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Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2014)
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Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors
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Published in ACS medicinal chemistry letters (14.12.2017)
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Published in PloS one (11.01.2013)
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Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations
Birkinshaw, Richard W., Gong, Jia-nan, Luo, Cindy S., Lio, Daisy, White, Christine A., Anderson, Mary Ann, Blombery, Piers, Lessene, Guillaume, Majewski, Ian J., Thijssen, Rachel, Roberts, Andrew W., Huang, David C. S., Colman, Peter M., Czabotar, Peter E.
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MCMV-mediated inhibition of the pro-apoptotic Bak protein is required for optimal in vivo replication
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Published in PLoS pathogens (01.02.2013)
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Schwickart, Martin, Dornan, David, Huang, David C. S, Liu, Jinfeng, Lill, Jennie R, Maecker, Heather, Bazan, Fernando, Huang, XiaoDong, Yue, Peng, French, Dorothy M, Eastham-Anderson, Jeffrey, Dixit, Vishva M, Ferrando, Ronald, O'Rourke, Karen
Published in Nature (London) (07.01.2010)
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The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism
Anderson, Mary Ann, Deng, Jing, Seymour, John F., Tam, Constantine, Kim, Su Young, Fein, Joshua, Yu, Lijian, Brown, Jennifer R., Westerman, David, Si, Eric G., Majewski, Ian J., Segal, David, Heitner Enschede, Sari L., Huang, David C.S., Davids, Matthew S., Letai, Anthony, Roberts, Andrew W.
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Khaw, Seong Lin, Suryani, Santi, Evans, Kathryn, Richmond, Jennifer, Robbins, Alissa, Kurmasheva, Raushan T., Billups, Catherine A., Erickson, Stephen W., Guo, Yuelong, Houghton, Peter J., Smith, Malcolm A., Carol, Hernan, Roberts, Andrew W., Huang, David C.S., Lock, Richard B.
Published in Blood (08.09.2016)
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IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos
Fedele, Pasquale L., Willis, Simon N., Liao, Yang, Low, Michael S., Rautela, Jai, Segal, David H., Gong, Jia-Nan, Huntington, Nicholas D., Shi, Wei, Huang, David C.S., Grigoriadis, George, Tellier, Julie, Nutt, Stephen L.
Published in Blood (15.11.2018)
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Bcl-xL–inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets
Schoenwaelder, Simone M., Jarman, Kate E., Gardiner, Elizabeth E., Hua, My, Qiao, Jianlin, White, Michael J., Josefsson, Emma C., Alwis, Imala, Ono, Akiko, Willcox, Abbey, Andrews, Robert K., Mason, Kylie D., Salem, Hatem H., Huang, David C.S., Kile, Benjamin T., Roberts, Andrew W., Jackson, Shaun P.
Published in Blood (11.08.2011)
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Djajawi, Tirta Mario, Liu, Lei, Gong, Jia-nan, Huang, Allan Shuai, Luo, Ming-jie, Xu, Zhen, Okamoto, Toru, Call, Melissa J., Huang, David C. S., van Delft, Mark F.
Published in Cell death and differentiation (01.08.2020)
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NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression
Ju, Junyi, Chen, Aiping, Deng, Yexuan, Liu, Ming, Wang, Ying, Wang, Yadong, Nie, Min, Wang, Chao, Ding, Hong, Yao, Bing, Gui, Tao, Li, Xinyu, Xu, Zhen, Ma, Chi, Song, Yong, Kvansakul, Marc, Zen, Ke, Zhang, Chen-Yu, Luo, Cheng, Fang, Ming, Huang, David C. S., Allis, C. David, Tan, Renxiang, Zeng, Changjiang Kathy, Wei, Jiwu, Zhao, Quan
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Mitochondrial E3 ubiquitin ligase MARCHF5 controls BAK apoptotic activity independently of BH3-only proteins
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Published in Cell death and differentiation (01.03.2023)
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Venetoclax in Patients with Previously Treated Chronic Lymphocytic Leukemia
Roberts, Andrew W, Stilgenbauer, Stephan, Seymour, John F, Huang, David C S
Published in Clinical cancer research (15.08.2017)
Published in Clinical cancer research (15.08.2017)
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