Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition
Sundar, Raghav, Huang, Kie-Kyon, Kumar, Vikrant, Ramnarayanan, Kalpana, Demircioglu, Deniz, Her, Zhisheng, Ong, Xuewen, Bin Adam Isa, Zul Fazreen, Xing, Manjie, Tan, Angie Lay-Keng, Tai, David Wai Meng, Choo, Su Pin, Zhai, Weiwei, Lim, Jia Qi, Das Thakur, Meghna, Molinero, Luciana, Cha, Edward, Fasso, Marcella, Niger, Monica, Pietrantonio, Filippo, Lee, Jeeyun, Jeyasekharan, Anand D, Qamra, Aditi, Patnala, Radhika, Fabritius, Arne, De Simone, Mark, Yeong, Joe, Ng, Cedric Chuan Young, Rha, Sun Young, Narita, Yukiya, Muro, Kei, Guo, Yu Amanda, Skanderup, Anders Jacobsen, So, Jimmy Bok Yan, Yong, Wei Peng, Chen, Qingfeng, Göke, Jonathan, Tan, Patrick
Published in Gut (01.07.2022)
Published in Gut (01.07.2022)
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BRIM‐P: A phase I, open‐label, multicenter, dose‐escalation study of vemurafenib in pediatric patients with surgically incurable, BRAF mutation‐positive melanoma
Chisholm, Julia C., Suvada, Jozef, Dunkel, Ira J., Casanova, Michela, Zhang, Weijiang, Ritchie, Natasha, Choi, YounJeong, Park, Jane, Das Thakur, Meghna, Simko, Stephen, Wan Rachel Tam, Nga, Ferrari, Andrea
Published in Pediatric blood & cancer (01.05.2018)
Published in Pediatric blood & cancer (01.05.2018)
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Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B
Daemen, Anneleen, Udyavar, Akshata R, Sandmann, Thomas, Li, Congfen, Bosch, Linda J W, O'Gorman, William, Li, Yijin, Au-Yeung, Amelia, Takahashi, Chikara, Kabbarah, Omar, Bourgon, Richard, Hegde, Priti, Bais, Carlos, Das Thakur, Meghna
Published in PloS one (31.12.2021)
Published in PloS one (31.12.2021)
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Journal Article
Ligand-independent EPHA2 signaling drives the adoption of a targeted therapy-mediated metastatic melanoma phenotype
Paraiso, Kim H T, Das Thakur, Meghna, Fang, Bin, Koomen, John M, Fedorenko, Inna V, John, Jobin K, Tsao, Hensin, Flaherty, Keith T, Sondak, Vernon K, Messina, Jane L, Pasquale, Elena B, Villagra, Alejandro, Rao, Uma N, Kirkwood, John M, Meier, Friedegund, Sloot, Sarah, Gibney, Geoffrey T, Stuart, Darrin, Tawbi, Hussein, Smalley, Keiran S M
Published in Cancer discovery (01.03.2015)
Published in Cancer discovery (01.03.2015)
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Peripheral T cell expansion predicts tumour infiltration and clinical response
Wu, Thomas D, Madireddi, Shravan, de Almeida, Patricia E, Banchereau, Romain, Chen, Ying-Jiun J, Chitre, Avantika S, Chiang, Eugene Y, Iftikhar, Hina, O'Gorman, William E, Au-Yeung, Amelia, Takahashi, Chikara, Goldstein, Leonard D, Poon, Chungkee, Keerthivasan, Shilpa, de Almeida Nagata, Denise E, Du, Xiangnan, Lee, Hyang-Mi, Banta, Karl L, Mariathasan, Sanjeev, Das Thakur, Meghna, Huseni, Mahrukh A, Ballinger, Marcus, Estay, Ivette, Caplazi, Patrick, Modrusan, Zora, Delamarre, Lélia, Mellman, Ira, Bourgon, Richard, Grogan, Jane L
Published in Nature (London) (01.03.2020)
Published in Nature (London) (01.03.2020)
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Journal Article
Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance
Das Thakur, Meghna, Salangsang, Fernando, Landman, Allison S, Sellers, William R, Pryer, Nancy K, Levesque, Mitchell P, Dummer, Reinhard, McMahon, Martin, Stuart, Darrin D
Published in Nature (London) (14.02.2013)
Published in Nature (London) (14.02.2013)
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Journal Article
Metallurgical changes of cryogenically treated Coated Carbide (KC-9225) and its performance during wet machining of Austenitic Stainless Steel - 310
Chaudhury, Meghna Das, Raju, Subramanian, Anbarasu
Published in IOP conference series. Materials Science and Engineering (01.04.2019)
Published in IOP conference series. Materials Science and Engineering (01.04.2019)
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Journal Article
Ajuba LIM Proteins Are Negative Regulators of the Hippo Signaling Pathway
Das Thakur, Meghna, Feng, Yunfeng, Jagannathan, Radhika, Seppa, Midori J., Skeath, James B., Longmore, Gregory D.
