Severe malarial anemia: innate immunity and pathogenesis
Perkins, Douglas J, Were, Tom, Davenport, Gregory C, Kempaiah, Prakasha, Hittner, James B, Ong'echa, John Michael
Published in International journal of biological sciences (01.01.2011)
Published in International journal of biological sciences (01.01.2011)
Get full text
Journal Article
MIF (Macrophage Migration Inhibitory Factor) Promoter Polymorphisms and Susceptibility to Severe Malarial Anemia
Awandare, Gordon A., Martinson, Jeremy J., Were, Tom, Ouma, Collins, Davenport, Gregory C., Ong’echa, John M., Wang, Wenkui, Leng, Lin, Ferrell, Robert E., Bucala, Richard, Perkins, Douglas J.
Published in The Journal of infectious diseases (15.08.2009)
Published in The Journal of infectious diseases (15.08.2009)
Get full text
Journal Article
Reduced Parasite Burden in Children with Falciparum Malaria and Bacteremia Coinfections: Role of Mediators of Inflammation
Ongecha, John M., Perkins, Douglas J., Kempaiah, Prakasha, Hengartner, Nicolas W., Fenimore, Paul W., Mukundan, Harshini, Karim, Zachary, Otieno, Vincent, Hittner, James B., Davenport, Gregory C., McMahon, Benjamin H.
Published in Mediators of inflammation (01.01.2016)
Published in Mediators of inflammation (01.01.2016)
Get full text
Journal Article
Role of Monocyte-Acquired Hemozoin in Suppression of Macrophage Migration Inhibitory Factor in Children with Severe Malarial Anemia
Awandare, Gordon A, Ouma, Yamo, Ouma, Collins, Were, Tom, Otieno, Richard, Keller, Christopher C, Davenport, Gregory C, Hittner, James B, Vulule, John, Ferrell, Robert, Ong'echa, John M, Perkins, Douglas J
Published in Infection and Immunity (01.01.2007)
Published in Infection and Immunity (01.01.2007)
Get full text
Journal Article
Polymorphic Variability in the Interleukin (IL)-1β Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1β Production
Ouma, Collins, Davenport, Gregory C., Awandare, Gordon A., Keller, Christopher C., Were, Tom, Otieno, Michael F., Vulule, John M., Martinson, Jeremy, Ong'echa, John M., Ferrell, Robert E., Perkins, Douglas J.
Published in The Journal of infectious diseases (15.10.2008)
Published in The Journal of infectious diseases (15.10.2008)
Get full text
Journal Article
Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children
Ouma, Collins, Davenport, Gregory C., Garcia, Steven, Kempaiah, Prakasha, Chaudhary, Ateefa, Were, Tom, Anyona, Samuel B., Raballah, Evans, Konah, Stephen N., Hittner, James B., Vulule, John M., Ong’echa, John M., Perkins, Douglas J.
Published in Human genetics (01.02.2012)
Published in Human genetics (01.02.2012)
Get full text
Journal Article
Functional Promoter Haplotypes of Interleukin-18 Condition Susceptibility to Severe Malarial Anemia and Childhood Mortality
ANYONA, Samuel B, KEMPAIAH, Prakasha, ONG'ECHA, John M, PERKINS, Douglas J, RABALLAH, Evans, OUMA, Collins, WERE, Tom, DAVENPORT, Gregory C, KONAH, Stephen N, VULULE, John M, HITTNER, James B, GICHUKI, Charity W
Published in Infection and Immunity (01.12.2011)
Published in Infection and Immunity (01.12.2011)
Get full text
Journal Article
Novel Functional Variant in the Stem Cell Growth Factor Promoter Protects against Severe Malarial Anemia
Ouma, Collins, Keller, Christopher C, Davenport, Gregory C, Were, Tom, Konah, Stephen, Otieno, Michael F, Hittner, James B, Vulule, John M, Martinson, Jeremy, Ong'echa, John M, Ferrell, Robert E, Perkins, Douglas J
Published in Infection and Immunity (01.01.2010)
Published in Infection and Immunity (01.01.2010)
Get full text
Journal Article
Suppression of a Novel Hematopoietic Mediator in Children with Severe Malarial Anemia
Keller, Christopher C, Ouma, Collins, Ouma, Yamo, Awandare, Gordon A, Davenport, Gregory C, Were, Tom, Hittner, James B, Vulule, John M, Ong'echa, John M, Perkins, Douglas J
Published in Infection and Immunity (01.09.2009)
Published in Infection and Immunity (01.09.2009)
Get full text
Journal Article
Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production
Ouma, Collins, Davenport, Gregory C, Were, Tom, Otieno, Michael F, Hittner, James B, Vulule, John M, Martinson, Jeremy, Ong'echa, John M, Ferrell, Robert E, Perkins, Douglas J
Published in Human genetics (01.12.2008)
Published in Human genetics (01.12.2008)
Get full text
Journal Article
Clinical predictors of severe malarial anaemia in a holoendemic Plasmodium falciparum transmission area
Novelli, Enrico M., Hittner, James B., Davenport, Gregory C., Ouma, Collins, Were, Tom, Obaro, Stephen, Kaplan, Sandra, Ong’echa, John M., Perkins, Douglas J.
