A random six-phase switch regulates pneumococcal virulence via global epigenetic changes
Manso, Ana Sousa, Chai, Melissa H., Atack, John M., Furi, Leonardo, De Ste Croix, Megan, Haigh, Richard, Trappetti, Claudia, Ogunniyi, Abiodun D., Shewell, Lucy K., Boitano, Matthew, Clark, Tyson A., Korlach, Jonas, Blades, Matthew, Mirkes, Evgeny, Gorban, Alexander N., Paton, James C., Jennings, Michael P., Oggioni, Marco R.
Published in Nature communications (30.09.2014)
Published in Nature communications (30.09.2014)
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Journal Article
Prevalence of phase variable epigenetic invertons among host-associated bacteria
Huang, Xueting, Wang, Juanjuan, Li, Jing, Liu, Yanni, Liu, Xue, Li, Zeyao, Kurniyati, Kurni, Deng, Yijie, Wang, Guilin, Ralph, Joseph D, De Ste Croix, Megan, Escobar-Gonzalez, Sara, Roberts, Richard J, Veening, Jan-Willem, Lan, Xun, Oggioni, Marco R, Li, Chunhao, Zhang, Jing-Ren
Published in Nucleic acids research (18.11.2020)
Published in Nucleic acids research (18.11.2020)
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Journal Article
Lineage‐specific evolution and gene flow in Listeria monocytogenes are independent of bacteriophages
Zamudio, Roxana, Haigh, Richard D., Ralph, Joseph D., De Ste Croix, Megan, Tasara, Taurai, Zurfluh, Katrin, Kwun, Min Jung, Millard, Andrew D., Bentley, Stephen D., Croucher, Nicholas J., Stephan, Roger, Oggioni, Marco R.
Published in Environmental microbiology (01.12.2020)
Published in Environmental microbiology (01.12.2020)
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Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens
Mitsi, Elena, Carniel, Beatriz, Reiné, Jesús, Rylance, Jamie, Zaidi, Seher, Soares-Schanoski, Alessandra, Connor, Victoria, Collins, Andrea M, Schlitzer, Andreas, Nikolaou, Elissavet, Solórzano, Carla, Pojar, Sherin, Hill, Helen, Hyder-Wright, Angela D, Jambo, Kondwani C, Oggioni, Marco R, De Ste Croix, Megan, Gordon, Stephen B, Jochems, Simon P, Ferreira, Daniela M
Published in American journal of respiratory and critical care medicine (01.02.2020)
Published in American journal of respiratory and critical care medicine (01.02.2020)
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Deletion of the Zinc Transporter Lipoprotein AdcAII Causes Hyperencapsulation of Streptococcus pneumoniae Associated with Distinct Alleles of the Type I Restriction-Modification System
Durmort, Claire, Ercoli, Giuseppe, Ramos-Sevillano, Elisa, Chimalapati, Suneeta, Haigh, Richard D, De Ste Croix, Megan, Gould, Katherine, Hinds, Jason, Guerardel, Yann, Vernet, Thierry, Oggioni, Marco, Brown, Jeremy S
Published in mBio (31.03.2020)
Published in mBio (31.03.2020)
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Journal Article
Phase-variable methylation and epigenetic regulation by type I restriction–modification systems
De Ste Croix, Megan, Vacca, Irene, Kwun, Min Jung, Ralph, Joseph D., Bentley, Stephen D., Haigh, Richard, Croucher, Nicholas J, Oggioni, Marco R
Published in FEMS microbiology reviews (01.08.2017)
Published in FEMS microbiology reviews (01.08.2017)
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Journal Article
Long-term evolution of Streptococcus mitis and Streptococcus pneumoniae leads to higher genetic diversity within rather than between human populations
Davison, Charlotte, Tallman, Sam, de Ste-Croix, Megan, Antonio, Martin, Oggioni, Marco R, Kwambana-Adams, Brenda, Freund, Fabian, Beleza, Sandra
Published in PLoS genetics (06.06.2024)
Published in PLoS genetics (06.06.2024)
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Journal Article
Excision-reintegration at a pneumococcal phase-variable restriction-modification locus drives within- and between-strain epigenetic differentiation and inhibits gene acquisition
Kwun, Min Jung, Oggioni, Marco R, De Ste Croix, Megan, Bentley, Stephen D, Croucher, Nicholas J
Published in Nucleic acids research (30.11.2018)
Published in Nucleic acids research (30.11.2018)
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Journal Article
Methylation Warfare: Interaction of Pneumococcal Bacteriophages with Their Host
Furi, Leonardo, Crawford, Liam A, Rangel-Pineros, Guillermo, Manso, Ana S, De Ste Croix, Megan, Haigh, Richard D, Kwun, Min J, Engelsen Fjelland, Kristine, Gilfillan, Gregor D, Bentley, Stephen D, Croucher, Nicholas J, Clokie, Martha R, Oggioni, Marco R
Published in Journal of bacteriology (01.10.2019)
Published in Journal of bacteriology (01.10.2019)
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Journal Article
Lipopeptidomimetics derived from teixobactin have potent antibacterial activity against Staphylococcus aureus
Girt, Georgina C., Mahindra, Amit, Al Jabri, Zaaima J. H., De Ste Croix, Megan, Oggioni, Marco R., Jamieson, Andrew G.
