Analysis of sub-kilobase chromatin topology reveals nano-scale regulatory interactions with variable dependence on cohesin and CTCF
Aljahani, Abrar, Hua, Peng, Karpinska, Magdalena A, Quililan, Kimberly, Davies, James O J, Oudelaar, A Marieke
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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BET inhibition disrupts transcription but retains enhancer-promoter contact
Crump, Nicholas T, Ballabio, Erica, Godfrey, Laura, Thorne, Ross, Repapi, Emmanouela, Kerry, Jon, Tapia, Marta, Hua, Peng, Lagerholm, Christoffer, Filippakopoulos, Panagis, Davies, James O J, Milne, Thomas A
Published in Nature communications (11.01.2021)
Published in Nature communications (11.01.2021)
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Direct correction of haemoglobin E β-thalassaemia using base editors
Badat, Mohsin, Ejaz, Ayesha, Hua, Peng, Rice, Siobhan, Zhang, Weijiao, Hentges, Lance D, Fisher, Christopher A, Denny, Nicholas, Schwessinger, Ron, Yasara, Nirmani, Roy, Noemi B A, Issa, Fadi, Roy, Andi, Telfer, Paul, Hughes, Jim, Mettananda, Sachith, Higgs, Douglas R, Davies, James O J
Published in Nature communications (19.04.2023)
Published in Nature communications (19.04.2023)
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High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
Downes, Damien J, Beagrie, Robert A, Gosden, Matthew E, Telenius, Jelena, Carpenter, Stephanie J, Nussbaum, Lea, De Ornellas, Sara, Sergeant, Martin, Eijsbouts, Chris Q, Schwessinger, Ron, Kerry, Jon, Roberts, Nigel, Shivalingam, Arun, El-Sagheer, Afaf, Oudelaar, A Marieke, Brown, Tom, Buckle, Veronica J, Davies, James O J, Hughes, Jim R
Published in Nature communications (22.01.2021)
Published in Nature communications (22.01.2021)
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MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia
Crump, Nicholas T, Smith, Alastair L, Godfrey, Laura, Dopico-Fernandez, Ana M, Denny, Nicholas, Harman, Joe R, Hamley, Joseph C, Jackson, Nicole E, Chahrour, Catherine, Riva, Simone, Rice, Siobhan, Kim, Jaehoon, Basrur, Venkatesha, Fermin, Damian, Elenitoba-Johnson, Kojo, Roeder, Robert G, Allis, C David, Roberts, Irene, Roy, Anindita, Geng, Huimin, Davies, James O J, Milne, Thomas A
Published in Nature communications (25.08.2023)
Published in Nature communications (25.08.2023)
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Determining chromatin architecture with Micro Capture-C
Hamley, Joseph C, Li, Hangpeng, Denny, Nicholas, Downes, Damien, Davies, James O J
Published in Nature protocols (01.06.2023)
Published in Nature protocols (01.06.2023)
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Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains
Oudelaar, A Marieke, Davies, James O J, Hanssen, Lars L P, Telenius, Jelena M, Schwessinger, Ron, Liu, Yu, Brown, Jill M, Downes, Damien J, Chiariello, Andrea M, Bianco, Simona, Nicodemi, Mario, Buckle, Veronica J, Dekker, Job, Higgs, Douglas R, Hughes, Jim R
Published in Nature genetics (01.12.2018)
Published in Nature genetics (01.12.2018)
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Multiplexed analysis of chromosome conformation at vastly improved sensitivity
Davies, James O J, Telenius, Jelena M, McGowan, Simon J, Roberts, Nigel A, Taylor, Stephen, Higgs, Douglas R, Hughes, Jim R
Published in Nature methods (01.01.2016)
Published in Nature methods (01.01.2016)
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Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus
Downes, Damien J, Cross, Amy R, Hua, Peng, Roberts, Nigel, Schwessinger, Ron, Cutler, Antony J, Munis, Altar M, Brown, Jill, Mielczarek, Olga, de Andrea, Carlos E, Melero, Ignacio, Gill, Deborah R, Hyde, Stephen C, Knight, Julian C, Todd, John A, Sansom, Stephen N, Issa, Fadi, Davies, James O J, Hughes, Jim R
Published in Nature genetics (01.11.2021)
Published in Nature genetics (01.11.2021)
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Journal Article
Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture
Downes, Damien J, Smith, Alastair L, Karpinska, Magdalena A, Velychko, Taras, Rue-Albrecht, Kevin, Sims, David, Milne, Thomas A, Davies, James O J, Oudelaar, A Marieke, Hughes, Jim R
Published in Nature protocols (01.02.2022)
Published in Nature protocols (01.02.2022)
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Journal Article
Author Correction: Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture
Downes, Damien J, Smith, Alastair L, Karpinska, Magdalena A, Velychko, Taras, Rue-Albrecht, Kevin, Sims, David, Milne, Thomas A, Davies, James O J, Oudelaar, A Marieke, Hughes, Jim R
Published in Nature protocols (01.10.2023)
Published in Nature protocols (01.10.2023)
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Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity
Ooi, Wen Fong, Xing, Manjie, Xu, Chang, Yao, Xiaosai, Ramlee, Muhammad Khairul, Lim, Mei Chee, Cao, Fan, Lim, Kevin, Babu, Deepak, Poon, Lai-Fong, Lin Suling, Joyce, Qamra, Aditi, Irwanto, Astrid, Qu Zhengzhong, James, Nandi, Tannistha, Lee-Lim, Ai Ping, Chan, Yang Sun, Tay, Su Ting, Lee, Ming Hui, Davies, James O J, Wong, Wai Keong, Soo, Khee Chee, Chan, Weng Hoong, Ong, Hock Soo, Chow, Pierce, Wong, Chow Yin, Rha, Sun Young, Liu, Jianjun, Hillmer, Axel M, Hughes, Jim R, Rozen, Steve, Teh, Bin Tean, Fullwood, Melissa Jane, Li, Shang, Tan, Patrick
Published in Nature communications (28.09.2016)
Published in Nature communications (28.09.2016)
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HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
Yan, TingDong, Ooi, Wen Fong, Qamra, Aditi, Cheung, Alice, Ma, DongLiang, Sundaram, Gopinath Meenakshi, Xu, Chang, Xing, Manjie, Poon, LaiFong, Wang, Jing, Loh, Yan Ping, Ho, Jess Hui Jie, Ng, Joscelyn Jun Quan, Ramlee, Muhammad Khairul, Aswad, Luay, Rozen, Steve G, Ghosh, Sujoy, Bard, Frederic A, Sampath, Prabha, Tergaonkar, Vinay, Davies, James O J, Hughes, Jim R, Goh, Eyleen, Bi, Xuezhi, Fullwood, Melissa Jane, Tan, Patrick, Li, Shang
Published in Nature communications (08.01.2018)
Published in Nature communications (08.01.2018)
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Defining genome architecture at base-pair resolution
Hua, Peng, Badat, Mohsin, Hanssen, Lars L P, Hentges, Lance D, Crump, Nicholas, Downes, Damien J, Jeziorska, Danuta M, Oudelaar, A Marieke, Schwessinger, Ron, Taylor, Stephen, Milne, Thomas A, Hughes, Jim R, Higgs, Doug R, Davies, James O J
Published in Nature (London) (01.07.2021)
Published in Nature (London) (01.07.2021)
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How best to identify chromosomal interactions: a comparison of approaches
Davies, James O J, Oudelaar, A Marieke, Higgs, Douglas R, Hughes, Jim R
Published in Nature methods (01.02.2017)
Published in Nature methods (01.02.2017)
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Respiratory complications of organophosphorus nerve agent and insecticide poisoning. Implications for respiratory and critical care
Hulse, Elspeth J, Davies, James O J, Simpson, A John, Sciuto, Alfred M, Eddleston, Michael
Published in American journal of respiratory and critical care medicine (15.12.2014)
Published in American journal of respiratory and critical care medicine (15.12.2014)
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Genetic dissection of the α-globin super-enhancer in vivo
Hay, Deborah, Hughes, Jim R, Babbs, Christian, Davies, James O J, Graham, Bryony J, Hanssen, Lars, Kassouf, Mira T, Marieke Oudelaar, A Marieke, Sharpe, Jacqueline A, Suciu, Maria C, Telenius, Jelena, Williams, Ruth, Rode, Christina, Li, Pik-Shan, Pennacchio, Len A, Sloane-Stanley, Jacqueline A, Ayyub, Helena, Butler, Sue, Sauka-Spengler, Tatjana, Gibbons, Richard J, Smith, Andrew J H, Wood, William G, Higgs, Douglas R
Published in Nature genetics (01.08.2016)
Published in Nature genetics (01.08.2016)
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Unlinking an lncRNA from Its Associated cis Element
Paralkar, Vikram R., Taborda, Cristian C., Huang, Peng, Yao, Yu, Kossenkov, Andrew V., Prasad, Rishi, Luan, Jing, Davies, James O.J., Hughes, Jim R., Hardison, Ross C., Blobel, Gerd A., Weiss, Mitchell J.
Published in Molecular cell (07.04.2016)
Published in Molecular cell (07.04.2016)
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