rao N.V.S., Vinken, Petra, Feyen, Bianca, Lammens, Godelieve, Proctor, Jim
Published in Chemico-biological interactions (01.11.2017)
Published in Chemico-biological interactions (01.11.2017)
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Journal Article
“All pigs are equal” Does the background data from juvenile Göttingen minipigs support this?
Feyen, Bianca, Penard, Laure, van Heerden, Marjolein, Fant, Pierluigi, Marsden, Edward, De Jonghe, Sandra, Desmidt, Maria, Mousa, Sien Maki, Bailey, Graham Paul
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2016)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2016)
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