A role for tubular Na + /H + exchanger NHE3 in the natriuretic effect of the SGLT2 inhibitor empagliflozin
Onishi, Akira, Fu, Yiling, Patel, Rohit, Darshi, Manjula, Crespo-Masip, Maria, Huang, Winnie, Song, Panai, Freeman, Brent, Kim, Young Chul, Soleimani, Manoocher, Sharma, Kumar, Thomson, Scott Culver, Vallon, Volker
Published in American journal of physiology. Renal physiology (01.10.2020)
Published in American journal of physiology. Renal physiology (01.10.2020)
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Journal Article
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
Garrett-Bakelman, Francine E, Darshi, Manjula, Green, Stefan J, Gur, Ruben C, Lin, Ling, Macias, Brandon R, McKenna, Miles J, Meydan, Cem, Mishra, Tejaswini, Nasrini, Jad, Piening, Brian D, Rizzardi, Lindsay F, Sharma, Kumar, Siamwala, Jamila H, Taylor, Lynn, Vitaterna, Martha Hotz, Afkarian, Maryam, Afshinnekoo, Ebrahim, Ahadi, Sara, Ambati, Aditya, Arya, Maneesh, Bezdan, Daniela, Callahan, Colin M, Chen, Songjie, Choi, Augustine M K, Chlipala, George E, Contrepois, Kévin, Covington, Marisa, Crucian, Brian E, De Vivo, Immaculata, Dinges, David F, Ebert, Douglas J, Feinberg, Jason I, Gandara, Jorge A, George, Kerry A, Goutsias, John, Grills, George S, Hargens, Alan R, Heer, Martina, Hillary, Ryan P, Hoofnagle, Andrew N, Hook, Vivian Y H, Jenkinson, Garrett, Jiang, Peng, Keshavarzian, Ali, Laurie, Steven S, Lee-McMullen, Brittany, Lumpkins, Sarah B, MacKay, Matthew, Maienschein-Cline, Mark G, Melnick, Ari M, Moore, Tyler M, Nakahira, Kiichi, Patel, Hemal H, Pietrzyk, Robert, Rao, Varsha, Saito, Rintaro, Salins, Denis N, Schilling, Jan M, Sears, Dorothy D, Sheridan, Caroline K, Stenger, Michael B, Tryggvadottir, Rakel, Urban, Alexander E, Vaisar, Tomas, Van Espen, Benjamin, Zhang, Jing, Ziegler, Michael G, Zwart, Sara R, Charles, John B, Kundrot, Craig E, Scott, Graham B I, Bailey, Susan M, Basner, Mathias, Feinberg, Andrew P, Lee, Stuart M C, Mason, Christopher E, Mignot, Emmanuel, Rana, Brinda K, Smith, Scott M, Snyder, Michael P, Turek, Fred W
Published in Science (American Association for the Advancement of Science) (12.04.2019)
Published in Science (American Association for the Advancement of Science) (12.04.2019)
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Journal Article
Metabolomics in Diabetic Kidney Disease: Unraveling the Biochemistry of a Silent Killer
Darshi, Manjula, Van Espen, Benjamin, Sharma, Kumar
Published in American journal of nephrology (01.01.2016)
Published in American journal of nephrology (01.01.2016)
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Journal Article
Effect of renal tubule-specific knockdown of the Na + /H + exchanger NHE3 in Akita diabetic mice
Onishi, Akira, Fu, Yiling, Darshi, Manjula, Crespo-Masip, Maria, Huang, Winnie, Song, Panai, Patel, Rohit, Kim, Young Chul, Nespoux, Josselin, Freeman, Brent, Soleimani, Manoocher, Thomson, Scott, Sharma, Kumar, Vallon, Volker
Published in American journal of physiology. Renal physiology (01.08.2019)
Published in American journal of physiology. Renal physiology (01.08.2019)
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Journal Article
ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function
Darshi, Manjula, Mendiola, Vincent L., Mackey, Mason R., Murphy, Anne N., Koller, Antonius, Perkins, Guy A., Ellisman, Mark H., Taylor, Susan S.
