Diverse somatic mutation patterns and pathway alterations in human cancers
Li, Li, Waring, Paul, Stern, Howard M, Stokoe, David, Zheng, Jianbiao, Eberhard, David A, Chaudhuri, Subhra, Moorhead, Martin, Wang, Weiru, Yue, Peng, Modrusan, Zora, Pujara, Kanan, Faham, Malek, Davis, David P, Eigenbrot, Charles, Tomsho, Lynn P, Janakiraman, Vasantharajan, Stinson, Jeremy, Bourgon, Richard, Carlton, Victoria E. H, Jaiswal, Bijay S, Seshagiri, Somasekar, Kaminker, Joshua S, Schuster, Stephan C, Kan, Zhengyan, Peters, Brock A, Cordes, Shaun, Zhang, Zemin, de Sauvage, Frederic J, Bhatt, Deepali, Haverty, Peter M, Yuan, Wenlin
Published in Nature (London) (12.08.2010)
Published in Nature (London) (12.08.2010)
Get full text
Journal Article
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
Degtyarev, Michael, De Mazière, Ann, Orr, Christine, Lin, Jie, Lee, Brian B, Tien, Janet Y, Prior, Wei W, van Dijk, Suzanne, Wu, Hong, Gray, Daniel C, Davis, David P, Stern, Howard M, Murray, Lesley J, Hoeflich, Klaus P, Klumperman, Judith, Friedman, Lori S, Lin, Kui
Published in The Journal of cell biology (06.10.2008)
Published in The Journal of cell biology (06.10.2008)
Get full text
Journal Article
The STARD9/Kif16a Kinesin Associates with Mitotic Microtubules and Regulates Spindle Pole Assembly
Torres, Jorge Z., Summers, Matthew K., Peterson, David, Brauer, Matthew J., Lee, James, Senese, Silvia, Gholkar, Ankur A., Lo, Yu-Chen, Lei, Xingye, Jung, Kenneth, Anderson, David C., Davis, David P., Belmont, Lisa, Jackson, Peter K.
Published in Cell (09.12.2011)
Published in Cell (09.12.2011)
Get full text
Journal Article
Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors
Jaiswal, Bijay S, Janakiraman, Vasantharajan, Kljavin, Noelyn M, Eastham-Anderson, Jeffrey, Cupp, James E, Liang, Yuxin, Davis, David P, Hoeflich, Klaus P, Seshagiri, Somasekar
Published in PloS one (27.05.2009)
Published in PloS one (27.05.2009)
Get full text
Journal Article
whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis
Dompe, Nicholas, Rivers, Celina Sanchez, Li, Li, Cordes, Shaun, Schwickart, Martin, Punnoose, Elizabeth A, Amler, Lukas, Seshagiri, Somasekar, Tang, Jerry, Modrusan, Zora, Davis, David P
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
Get full text
Journal Article
Oncogenic BRAF is required for tumor growth and maintenance in melanoma models
HOEFLICH, Klaus P, GRAY, Daniel C, MURRAY, Lesley J, DAVIS, David P, SESHAGIRI, Somasekar, EBY, Michael T, TIEN, Janet Y, LEO WONG, BOWER, Janeko, GOGINENI, Alvin, JIPING ZHA, COLE, Mary J, STERN, Howard M
Published in Cancer research (Chicago, Ill.) (15.01.2006)
Published in Cancer research (Chicago, Ill.) (15.01.2006)
Get full text
Journal Article
Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers
GRAY, Daniel, JUBB, Adrian M, DE SAUVAGE, Frederic J, DAVIS, David P, HOGUE, Deborah, DOWD, Patrick, KLJAVIN, Noelyn, YI, Sothy, WEI BAI, FRANTZ, Gretchen, ZEMIN ZHANG, KOEPPEN, Hartmut
Published in Cancer research (Chicago, Ill.) (01.11.2005)
Published in Cancer research (Chicago, Ill.) (01.11.2005)
Get full text
Journal Article
Kinome siRNA screen identifies regulators of ciliogenesis and hedgehog signal transduction
Evangelista, Marie, Lim, Tze Yang, Lee, James, Parker, Leon, Ashique, Amir, Peterson, Andrew S, Ye, Weilan, Davis, David P, de Sauvage, Frederic J
Published in Science signaling (30.09.2008)
