Tie2 protects the vasculature against thrombus formation in systemic inflammation
Higgins, Sarah J, De Ceunynck, Karen, Kellum, John A, Chen, Xiuying, Gu, Xuesong, Chaudhry, Sharjeel A, Schulman, Sol, Libermann, Towia A, Lu, Shulin, Shapiro, Nathan I, Christiani, David C, Flaumenhaft, Robert, Parikh, Samir M
Published in The Journal of clinical investigation (01.04.2018)
Published in The Journal of clinical investigation (01.04.2018)
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Journal Article
Local Elongation of Endothelial Cell-anchored von Willebrand Factor Strings Precedes ADAMTS13 Protein-mediated Proteolysis
De Ceunynck, Karen, Rocha, Susana, Feys, Hendrik B., De Meyer, Simon F., Uji-i, Hiroshi, Deckmyn, Hans, Hofkens, Johan, Vanhoorelbeke, Karen
Published in The Journal of biological chemistry (21.10.2011)
Published in The Journal of biological chemistry (21.10.2011)
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Journal Article
Targeting PAR1: Now What?
Flaumenhaft, Robert, De Ceunynck, Karen
Published in Trends in pharmacological sciences (Regular ed.) (01.08.2017)
Published in Trends in pharmacological sciences (Regular ed.) (01.08.2017)
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Journal Article
Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics
Jain, A, Barrile, R, van der Meer, A D, Mammoto, A, Mammoto, T, De Ceunynck, K, Aisiku, O, Otieno, M A, Louden, C S, Hamilton, G A, Flaumenhaft, R, Ingber, D E
Published in Clinical pharmacology and therapeutics (01.02.2018)
Published in Clinical pharmacology and therapeutics (01.02.2018)
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Journal Article
PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury
De Ceunynck, Karen, Peters, Christian G., Jain, Abhishek, Higgins, Sarah J., Aisiku, Omozuanvbo, Fitch-Tewfik, Jennifer L., Chaudhry, Sharjeel A., Dockendorff, Chris, Parikh, Samir M., Ingber, Donald E., Flaumenhaft, Robert
Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2018)
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Journal Article
The Secreted Tyrosine Kinase Vlk Is Essential for Normal Platelet Activation and Thrombus Formation
Revollo, Leila, Merrill-Skoloff, Glenn, De Ceunynck, Karen, Dilks, James, Bordoli, Mattia, Peters, Christian, Noetzli, Leila, Ionescu, Andreia, Rosen, Vicki, Italiano, Joseph E., Whitman, Malcolm, Flaumenhaft, Robert
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar
Aisiku, Omozuanvbo, Peters, Christian G., De Ceunynck, Karen, Ghosh, Chandra C., Dilks, James R., Fustolo-Gunnink, Susanna F., Huang, Mingdong, Dockendorff, Chris, Parikh, Samir M., Flaumenhaft, Robert
Published in Blood (19.03.2015)
Published in Blood (19.03.2015)
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Journal Article
The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation
Revollo, Leila, Merrill-Skoloff, Glenn, De Ceunynck, Karen, Dilks, James R., Guo, Shihui, Bordoli, Mattia R., Peters, Christian G., Noetzli, Leila, Ionescu, Andreia, Rosen, Vicki, Italiano, Joseph E., Whitman, Malcolm, Flaumenhaft, Robert
Published in Blood (06.01.2022)
Published in Blood (06.01.2022)
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Journal Article
Dysfunctional Endothelium Drives a Pre-DIC State in Endotoxemia
De Ceunynck, Karen E.P., Higgins, Sarah J., Chaudhry, Sharjeel A., Parikh, Samir, Flaumenhaft, Robert C.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation
Bekendam, R. H., Iyu, D., Passam, F., Stopa, J. D., De Ceunynck, K., Muse, O., Bendapudi, P. K., Garnier, C. L., Gopal, S., Crescence, L., Chiu, J., Furie, B., Panicot‐Dubois, L., Hogg, P. J., Dubois, C., Flaumenhaft, R.
Published in Journal of thrombosis and haemostasis (01.11.2018)
Published in Journal of thrombosis and haemostasis (01.11.2018)
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Journal Article
Shear-Stress-Induced Conformational Changes of von Willebrand Factor in a Water–Glycerol Mixture Observed with Single Molecule Microscopy
Vergauwe, Robrecht M. A, Uji-i, Hiroshi, De Ceunynck, Karen, Vermant, Jan, Vanhoorelbeke, Karen, Hofkens, Johan
Published in The journal of physical chemistry. B (29.05.2014)
Published in The journal of physical chemistry. B (29.05.2014)
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Journal Article
A Chemical APC Mimetic Protects Endothelium from Thromboinflammatory Injury
De Ceunynck, Karen E.P., Peters, Christian G., Chaudhry, Sharjeel A., Jain, Abhishek, Higgins, Sarah J., Aisiku, Omozuanvbo, Fitch-Tewfik, Jennifer, Dockendorff, Christopher, Parikh, Samir, Ingber, Donald E., Flaumenhaft, Robert C.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Single Particle Tracking of ADAMTS13 (A Disintegrin and Metalloprotease with Thrombospondin Type-1 Repeats) Molecules on Endothelial von Willebrand Factor Strings
De Ceunynck, Karen, Rocha, Susana, De Meyer, Simon F., Sadler, J.Evan, Uji-i, Hiroshi, Deckmyn, Hans, Hofkens, Johan, Vanhoorelbeke, Karen
Published in The Journal of biological chemistry (28.03.2014)
Published in The Journal of biological chemistry (28.03.2014)
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Journal Article
The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation
Revollo, Leila, Merrill-Skoloff, Glenn, De Ceunynck, Karen, Dilks, James R, Bordoli, Mattia, Peters, Christian G, Noetzli, Leila, Ionescu, Andreia, Rosen, Vicki, Italiano, Joseph E, Whitman, Malcolm, Flaumenhaft, Robert
Published in bioRxiv (26.01.2021)
Published in bioRxiv (26.01.2021)
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Paper
SCAFFOLD MATRIX ATTACHMENT REGIONS FOR GENE THERAPY
MUSKAVITCH, Marc A. T, KOIRALA, Adarsha, PACHECO-GARCIA, Almudena, DE CEUNYNCK, Karen Ellen Petra
Year of Publication 20.07.2023
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Year of Publication 20.07.2023
Patent
SCAFFOLD MATRIX ATTACHMENT REGIONS FOR GENE THERAPY
MUSKAVITCH, Marc A. T, KOIRALA, Adarsha, PACHECO-GARCIA, Almudena, DE CEUNYNCK, Karen Ellen Petra
Year of Publication 09.02.2023
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Year of Publication 09.02.2023
Patent