Published in The Journal of biological chemistry (28.01.2011)
Published in The Journal of biological chemistry (28.01.2011)
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Journal Article
Uniform nomenclature for the mitochondrial contact site and cristae organizing system
Pfanner, Nikolaus, van der Laan, Martin, Amati, Paolo, Capaldi, Roderick A, Caudy, Amy A, Chacinska, Agnieszka, Darshi, Manjula, Deckers, Markus, Hoppins, Suzanne, Icho, Tateo, Jakobs, Stefan, Ji, Jianguo, Kozjak-Pavlovic, Vera, Meisinger, Chris, Odgren, Paul R, Park, Sang Ki, Rehling, Peter, Reichert, Andreas S, Sheikh, M Saeed, Taylor, Susan S, Tsuchida, Nobuo, van der Bliek, Alexander M, van der Klei, Ida J, Weissman, Jonathan S, Westermann, Benedikt, Zha, Jiping, Neupert, Walter, Nunnari, Jodi
Published in The Journal of cell biology (31.03.2014)
Published in The Journal of cell biology (31.03.2014)
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Journal Article
Metabolomics and Gene Expression Analysis Reveal Down-regulation of the Citric Acid (TCA) Cycle in Non-diabetic CKD Patients
Hallan, Stein, Afkarian, Maryam, Zelnick, Leila R., Kestenbaum, Bryan, Sharma, Shoba, Saito, Rintaro, Darshi, Manjula, Barding, Gregory, Raftery, Daniel, Ju, Wenjun, Kretzler, Matthias, Sharma, Kumar, de Boer, Ian H.
Published in EBioMedicine (01.12.2017)
Published in EBioMedicine (01.12.2017)
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Journal Article
Sub-mitochondrial localization of the genetic-tagged mitochondrial intermembrane space-bridging components Mic19, Mic60 and Sam50
Sastri, Mira, Darshi, Manjula, Mackey, Mason, Ramachandra, Ranjan, Ju, Saeyeon, Phan, Sebastien, Adams, Stephen, Stein, Kathryn, Douglas, Christopher R, Kim, Jiwan John, Ellisman, Mark H, Taylor, Susan S, Perkins, Guy A
Published in Journal of cell science (01.10.2017)
Published in Journal of cell science (01.10.2017)
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Journal Article
Mass Spectrometry Imaging Reveals Elevated Glomerular ATP/AMP in Diabetes/obesity and Identifies Sphingomyelin as a Possible Mediator
Miyamoto, Satoshi, Hsu, Cheng-Chih, Hamm, Gregory, Darshi, Manjula, Diamond-Stanic, Maggie, Declèves, Anne-Emilie, Slater, Larkin, Pennathur, Subramaniam, Stauber, Jonathan, Dorrestein, Pieter C., Sharma, Kumar
Published in EBioMedicine (01.05.2016)
Published in EBioMedicine (01.05.2016)
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Journal Article
Crabtree effect in kidney proximal tubule cells via late-stage glycolytic intermediates
Darshi, Manjula, Tumova, Jana, Saliba, Afaf, Kim, Jiwan, Baek, Judy, Pennathur, Subramaniam, Sharma, Kumar
Published in iScience (21.04.2023)
Published in iScience (21.04.2023)
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Journal Article
Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications
Sas, Kelli M, Kayampilly, Pradeep, Byun, Jaeman, Nair, Viji, Hinder, Lucy M, Hur, Junguk, Zhang, Hongyu, Lin, Chengmao, Qi, Nathan R, Michailidis, George, Groop, Per-Henrik, Nelson, Robert G, Darshi, Manjula, Sharma, Kumar, Schelling, Jeffrey R, Sedor, John R, Pop-Busui, Rodica, Weinberg, Joel M, Soleimanpour, Scott A, Abcouwer, Steven F, Gardner, Thomas W, Burant, Charles F, Feldman, Eva L, Kretzler, Matthias, Brosius, 3rd, Frank C, Pennathur, Subramaniam
Published in JCI insight (22.09.2016)
Published in JCI insight (22.09.2016)
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Journal Article
Quantitative Proteomic and Functional Analysis of Liver Mitochondria from High Fat Diet (HFD) Diabetic Mice
Guo, Yurong, Darshi, Manjula, Ma, Yuliang, Perkins, Guy A., Shen, Zhouxin, Haushalter, Kristofer J., Saito, Rintaro, Chen, Ai, Lee, Yun Sok, Patel, Hemal H., Briggs, Steven P., Ellisman, Mark H., Olefsky, Jerrold M., Taylor, Susan S.
