Direct modifications of the cyclic peptide Polymyxin B leading to analogues with enhanced in vitro antibacterial activity
Brown, Pamela, Abdulle, Omar, Boakes, Steven, Duperchy, Esther, Moss, Stephen, Simonovic, Mona, Stanway, Steven, Wilson, Antoinette, Dawson, Michael J.
Published in Bioorganic & medicinal chemistry letters (01.06.2020)
Published in Bioorganic & medicinal chemistry letters (01.06.2020)
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Design of Next Generation Polymyxins with Lower Toxicity: The Discovery of SPR206
Brown, Pamela, Abbott, Elizabeth, Abdulle, Omar, Boakes, Steven, Coleman, Scott, Divall, Naomi, Duperchy, Esther, Moss, Stephen, Rivers, Dean, Simonovic, Mona, Singh, Jaspal, Stanway, Steven, Wilson, Antoinette, Dawson, Michael J
Published in ACS infectious diseases (11.10.2019)
Published in ACS infectious diseases (11.10.2019)
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Influence of Lipophilicity on the Antibacterial Activity of Polymyxin Derivatives and on Their Ability to Act as Potentiators of Rifampicin
Brown, Pamela, Abdulle, Omar, Boakes, Steven, Divall, Naomi, Duperchy, Esther, Ganeshwaran, Sonia, Lester, Roy, Moss, Stephen, Rivers, Dean, Simonovic, Mona, Singh, Jaspal, Stanway, Steven, Wilson, Antoinette, Dawson, Michael J
Published in ACS infectious diseases (09.04.2021)
Published in ACS infectious diseases (09.04.2021)
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Directed Evolution of an Amine Oxidase Possessing both Broad Substrate Specificity and High Enantioselectivity
Carr, Reuben, Alexeeva, Marina, Enright, Alexis, Eve, Tom S. C., Dawson, Michael J., Turner, Nicholas J.
Published in Angewandte Chemie International Edition (13.10.2003)
Published in Angewandte Chemie International Edition (13.10.2003)
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Directed Evolution of an Amine Oxidase for the Preparative Deracemisation of Cyclic Secondary Amines
Carr, Reuben, Alexeeva, Marina, Dawson, Michael J, Gotor-Fernández, Vicente, Humphrey, Cara E, Turner, Nicholas J
Published in Chembiochem : a European journal of chemical biology (01.04.2005)
Published in Chembiochem : a European journal of chemical biology (01.04.2005)
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The Production of Novel Sordarin Analogues by Biotransformation
HALL, RICHARD M., DAWSON, MICHAEL J., JONES, CAROL A., ROBERTS, ANDREW D., SIDEBOTTOM, PHILIP J., STEAD, PAUL, TAYLOR, NICK L.
Published in Journal of antibiotics (01.11.2001)
Published in Journal of antibiotics (01.11.2001)
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Dissecting Structural and Functional Diversity of the Lantibiotic Mersacidin
Appleyard, Antony N., Choi, Shaila, Read, Daniel M., Lightfoot, Ann, Boakes, Steven, Hoffmann, Anja, Chopra, Ian, Bierbaum, Gabriele, Rudd, Brian A.M., Dawson, Michael J., Cortes, Jesus
Published in Chemistry & biology (29.05.2009)
Published in Chemistry & biology (29.05.2009)
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Revised pathway for the biosynthesis of aristeromycin and neplanocin A from D-glucose in Streptomyces citricolor
Hill, Jason M, Jenkins, Gareth N, Rush, Cliff P, Turner, Nicholas J, Willetts, Andrew J, Buss, Antony D, Dawson, Michael J, Rudd, Brian A. M
Published in Journal of the American Chemical Society (01.05.1995)
Published in Journal of the American Chemical Society (01.05.1995)
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