Published in Chemical communications (Cambridge, England) (13.03.2018)
Published in Chemical communications (Cambridge, England) (13.03.2018)
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Development of a robust and quantitative high-throughput screening method for assessing phenotypic variation in large Neisseria meningitidis isolate collections
Farzand, Robeena, Croix, Megan De Ste, Dave, Neelam, Bayliss, Christopher D.
Published in MethodsX (01.01.2023)
Published in MethodsX (01.01.2023)
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Journal Article
Intracellular survival of Streptococcus pneumoniae in human alveolar macrophages is augmented with HIV infection
Nyazika, Tinashe K, Sibale, Lusako, Phiri, Joseph, De Ste Croix, Megan, Jasiunaite, Zydrune, Mkandawire, Christopher, Malamba, Rose, Kankwatira, Anstead, Manduwa, Miriam, Ferreira, Daniela M, Nyirenda, Tonney S, Oggioni, Marco R, Mwandumba, Henry C, Jambo, Kondwani C
Published in Frontiers in immunology (20.09.2022)
Published in Frontiers in immunology (20.09.2022)
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Journal Article
A small RNA encoded in the Rv2660c locus of Mycobacterium tuberculosis is induced during starvation and infection
Houghton, Joanna, Cortes, Teresa, Schubert, Olga, Rose, Graham, Rodgers, Angela, De Ste Croix, Megan, Aebersold, Rudolf, Young, Douglas B, Arnvig, Kristine B
Published in PloS one (12.12.2013)
Published in PloS one (12.12.2013)
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Journal Article
Pathogenic Differences of Type 1 Restriction-Modification Allele Variants in Experimental Listeria monocytogenes Meningitis
Zbinden, Florian R, De Ste Croix, Megan, Grandgirard, Denis, Haigh, Richard D, Vacca, Irene, Zamudio, Roxana, Goodall, Emily C A, Stephan, Roger, Oggioni, Marco R, Leib, Stephen L
Published in Frontiers in cellular and infection microbiology (30.10.2020)
Published in Frontiers in cellular and infection microbiology (30.10.2020)
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High-throughput phenotype-to-genotype testing of meningococcal carriage and disease isolates detects genetic determinants of disease-relevant phenotypic traits
Farzand, Robeena, Kimani, Mercy W, Mourkas, Evangelos, Jama, Abdullahi, Clark, Jack L, De Ste Croix, Megan, Monteith, William M, Lucidarme, Jay, Oldfield, Neil J, Turner, David P J, Borrow, Ray, Martinez-Pomares, Luisa, Sheppard, Samuel K, Bayliss, Christopher D
Published in mBio (30.10.2024)
Published in mBio (30.10.2024)
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Journal Article
Lipopeptidomimetics derived from teixobactin have potent antibacterial activity against Staphylococcus aureusElectronic supplementary information (ESI) available: Synthetic methods, LCMS, HPLC, HRMS, 1D NMR, TOCSY NMR. See DOI: 10.1039/c7cc06093a
Girt, Georgina C, Mahindra, Amit, Al Jabri, Zaaima J. H, De Ste Croix, Megan, Oggioni, Marco R, Jamieson, Andrew G
Year of Publication 13.03.2018
Year of Publication 13.03.2018
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Journal Article
Dissecting meningococcal disease and carriage traits using high throughput phenotypic testing
Farzand, Robeena, Mourkas, Evangelos, Ste Croix, Megan De, Dave, Neelam, Jama, Abdullahi, Oldfield, Neil, Lucidarme, Jay, Turner, David, Borrow, Ray, Martinez-Pomares, Luisa, Sheppard, Samuel, Bayliss, Christopher
Published in Access microbiology (18.05.2022)
Published in Access microbiology (18.05.2022)
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Journal Article
Dissecting meningococcal disease and carriage traits using high throughput phenotypic testing
De Ste Croix, Megan, Neelam, Dave, Oldfield, Neil, Lucidarme, Jay, Turner, David, Borrow, Ray, Sheppard, Samuel, Martinez-Pomares, Luisa, Bayliss, Christopher
Published in Access microbiology (01.07.2020)
Published in Access microbiology (01.07.2020)
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