Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure
Cappelli, A, Mohr, GL, Gallelli, A, Rizzo, M, Anzini, M, Vomero, S, Mennuni, L, Ferrari, F, Makovec, F, Menziani, MC, De Benedetti, PG, Giorgi, G
Published in Journal of medicinal chemistry (06.05.2004)
Published in Journal of medicinal chemistry (06.05.2004)
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Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha(1d) adrenergic receptor
Leonardi, A, Barlocco, D, Montesano, F, Cignarella, G, Motta, G, Testa, R, Poggesi, E, Seeber, M, De Benedetti, PG, Fanelli, F
Published in Journal of medicinal chemistry (08.04.2004)
Published in Journal of medicinal chemistry (08.04.2004)
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Structural features of the inactive and active states of the melanin-concentrating hormone receptors: Insights from molecular simulations
Vitale, Rosa Maria, Pedone, Carlo, De Benedetti, Pier G., Fanelli, Francesca
Published in Proteins, structure, function, and bioinformatics (15.08.2004)
Published in Proteins, structure, function, and bioinformatics (15.08.2004)
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Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation
Scheer, A, Costa, T, Fanelli, F, De Benedetti, P G, Mhaouty-Kodja, S, Abuin, L, Nenniger-Tosato, M, Cotecchia, S
Published in Molecular pharmacology (01.02.2000)
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Published in Molecular pharmacology (01.02.2000)
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Activation Mechanism of Human Oxytocin Receptor: A Combined Study of Experimental and Computer-Simulated Mutagenesis
Fanelli, F, Barbier, P, Zanchetta, D, de Benedetti, P G, Chini, B
Published in Molecular pharmacology (01.07.1999)
Published in Molecular pharmacology (01.07.1999)
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Synthesis, Biological Evaluation, and Receptor Docking Simulations of 2-[(Acylamino)ethyl]-1,4-benzodiazepines as κ-Opioid Receptor Agonists Endowed with Antinociceptive and Antiamnesic Activity
Anzini, Maurizio, Canullo, Laura, Braile, Carlo, Cappelli, Andrea, Gallelli, Andrea, Vomero, Salvatore, Menziani, M. Cristina, De Benedetti, Pier G, Rizzo, Milena, Collina, Simona, Azzolina, Ornella, Sbacchi, Massimo, Ghelardini, Carla, Galeotti, Nicoletta
Published in Journal of medicinal chemistry (28.08.2003)
Published in Journal of medicinal chemistry (28.08.2003)
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Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure: Synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities
CAPPELLI, Andrea, ANZINI, Maurizio, GHELARDINI, Carla, COLLINA, Simona, VOMERO, Salvatore, MENNUNI, Laura, MAKOVEC, Francesco, DOUCET, Edith, HAMON, Michel, MENZIANI, M. Cristina, DE BENEDETTI, Pier G, GIORGI, Gianluca
Published in Bioorganic & medicinal chemistry (01.03.2002)
Published in Bioorganic & medicinal chemistry (01.03.2002)
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Novel Potent and Selective Central 5-HT3 Receptor Ligands Provided with Different Intrinsic Efficacy. 1. Mapping the Central 5-HT3 Receptor Binding Site by Arylpiperazine Derivatives
Cappelli, Andrea, Anzini, Maurizio, Vomero, Salvatore, Mennuni, Laura, Makovec, Francesco, Doucet, Edith, Hamon, Michel, Bruni, Giancarlo, Romeo, Maria R, Menziani, M. Cristina, De Benedetti, Pier G, Langer, Thierry
Published in Journal of medicinal chemistry (26.02.1998)
Published in Journal of medicinal chemistry (26.02.1998)
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Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha(1) adrenoceptor antagonists
Barlocco, D, Cignarella, G, Dal Piaz, Giovannoni, MP, De Benedetti, PG, Fanelli, F, Montesano, F, Poggesi, E, Leonardi, A
Published in Journal of medicinal chemistry (19.07.2001)
Published in Journal of medicinal chemistry (19.07.2001)
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Structural features of the inactive and active states of the melanin-concentrating hormone receiptors: Insights from molecular simulations
Vitale, Rosa Maria, Pedone, Carlo, De Benedetti, Pier G., Fanelli, Francesca
Published in Proteins, structure, function, and bioinformatics (01.09.2004)
Published in Proteins, structure, function, and bioinformatics (01.09.2004)
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Synthesis, pharmacological evaluation, and structure-activity relationship and quantitative structure-activity relationship studies on novel derivatives of 2,4-diamino-6,7-dimethoxyquinazoline alpha(1)-adrenoceptor antagonists
Leonardi, A, Motta, G, Boi, C, Testa, R, Poggesi, E, De Benedetti, PG, Menziani, MC
Published in Journal of medicinal chemistry (11.02.1999)
Published in Journal of medicinal chemistry (11.02.1999)
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Development of an IL-6 antagonist peptide that induces apoptosis in 7TD1 cells
Manfredini, Rossella, Tenedini, Elena, Siena, Michela, Tagliafico, Enrico, Montanari, Monica, Grande, Alexis, Zanocco-Marani, Tommaso, Poligani, Cristina, Zini, Roberta, Gemelli, Claudia, Bergamaschi, Anna, Vignudelli, Tatiana, De Rienzo, Francesca, De Benedetti, Pier Giuseppe, Menziani, Maria Cristina, Ferrari, Sergio
Published in Peptides (New York, N.Y. : 1980) (01.08.2003)
Published in Peptides (New York, N.Y. : 1980) (01.08.2003)
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Seeking for binding determinants of the prion protein to human plasminogen
MENZIANI, M. C., DE BENEDETTI, P. G., LANGELLA, E., BARONE, V.
Published in Molecular physics (10.09.2003)
Published in Molecular physics (10.09.2003)
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Novel Potent and Selective Central 5-HT3 Receptor Ligands Provided with Different Intrinsic Efficacy. 2. Molecular Basis of the Intrinsic Efficacy of Arylpiperazine Derivatives at the Central 5-HT3 Receptors
Cappelli, Andrea, Anzini, Maurizio, Vomero, Salvatore, Canullo, Laura, Mennuni, Laura, Makovec, Francesco, Doucet, Edith, Hamon, Michel, Menziani, M. Cristina, De Benedetti, Pier G, Bruni, Giancarlo, Romeo, Maria R, Giorgi, Gianluca, Donati, Alessandro
Published in Journal of medicinal chemistry (06.05.1999)
Published in Journal of medicinal chemistry (06.05.1999)
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