Supernatural T cells: genetic modification of T cells for cancer therapy
Kershaw, Michael H, Teng, Michele W. L, Smyth, Mark J, Darcy, Phillip K
Published in Nature Reviews: Immunology (01.12.2005)
Published in Nature Reviews: Immunology (01.12.2005)
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Journal Article
A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation
Ludford-Menting, Mandy J., Oliaro, Jane, Sacirbegovic, Faruk, Cheah, Eric T.-Y., Pedersen, Natalie, Thomas, Suzanne J., Pasam, Anupama, Iazzolino, Rosa, Dow, Lukas E., Waterhouse, Nigel J., Murphy, Amanda, Ellis, Sarah, Smyth, Mark J., Kershaw, Michael H., Darcy, Phillip K., Humbert, Patrick O., Russell, Sarah M.
Published in Immunity (Cambridge, Mass.) (01.06.2005)
Published in Immunity (Cambridge, Mass.) (01.06.2005)
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Journal Article
Induction of tumor-specific T cell memory by NK cell-mediated tumor rejection
Smyth, Mark J, Kelly, Janice M, Darcy, Phillip K, Markby, Jessica L, Godfrey, Dale I, Takeda, Kazuyoshi, Yagita, Hideo
Published in Nature immunology (01.01.2002)
Published in Nature immunology (01.01.2002)
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Journal Article
Adoptive Transfer of T Cells Modified with a Humanized Chimeric Receptor Gene Inhibits Growth of Lewis-Y-Expressing Tumors in Mice
Jennifer A. Westwood, Smyth, Mark J., Michele W. L. Teng, Maria Moeller, Trapani, Joseph A., Scott, Andrew M., Fiona E. Smyth, Glenn A. Cartwright, Barbara E. Power, Dirk Hönemann, H. Miles Prince, Phillip K. Darcy, Michael H. Kershaw
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2005)
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Journal Article
Cutting Edge: Tumor Rejection Mediated by NKG2D Receptor-Ligand Interaction Is Dependent upon Perforin
Hayakawa, Yoshihiro, Kelly, Janice M, Westwood, Jennifer A, Darcy, Phillip K, Diefenbach, Andreas, Raulet, David, Smyth, Mark J
Published in The Journal of immunology (1950) (15.11.2002)
Published in The Journal of immunology (1950) (15.11.2002)
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Journal Article
Adoptive transfer of gene-engineered CD4+ helper T cells induces potent primary and secondary tumor rejection
Moeller, Maria, Haynes, Nicole M., Kershaw, Michael H., Jackson, Jacob T., Teng, Michele W.L., Street, Shayna E., Cerutti, Loretta, Jane, Stephen M., Trapani, Joseph A., Smyth, Mark J., Darcy, Phillip K.
Published in Blood (01.11.2005)
Published in Blood (01.11.2005)
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Journal Article
Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors
Haynes, Nicole M., Trapani, Joseph A., Teng, Michèle W.L., Jackson, Jacob T., Cerruti, Loretta, Jane, Stephen M., Kershaw, Michael H., Smyth, Mark J., Darcy, Phillip K.
Published in Blood (01.11.2002)
Published in Blood (01.11.2002)
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Journal Article
Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux
Tainton, K M, Smyth, M J, Jackson, J T, Tanner, J E, Cerruti, L, Jane, S M, Darcy, P K, Johnstone, R W
Published in Cell death and differentiation (01.09.2004)
Published in Cell death and differentiation (01.09.2004)
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Journal Article
Gene Modification Strategies to Induce Tumor Immunity
Murphy, Amanda, Westwood, Jennifer A., Teng, Michele W.L., Moeller, Maria, Darcy, Phillip K., Kershaw, Michael H.
Published in Immunity (Cambridge, Mass.) (01.04.2005)
Published in Immunity (Cambridge, Mass.) (01.04.2005)
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Journal Article
The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene
Voskoboinik, Ilia, Thia, Marie-Claude, De Bono, Annette, Browne, Kylie, Cretney, Erika, Jackson, Jacob T, Darcy, Phillip K, Jane, Stephen M, Smyth, Mark J, Trapani, Joseph A
Published in The Journal of experimental medicine (20.09.2004)
Published in The Journal of experimental medicine (20.09.2004)
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Journal Article
Gene-Engineered T Cells as a Superior Adjuvant Therapy for Metastatic Cancer
Kershaw, Michael H, Jackson, Jacob T, Haynes, Nicole M, Teng, Michele W. L, Moeller, Maria, Hayakawa, Yoshihiro, Street, Shayna E, Cameron, Rachel, Tanner, Jane E, Trapani, Joseph A, Smyth, Mark J, Darcy, Phillip K
Published in The Journal of immunology (1950) (01.08.2004)
Published in The Journal of immunology (1950) (01.08.2004)
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Journal Article
Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma
Haynes, N M, Snook, M B, Trapani, J A, Cerruti, L, Jane, S M, Smyth, M J, Darcy, P K
Published in The Journal of immunology (1950) (01.01.2001)
Published in The Journal of immunology (1950) (01.01.2001)
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Journal Article
Rejection of Syngeneic Colon Carcinoma by CTLs Expressing Single-Chain Antibody Receptors Codelivering CD28 Costimulation
Haynes, Nicole M, Trapani, Joseph A, Teng, Michele W. L, Jackson, Jacob T, Cerruti, Loretta, Jane, Stephen M, Kershaw, Michael H, Smyth, Mark J, Darcy, Phillip K
Published in The Journal of immunology (1950) (15.11.2002)
Published in The Journal of immunology (1950) (15.11.2002)
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Journal Article
Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2
Cresswell, Kim S., Clarke, Christopher J.P., Jackson, Jacob T., Darcy, Phillip K., Trapani, Joseph A., Johnstone, Ricky W.
Published in Biochemical and biophysical research communications (14.01.2005)
Published in Biochemical and biophysical research communications (14.01.2005)
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Journal Article
Immunotherapy of cancer using systemically delivered gene-modified human T lymphocytes
Teng, Michele W L, Kershaw, Michael H, Moeller, Maria, Smyth, Mark J, Darcy, Phillip K
Published in Human gene therapy (01.07.2004)
Published in Human gene therapy (01.07.2004)
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Journal Article
Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth
Vincan, Elizabeth, Darcy, Phillip K., Smyth, Mark J., Ramsay, Robert G., Thompson, Erik W., Thomas, Robert J.S., Phillips, Wayne A.
Published in Differentiation (London) (01.04.2005)
Published in Differentiation (London) (01.04.2005)
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Journal Article
Redirected Perforin-Dependent Lysis of Colon Carcinoma by Ex Vivo Genetically Engineered CTL
Darcy, Phillip K, Haynes, Nicole M, Snook, Marie B, Trapani, Joseph A, Cerruti, Loretta, Jane, Stephen M, Smyth, Mark J
Published in The Journal of immunology (1950) (01.04.2000)
Published in The Journal of immunology (1950) (01.04.2000)
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Journal Article
A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells
Moeller, Maria, Haynes, Nicole M, Trapani, Joseph A, Teng, Michele W L, Jackson, Jacob T, Tanner, Jane E, Cerutti, Loretta, Jane, Stephen M, Kershaw, Michael H, Smyth, Mark J, Darcy, Phillip K
Published in Cancer gene therapy (01.05.2004)
Published in Cancer gene therapy (01.05.2004)
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