Published in Current biology (13.04.2010)
Published in Current biology (13.04.2010)
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Journal Article
Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial
Mackay, Alan, Burford, Anna, Molinari, Valeria, Jones, David T.W., Izquierdo, Elisa, Brouwer-Visser, Jurriaan, Giangaspero, Felice, Haberler, Christine, Pietsch, Torsten, Jacques, Thomas S., Figarella-Branger, Dominique, Rodriguez, Daniel, Morgan, Paul S., Raman, Pichai, Waanders, Angela J., Resnick, Adam C., Massimino, Maura, Garrè, Maria Luisa, Smith, Helen, Capper, David, Pfister, Stefan M., Würdinger, Thomas, Tam, Rachel, Garcia, Josep, Thakur, Meghna Das, Vassal, Gilles, Grill, Jacques, Jaspan, Tim, Varlet, Pascale, Jones, Chris
Published in Cancer cell (14.05.2018)
Published in Cancer cell (14.05.2018)
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Journal Article
Pan‐cancer population pharmacokinetics and exposure‐safety and ‐efficacy analyses of atezolizumab in patients with high tumor mutational burden
Shemesh, Colby S., Chan, Phyllis, Legrand, Fatema A., Shames, David S., Das Thakur, Meghna, Shi, Jane, Bailey, Lorna, Vadhavkar, Shweta, He, Xian, Zhang, Wei, Bruno, René
Published in Pharmacology research & perspectives (01.12.2020)
Published in Pharmacology research & perspectives (01.12.2020)
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Clinical efficacy of atezolizumab plus bevacizumab and chemotherapy in KRAS-mutated non-small cell lung cancer with STK11, KEAP1, or TP53 comutations: subgroup results from the phase III IMpower150 trial
West, Howard Jack, McCleland, Mark, Cappuzzo, Federico, Reck, Martin, Mok, Tony SK, Jotte, Robert M, Nishio, Makoto, Kim, Eugene, Morris, Stefanie, Zou, Wei, Shames, David, Das Thakur, Meghna, Shankar, Geetha, Socinski, Mark A
Published in Journal for immunotherapy of cancer (01.02.2022)
Published in Journal for immunotherapy of cancer (01.02.2022)
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Journal Article
Clinical and exploratory biomarker findings from the MODUL trial (Cohorts 1, 3 and 4) of biomarker-driven maintenance therapy for metastatic colorectal cancer
Ducreux, Michel, Tabernero, Josep, Grothey, Axel, Arnold, Dirk, O'Dwyer, Peter J., Gilberg, Frank, Abbas, Alexander, Thakur, Meghna Das, Prizant, Hen, Irahara, Natsumi, Tahiri, Anila, Schmoll, Hans-Joachim, Van Cutsem, Eric, de Gramont, Aimery
Published in European journal of cancer (1990) (01.05.2023)
Published in European journal of cancer (1990) (01.05.2023)
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Journal Article
Immune contexture of paediatric cancers
Thakur, Meghna Das, Franz, Carl J., Brennan, Laura, Brouwer-Visser, Jurriaan, Tam, Rachel, Korski, Konstanty, Koeppen, Hartmut, Ziai, James, Babitzki, Galina, Ranchere-Vince, Dominique, Vasiljevic, Alexandre, Dijoud, Frédérique, Marec-Bérard, Perrine, Rochet, Isabelle, Cannarile, Michael A., Marabelle, Aurélien
Published in European journal of cancer (1990) (01.07.2022)
Published in European journal of cancer (1990) (01.07.2022)
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CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials
Segal, Neil H, Melero, Ignacio, Moreno, Victor, Steeghs, Neeltje, Marabelle, Aurelien, Rohrberg, Kristoffer, Rodriguez-Ruiz, Maria E, Eder, Joseph P, Eng, Cathy, Manji, Gulam A, Waterkamp, Daniel, Leutgeb, Barbara, Bouseida, Said, Flinn, Nick, Das Thakur, Meghna, Elze, Markus C, Koeppen, Hartmut, Jamois, Candice, Martin-Facklam, Meret, Lieu, Christopher H, Calvo, Emiliano, Paz-Ares, Luis, Tabernero, Josep, Argilés, Guillem
Published in Nature communications (15.05.2024)
Published in Nature communications (15.05.2024)
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Novel Anti-LY6G6D/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Colorectal Cancer
Wang, Peiyin, Sun, Liping L, Clark, Robyn, Hristopoulos, Maria, Chiu, Cecilia P C, Dillon, Michael, Lin, WeiYu, Lo, Amy A, Chalsani, Sreedevi, Das Thakur, Meghna, Zimmerman Savill, Kristin M, Rougé, Lionel, Lupardus, Patrick, Piskol, Robert, Husain, Bushra, Ellerman, Diego, Shivva, Vittal, Leong, Steven R, Ovacik, Meric, Totpal, Klara, Wu, Yan, Spiess, Christoph, Lee, Genee, Leipold, Douglas D, Polson, Andrew G
Published in Molecular cancer therapeutics (01.06.2022)
Published in Molecular cancer therapeutics (01.06.2022)
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A Multifunctional Lentiviral-Based Gene Knockdown with Concurrent Rescue that Controls for Off-Target Effects of RNAi
Feng, Yunfeng, Nie, Linghu, Thakur, Meghna Das, Su, Qin, Chi, Zhenfen, Zhao, Yongliang, Longmore, Gregory D.
Published in Genomics, proteomics & bioinformatics (01.12.2010)
Published in Genomics, proteomics & bioinformatics (01.12.2010)
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