Sertoli Cell Number Defines and Predicts Germ and Leydig Cell Population Sizes in the Adult Mouse Testis
Rebourcet, Diane, Darbey, Annalucia, Monteiro, Ana, Soffientini, Ugo, Tsai, Yi Ting, Handel, Ian, Pitetti, Jean-Luc, Nef, Serge, Smith, Lee B, O’Shaughnessy, Peter J
Published in Endocrinology (Philadelphia) (01.09.2017)
Published in Endocrinology (Philadelphia) (01.09.2017)
Get full text
Journal Article
A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function
Gannon, Anne-Louise, Darbey, Annalucia L, Chensee, Grace, Lawrence, Ben M, O'Donnell, Liza, Kelso, Joanna, Reed, Natalie, Parameswaran, Shanmathi, Smith, Sarah, Smith, Lee B, Rebourcet, Diane
Published in International journal of molecular sciences (30.11.2022)
Published in International journal of molecular sciences (30.11.2022)
Get full text
Journal Article
Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production
Rebourcet, Diane, Mackay, Rosa, Darbey, Annalucia, Curley, Michael K., Jørgensen, Anne, Frederiksen, Hanne, Mitchell, Rod T., O’Shaughnessy, Peter J., Nef, Serge, Smith, Lee B.
Published in The FASEB journal (01.08.2020)
Published in The FASEB journal (01.08.2020)
Get full text
Journal Article
Low-dose tamoxifen treatment in juvenile males has long-term adverse effects on the reproductive system: implications for inducible transgenics
Patel, Saloni H., O’Hara, Laura, Atanassova, Nina, Smith, Sarah E., