Naturally Occurring Off-Switches for CRISPR-Cas9
Pawluk, April, Amrani, Nadia, Zhang, Yan, Garcia, Bianca, Hidalgo-Reyes, Yurima, Lee, Jooyoung, Edraki, Alireza, Shah, Megha, Sontheimer, Erik J., Maxwell, Karen L., Davidson, Alan R.
Published in Cell (15.12.2016)
Published in Cell (15.12.2016)
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Journal Article
Prophages mediate defense against phage infection through diverse mechanisms
Bondy-Denomy, Joseph, Qian, Jason, Westra, Edze R, Buckling, Angus, Guttman, David S, Davidson, Alan R, Maxwell, Karen L
Published in The ISME Journal (01.12.2016)
Published in The ISME Journal (01.12.2016)
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Journal Article
The Discovery, Mechanisms, and Evolutionary Impact of Anti-CRISPRs
Borges, Adair L, Davidson, Alan R, Bondy-Denomy, Joseph
Published in Annual review of virology (29.09.2017)
Published in Annual review of virology (29.09.2017)
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Journal Article
Foreign DNA acquisition by the I-F CRISPR-Cas system requires all components of the interference machinery
Vorontsova, Daria, Datsenko, Kirill A, Medvedeva, Sofia, Bondy-Denomy, Joseph, Savitskaya, Ekaterina E, Pougach, Ksenia, Logacheva, Maria, Wiedenheft, Blake, Davidson, Alan R, Severinov, Konstantin, Semenova, Ekaterina
Published in Nucleic acids research (15.12.2015)
Published in Nucleic acids research (15.12.2015)
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Journal Article
Anti-CRISPR AcrIF9 functions by inducing the CRISPR–Cas complex to bind DNA non-specifically
Lu, Wang-Ting, Trost, Chantel N, Müller-Esparza, Hanna, Randau, Lennart, Davidson, Alan R
Published in Nucleic acids research (06.04.2021)
Published in Nucleic acids research (06.04.2021)
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Journal Article
The phage tail tape measure protein, an inner membrane protein and a periplasmic chaperone play connected roles in the genome injection process of E. coli phage HK97
Cumby, Nichole, Reimer, Kelly, Mengin‐Lecreulx, Dominique, Davidson, Alan R., Maxwell, Karen L.
Published in Molecular microbiology (01.05.2015)
Published in Molecular microbiology (01.05.2015)
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Journal Article
A new group of phage anti-CRISPR genes inhibits the type I-E CRISPR-Cas system of Pseudomonas aeruginosa
Pawluk, April, Bondy-Denomy, Joseph, Cheung, Vivian H W, Maxwell, Karen L, Davidson, Alan R
Published in mBio (15.04.2014)
Published in mBio (15.04.2014)
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Journal Article
Anti-phage defence through inhibition of virion assembly
Patel, Pramalkumar H, Taylor, Véronique L, Zhang, Chi, Getz, Landon J, Fitzpatrick, Alexa D, Davidson, Alan R, Maxwell, Karen L
Published in Nature communications (22.02.2024)
Published in Nature communications (22.02.2024)
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Journal Article
The solution structure of an anti-CRISPR protein
Maxwell, Karen L, Garcia, Bianca, Bondy-Denomy, Joseph, Bona, Diane, Hidalgo-Reyes, Yurima, Davidson, Alan R
Published in Nature communications (11.10.2016)
Published in Nature communications (11.10.2016)
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Journal Article
Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins
Lee, Jooyoung, Mir, Aamir, Edraki, Alireza, Garcia, Bianca, Amrani, Nadia, Lou, Hannah E, Gainetdinov, Ildar, Pawluk, April, Ibraheim, Raed, Gao, Xin D, Liu, Pengpeng, Davidson, Alan R, Maxwell, Karen L, Sontheimer, Erik J
Published in mBio (04.12.2018)
Published in mBio (04.12.2018)
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Journal Article
HNH proteins are a widespread component of phage DNA packaging machines
Kala, Smriti, Cumby, Nichole, Sadowski, Paul D., Hyder, Batool Zafar, Kanelis, Voula, Davidson, Alan R., Maxwell, Karen L.
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2014)
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Journal Article
AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex
Hirschi, Marscha, Lu, Wang-Ting, Santiago-Frangos, Andrew, Wilkinson, Royce, Golden, Sarah M, Davidson, Alan R, Lander, Gabriel C, Wiedenheft, Blake
Published in Nature communications (01.06.2020)
Published in Nature communications (01.06.2020)
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Journal Article
Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
Thavalingam, Annoj, Cheng, Zhi, Garcia, Bianca, Huang, Xue, Shah, Megha, Sun, Wei, Wang, Min, Harrington, Lucas, Hwang, Sungwon, Hidalgo-Reyes, Yurima, Sontheimer, Erik J, Doudna, Jennifer, Davidson, Alan R, Moraes, Trevor F, Wang, Yanli, Maxwell, Karen L
Published in Nature communications (26.06.2019)
Published in Nature communications (26.06.2019)
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Journal Article
phage λ major tail protein structure reveals a common evolution for long-tailed phages and the type VI bacterial secretion system
Pell, Lisa G, Kanelis, Voula, Donaldson, Logan W, Lynne Howell, P, Davidson, Alan R
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
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Journal Article
Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein
Pawluk, April, Shah, Megha, Mejdani, Marios, Calmettes, Charles, Moraes, Trevor F, Davidson, Alan R, Maxwell, Karen L
Published in mBio (12.12.2017)
Published in mBio (12.12.2017)
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Journal Article
Bacteriophage HK97 gp15 Moron Element Encodes a Novel Superinfection Exclusion Protein
Cumby, Nichole, Edwards, Aled M, Davidson, Alan R, Maxwell, Karen L
Published in Journal of Bacteriology (01.09.2012)
Published in Journal of Bacteriology (01.09.2012)
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