Published in Molecular & cellular proteomics (01.12.2013)
Published in Molecular & cellular proteomics (01.12.2013)
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Journal Article
Gut Microbial Changes in Diabetic db/db Mice and Recovery of Microbial Diversity upon Pirfenidone Treatment
Singh, Harinder, Miyamoto, Satoshi, Darshi, Manjula, Torralba, Manolito G., Kwon, Keehwan, Sharma, Kumar, Pieper, Rembert
Published in Microorganisms (Basel) (03.09.2020)
Published in Microorganisms (Basel) (03.09.2020)
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Journal Article
Mechanisms of cyclic AMP/protein kinase A- and glucocorticoid-mediated apoptosis using S49 lymphoma cells as a model system
Keshwani, Malik M., Kanter, Joan R., Ma, Yuliang, Wilderman, Andrea, Darshi, Manjula, Insel, Paul A., Taylor, Susan S.
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2015)
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Journal Article
kinase interacting protein (AKIP1) is a key regulator of cardiac stress
Sastri, Mira, Haushalter, Kristofer J, Panneerselvam, Mathivadhani, Chang, Philip, Fridolfsson, Heidi, Finley, J Cameron, Ng, Daniel, Schilling, Jan M, Miyanohara, Atsushi, Day, Michele E, Hakozaki, Hiro, Petrosyan, Susanna, Koller, Antonius, King, Charles C, Darshi, Manjula, Blumenthal, Donald K, Ali, Sameh Saad, Roth, David M, Patel, Hemal H, Taylor, Susan S
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2013)
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Journal Article
Identification of ChChd3 as a Novel Substrate of the cAMP-dependent Protein Kinase (PKA) Using an Analog-sensitive Catalytic Subunit
Schauble, Sharmin, King, Charles C., Darshi, Manjula, Koller, Antonius, Shah, Kavita, Taylor, Susan S.
Published in The Journal of biological chemistry (18.05.2007)
Published in The Journal of biological chemistry (18.05.2007)
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Journal Article
Identification of Circulating Metabolites to Predict Cardiorenal Outcomes in Patients with Type 2 Diabetes (T2D): TH-PO174
Hansen, Michael K., Darshi, Manjula, Kohler, Kristen, Tang, Owen, Figtree, Gemma
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study
Kwan, Brian, Fuhrer, Tobias, Zhang, Jing, Darshi, Manjula, Van Espen, Benjamin, Montemayor, Daniel, de Boer, Ian H., Dobre, Mirela, Hsu, Chi-yuan, Kelly, Tanika N., Raj, Dominic S., Rao, Panduranga S., Saraf, Santosh L., Scialla, Julia, Waikar, Sushrut S., Sharma, Kumar, Natarajan, Loki, Appel, Lawrence J., Feldman, Harold I., Go, Alan S., He, Jiang, Lash, James P., Rahman, Mahboob, Townsend, Raymond R.
Published in American journal of kidney diseases (01.10.2020)
Published in American journal of kidney diseases (01.10.2020)
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Journal Article