Published in British journal of haematology (01.06.2010)
Published in British journal of haematology (01.06.2010)
Get full text
Journal Article
Suppressed circulating bicyclo-PGE2 levels and leukocyte COX-2 transcripts in children co-infected with P. falciparum malaria and HIV-1 or bacteremia
Anyona, Samuel B., Kempaiah, Prakasha, Davenport, Gregory C., Vulule, John M., Hittner, James B., Ong’echa, John M., Perkins, Douglas J.
Published in Biochemical and biophysical research communications (12.07.2013)
Published in Biochemical and biophysical research communications (12.07.2013)
Get full text
Journal Article
Relationship between inflammatory mediator patterns and anemia in HIV-1 positive and exposed children with Plasmodium falciparum malaria
Davenport, Gregory C., Hittner, James B., Were, Tom, Ong'echa, John M., Perkins, Douglas J.
Published in American journal of hematology (01.07.2012)
Published in American journal of hematology (01.07.2012)
Get full text
Journal Article
Hematological predictors of increased severe anemia in Kenyan children coinfected with Plasmodium falciparum and HIV‐1
Davenport, Gregory C., Ouma, Collins, Hittner, James B., Were, Tom, Ouma, Yamo, Ong'echa, John M., Perkins, Douglas J.
Published in American journal of hematology (01.04.2010)
Published in American journal of hematology (01.04.2010)
Get full text
Journal Article
Reduced interferon (IFN)-α conditioned by IFNA2 (−173) and IFNA8 (−884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality
Kempaiah, Prakasha, Anyona, Samuel B., Raballah, Evans, Davenport, Gregory C., Were, Tom, Hittner, James B., Ong’echa, John M., Perkins, Douglas J.
Published in Human genetics (01.08.2012)
Published in Human genetics (01.08.2012)
Get full text
Journal Article
Reduced systemic bicyclo-prostaglandin-E2 and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia
Anyona, Samuel B., Kempaiah, Prakasha, Raballah, Evans, Davenport, Gregory C., Were, Tom, Konah, Stephen N., Vulule, John M., Hittner, James B., Gichuki, Charity W., Ong'echa, John M., Perkins, Douglas J.
Published in American journal of hematology (01.08.2012)
Published in American journal of hematology (01.08.2012)
Get full text
Journal Article
Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism
Were, Tom, Davenport, Gregory C., Yamo, Emmanuel O., Hittner, James B., Awandare, Gordon A., Otieno, Michael F., Ouma, Collins, Orago, Alloys S.S., Vulule, John M., Ong'echa, John M., Perkins, Douglas J.
Published in Microbes and infection (01.07.2009)
Published in Microbes and infection (01.07.2009)
Get full text
Journal Article
Suppression of Prostaglandin E2 by Malaria Parasite Products and Antipyretics Promotes Overproduction of Tumor Necrosis Factor–α: Association with the Pathogenesis of Childhood Malarial Anemia
Keller, Christopher C., Davenport, Gregory C., Dickman, Katherine R., Hittner, James B., Kaplan, Sandra S., Weinberg, J. Brice, Kremsner, Peter G., Perkins, Douglas J.
Published in The Journal of infectious diseases (15.05.2006)
Published in The Journal of infectious diseases (15.05.2006)
Get full text
Journal Article
Functional haplotypes of Fc gamma
Ouma, Collins, Davenport, Gregory C, Garcia, Steven, Kempaiah, Prakasha, Chaudhary, Ateefa, Were, Tom, Anyona, Samuel B
Published in Human genetics (01.02.2012)
Published in Human genetics (01.02.2012)
Get full text
Journal Article