Synthesis of 4'-Substituted Carbocyclic Uracil Derivatives and Their Monophosphate Prodrugs as Potential Antiviral Agents
Biteau, Nicolas G, Amichai, Sarah A, Azadi, Niloufar, De, Ramyani, Downs-Bowen, Jessica, Lecher, Julia C, MacBrayer, Tamara, Schinazi, Raymond F, Amblard, Franck
Published in Viruses (01.02.2023)
Published in Viruses (01.02.2023)
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Journal Article
Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections
Hurwitz, Selwyn J, De, Ramyani, LeCher, Julia C, Downs-Bowen, Jessica A, Goh, Shu Ling, Zandi, Keivan, McBrayer, Tamara, Amblard, Franck, Patel, Dharmeshkumar, Kohler, James J, Bhasin, Manoj, Dobosh, Brian S, Sukhatme, Vikas, Tirouvanziam, Rabindra M, Schinazi, Raymond F
Published in Viruses (01.04.2024)
Published in Viruses (01.04.2024)
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Journal Article
Synthesis of Novel N4-Hydrocytidine Analogs as Potential Anti-SARS-CoV-2 Agents
Amblard, Franck, LeCher, Julia C., De, Ramyani, Goh, Shu Ling, Li, Chengwei, Kasthuri, Mahesh, Biteau, Nicolas, Zhou, Longhu, Tber, Zahira, Downs-Bowen, Jessica, Zandi, Keivan, Schinazi, Raymond F.
Published in Pharmaceuticals (Basel, Switzerland) (14.09.2022)
Published in Pharmaceuticals (Basel, Switzerland) (14.09.2022)
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Journal Article
Discovery of a 2'-Fluoro,2'-Bromouridine Phosphoramidate Prodrug Exhibiting Anti-Yellow Fever Virus Activity in Culture and in Mice
LeCher, Julia C, Zandi, Keivan, Costa, Vivian Vasconcelos, Amblard, Franck, Tao, Sijia, Patel, Dharmeshkumar, Lee, Sujin, da Silva Santos, Felipe Rocha, Goncalves, Matheus Rodrigues, Queroz-Junior, Celso Martins, Marim, Fernanda Martins, Musall, Katie, Goh, Shu Ling, McBrayer, Tamara, Downs-Bowen, Jessica, De, Ramyani, Azadi, Niloufar, Kohler, James, Teixeira, Mauro Martins, Schinazi, Raymond F
Published in Microorganisms (Basel) (22.10.2022)
Published in Microorganisms (Basel) (22.10.2022)
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Journal Article
Informatics and Computational Approaches for the Discovery and Optimization of Natural Product-Inspired Inhibitors of the SARS-CoV‑2 2′‑O‑Methyltransferase
Hanna, George S., Benjamin, Menny M., Choo, Yeun-Mun, De, Ramyani, Schinazi, Raymond F., Nielson, Sarah E., Hevel, Joan M., Hamann, Mark T.
Published in Journal of natural products (Washington, D.C.) (23.02.2024)
Published in Journal of natural products (Washington, D.C.) (23.02.2024)
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Journal Article
Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease
Amblard, Franck, LeCher, Julia C., De, Ramyani, Zhou, Shaoman, Liu, Peng, Goh, Shu Ling, Tao, Sijia, Patel, Dharmeshkumar, Downs-Bowen, Jessica, Zandi, Keivan, Zhang, Huanchun, Chaudhry, Gitika, McBrayer, Tamara, Muczynski, Michael, Al-Homoudi, Abdullah, Engel, Joseph, Lan, Shuiyun, Sarafianos, Stefan G., Kovari, Ladislau C., Schinazi, Raymond F.
