Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer
Yang, Xiaojing, Han, Han, De Carvalho, Daniel D., Lay, Fides D., Jones, Peter A., Liang, Gangning
Published in Cancer cell (13.10.2014)
Published in Cancer cell (13.10.2014)
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DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
Roulois, David, Loo Yau, Helen, Singhania, Rajat, Wang, Yadong, Danesh, Arnavaz, Shen, Shu Yi, Han, Han, Liang, Gangning, Jones, Peter A., Pugh, Trevor J., O’Brien, Catherine, De Carvalho, Daniel D.
Published in Cell (27.08.2015)
Published in Cell (27.08.2015)
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Coronavirus Disease 2019 and Parkinsonism: A Non‐post‐encephalitic Case
Faber, Ingrid, Brandão, Pedro R.P., Menegatti, Fiorella, Carvalho Bispo, Diógenes D., Maluf, Fernando B., Cardoso, Francisco
Published in Movement disorders (01.10.2020)
Published in Movement disorders (01.10.2020)
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Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes
Nassiri, Farshad, Chakravarthy, Ankur, Feng, Shengrui, Shen, Shu Yi, Nejad, Romina, Zuccato, Jeffrey A., Voisin, Mathew R., Patil, Vikas, Horbinski, Craig, Aldape, Kenneth, Zadeh, Gelareh, De Carvalho, Daniel D.
Published in Nature medicine (01.07.2020)
Published in Nature medicine (01.07.2020)
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Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans
Shinde, Rahul, Hezaveh, Kebria, Halaby, Marie Jo, Kloetgen, Andreas, Chakravarthy, Ankur, da Silva Medina, Tiago, Deol, Reema, Manion, Kieran P., Baglaenko, Yuriy, Eldh, Maria, Lamorte, Sara, Wallace, Drew, Chodisetti, Sathi Babu, Ravishankar, Buvana, Liu, Haiyun, Chaudhary, Kapil, Munn, David H., Tsirigos, Aristotelis, Madaio, Michael, Gabrielsson, Susanne, Touma, Zahi, Wither, Joan, De Carvalho, Daniel D., McGaha, Tracy L.
Published in Nature immunology (01.06.2018)
Published in Nature immunology (01.06.2018)
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DNA Methylation Screening Identifies Driver Epigenetic Events of Cancer Cell Survival
De Carvalho, Daniel D., Sharma, Shikhar, You, Jueng Soo, Su, Sheng-Fang, Taberlay, Phillippa C., Kelly, Theresa K., Yang, Xiaojing, Liang, Gangning, Jones, Peter A.
Published in Cancer cell (15.05.2012)
Published in Cancer cell (15.05.2012)
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Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells
Lima-Fernandes, Evelyne, Murison, Alex, da Silva Medina, Tiago, Wang, Yadong, Ma, Anqi, Leung, Cherry, Luciani, Genna M., Haynes, Jennifer, Pollett, Aaron, Zeller, Constanze, Duan, Shili, Kreso, Antonija, Barsyte-Lovejoy, Dalia, Wouters, Bradly G., Jin, Jian, Carvalho, Daniel D. De, Lupien, Mathieu, Arrowsmith, Cheryl H., O’Brien, Catherine A.
Published in Nature communications (29.03.2019)
Published in Nature communications (29.03.2019)
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Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA
Shen, Shu Yi, Burgener, Justin M., Bratman, Scott V., De Carvalho, Daniel D.
Published in Nature protocols (01.10.2019)
Published in Nature protocols (01.10.2019)
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Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes
Kent, Oliver A., Saha, Manipa, Coyaud, Etienne, Burston, Helen E., Law, Napoleon, Dadson, Keith, Chen, Sujun, Laurent, Estelle M., St-Germain, Jonathan, Sun, Ren X., Matsumoto, Yoshinori, Cowen, Justin, Montgomery-Song, Aaryn, Brown, Kevin R., Ishak, Charles, Rose, Jose La, De Carvalho, Daniel D., He, Housheng Hansen, Raught, Brian, Billia, Filio, Kannu, Peter, Rottapel, Robert
Published in Nature communications (16.09.2020)
Published in Nature communications (16.09.2020)
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Polycomb-Repressed Genes Have Permissive Enhancers that Initiate Reprogramming
Taberlay, Phillippa C., Kelly, Theresa K., Liu, Chun-Chi, You, Jueng Soo, De Carvalho, Daniel D., Miranda, Tina B., Zhou, Xianghong J., Liang, Gangning, Jones, Peter A.
Published in Cell (09.12.2011)
Published in Cell (09.12.2011)
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Epigenetic therapy in immune-oncology
Jones, Peter A., Ohtani, Hitoshi, Chakravarthy, Ankur, De Carvalho, Daniel D.
Published in Nature reviews. Cancer (01.03.2019)
Published in Nature reviews. Cancer (01.03.2019)
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Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet
Viner, Coby, Ishak, Charles A, Johnson, James, Walker, Nicolas J, Shi, Hui, Sjöberg-Herrera, Marcela K, Shen, Shu Yi, Lardo, Santana M, Adams, David J, Ferguson-Smith, Anne C, De Carvalho, Daniel D, Hainer, Sarah J, Bailey, Timothy L, Hoffman, Michael M
Published in Genome Biology (08.01.2024)
Published in Genome Biology (08.01.2024)
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Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
Mehdipour, Parinaz, Marhon, Sajid A., Ettayebi, Ilias, Chakravarthy, Ankur, Hosseini, Amir, Wang, Yadong, de Castro, Fabíola Attié, Loo Yau, Helen, Ishak, Charles, Abelson, Sagi, O’Brien, Catherine A., De Carvalho, Daniel D.
Published in Nature (London) (03.12.2020)
Published in Nature (London) (03.12.2020)
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Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer
Hosseini, Amir, Lindholm, Håvard T., Chen, Raymond, Mehdipour, Parinaz, Marhon, Sajid A., Ishak, Charles A., Moore, Paul C., Classon, Marie, Di Gioacchino, Andrea, Greenbaum, Benjamin, De Carvalho, Daniel D.
Published in Cell reports (Cambridge) (27.02.2024)
Published in Cell reports (Cambridge) (27.02.2024)
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Statins and oral biofilm: Simvastatin as a promising drug to control periodontal dysbiosis
Parolina de Carvalho, Rafaela D., Andrade Moreno, Jéssica, Roque, Sindy Magri, Chan, Daniel Cheuk Hong, Torrez, Willy Bustillos, Stipp, Rafael Nóbrega, Bueno‐Silva, Bruno, Lima, Patricia Oliveira, Cogo‐Müller, Karina
Published in Oral diseases (01.03.2024)
Published in Oral diseases (01.03.2024)
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