Published in Science signaling (30.09.2008)
Get more information
Journal Article
PPM1H is a p27 phosphatase implicated in trastuzumab resistance
Lee-Hoeflich, Si Tuen, Pham, Thinh Q, Dowbenko, Don, Munroe, Xander, Lee, James, Li, Li, Zhou, Wei, Haverty, Peter M, Pujara, Kanan, Stinson, Jeremy, Chan, Sara M, Eastham-Anderson, Jeffrey, Pandita, Ajay, Seshagiri, Somasekar, Hoeflich, Klaus P, Turashvili, Gulisa, Gelmon, Karen A, Aparicio, Samuel A, Davis, David P, Sliwkowski, Mark X, Stern, Howard M
Published in Cancer discovery (01.09.2011)
Published in Cancer discovery (01.09.2011)
Get full text
Journal Article
Discovering cancer genes by integrating network and functional properties
Li, Li, Zhang, Kangyu, Lee, James, Cordes, Shaun, Davis, David P, Tang, Zhijun
Published in BMC medical genomics (19.09.2009)
Published in BMC medical genomics (19.09.2009)
Get full text
Journal Article
pHUSH: a single vector system for conditional gene expression
Gray, Daniel C, Hoeflich, Klaus P, Peng, Li, Gu, Zhenyu, Gogineni, Alvin, Murray, Lesley J, Eby, Mike, Kljavin, Noelyn, Seshagiri, Somasekar, Cole, Mary J, Davis, David P
Published in BMC biotechnology (26.09.2007)
Published in BMC biotechnology (26.09.2007)
Get full text
Journal Article
A Chemosensitization Screen Identifies TP53RK, a Kinase that Restrains Apoptosis after Mitotic Stress
PETERSON, David, LEE, James, LEI, Xingye C, FORREST, William F, DAVIS, David P, JACKSON, Peter K, BELMONT, Lisa D
Published in Cancer research (Chicago, Ill.) (01.08.2010)
Published in Cancer research (Chicago, Ill.) (01.08.2010)
Get full text
Journal Article
The Six N-linked Carbohydrates of the Lutropin/Choriogonadotropin Receptor Are Not Absolutely Required for Correct Folding, Cell Surface Expression, Hormone Binding, or Signal Transduction
Davis, David P, Rozell, Tim G, Liu, Xuebo, Segaloff, Deborah L
Published in Molecular endocrinology (Baltimore, Md.) (01.05.1997)
Published in Molecular endocrinology (Baltimore, Md.) (01.05.1997)
Get full text
Journal Article
Regulation of ERK3/MAPK6 expression by BRAF
HOEFLICH, Klaus P, EBY, Michael T, FORREST, William F, GRAY, Daniel C, TIEN, Janet Y, STERN, Howard M, MURRAY, Lesley J, DAVIS, David P, MODRUSAN, Zora, SESHAGIRI, Somasekar
Published in International journal of oncology (01.10.2006)
Published in International journal of oncology (01.10.2006)
Get full text
Journal Article
Inducible BRAF suppression models for melanoma tumorigenesis
Hoeflich, Klaus P, Jaiswal, Bijay, Davis, David P, Seshagiri, Somasekar
Published in Methods in enzymology (2008)
Published in Methods in enzymology (2008)
Get more information
Journal Article
Inhibition of Amyloid Fiber Assembly by Both BiP and Its Target Peptide
Davis, David P, Raffen, Rosemarie, Dul, Jeanne L, Vogen, Shawn M, Williamson, Edward K, Stevens, Fred J, Argon, Yair
Published in Immunity (Cambridge, Mass.) (01.10.2000)
Published in Immunity (Cambridge, Mass.) (01.10.2000)
Get full text
Journal Article
Both the environment and somatic mutations govern the aggregation pathway of pathogenic immunoglobulin light chain 1 1Edited by A. Fersht
Davis, David P., Gallo, Gloria, Vogen, Shawn M., Dul, Jeanne L., Sciarretta, Kimberly L., Kumar, Asok, Raffen, Rosemarie, Stevens, Fred J., Argon, Yair
Published in Journal of molecular biology (01.11.2001)
Published in Journal of molecular biology (01.11.2001)
Get full text
Journal Article