Published in European journal of medicinal chemistry (15.03.2024)
Published in European journal of medicinal chemistry (15.03.2024)
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Journal Article
Cannabinoid-Inspired Inhibitors of the SARS-CoV-2 Coronavirus 2′-O-Methyltransferase (2′-O-MTase) Non-Structural Protein (Nsp10–16)
Benjamin, Menny M., Hanna, George S., Dickinson, Cody F., Choo, Yeun-Mun, Wang, Xiaojuan, Downs-Bowen, Jessica A., De, Ramyani, McBrayer, Tamara R., Schinazi, Raymond F., Nielson, Sarah E., Hevel, Joan M., Pandey, Pankaj, Doerksen, Robert J., Townsend, Danyelle M., Zhang, Jie, Ye, Zhiwei, Wyer, Scott, Bialousow, Lucas, Hamann, Mark T.
Published in Molecules (Basel, Switzerland) (28.10.2024)
Published in Molecules (Basel, Switzerland) (28.10.2024)
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Journal Article
Synthesis of Novel IN/I[sup.4]-Hydrocytidine Analogs as Potential Anti-SARS-CoV-2 Agents
Amblard, Franck, LeCher, Julia C, De, Ramyani, Goh, Shu Ling, Li, Chengwei, Kasthuri, Mahesh, Biteau, Nicolas, Zhou, Longhu, Tber, Zahira, Downs-Bowen, Jessica, Zandi, Keivan, Schinazi, Raymond F
Published in Pharmaceuticals (Basel, Switzerland) (01.09.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.09.2022)
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Journal Article
Rhinoviruses A and C elicit long‐lasting antibody responses with limited cross‐neutralization
Bochkov, Yury A., Devries, Mark, Tetreault, Kaitlin, Gangnon, Ronald, Lee, Sujin, Bacharier, Leonard B., Busse, William W., Camargo, Carlos A., Choi, Timothy, Cohen, Robyn, De, Ramyani, DeMuri, Gregory P., Fitzpatrick, Anne M., Gergen, Peter J., Grindle, Kristine, Gruchalla, Rebecca, Hartert, Tina, Hasegawa, Kohei, Khurana Hershey, Gurjit K., Holt, Patrick, Homil, Kiara, Jartti, Tuomas, Kattan, Meyer, Kercsmar, Carolyn, Kim, Haejin, Laing, Ingrid A., Le Souëf, Peter N., Liu, Andrew H., Mauger, David T., Pappas, Tressa, Patel, Shilpa J., Phipatanakul, Wanda, Pongracic, Jacqueline, Seroogy, Christine, Sly, Peter D., Tisler, Christopher, Wald, Ellen R., Wood, Robert, Lemanske, Robert F., Jackson, Daniel J., Gern, James E.
Published in Journal of medical virology (01.08.2023)
Published in Journal of medical virology (01.08.2023)
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Journal Article
Development of robust antiviral assays using relevant apical-out human airway organoids
Lee, Ji-Hoon, LeCher, Julia C, Parigoris, Eric, Shinagawa, Noriyuki, Sentosa, Jason, Manfredi, Candela, Goh, Shu Ling, De, Ramyani, Tao, Sijia, Zandi, Keivan, Amblard, Franck, Sorscher, Eric J, Spence, Jason R, Tirouvanziam, Rabindra, Schinazi, Raymond F, Takayama, Shuichi
Published in bioRxiv (12.07.2024)
Published in bioRxiv (12.07.2024)
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Journal Article
Stably-Inverted Apical-Out Human Upper Airway Organoids for SARS-CoV-2 Infection and Therapeutic Testing
Ji-Hoon, Lee, Lecher, Julia C, Parigoris, Eric, Shinagawa, Noriyuki, Sentosa, Jason, Candela Manfredi, Goh, Shu Ling, De, Ramyani, Tao, Sijia, Zandi, Keivan, Amblard, Franck, Sorscher, Eric J, Spence, Jason R, Tirouvanziam, Rabindra, Schinazi, Raymond F, Takayama, Shuichi
Published in bioRxiv (04.01.2024)
Published in bioRxiv (04.01.2024)
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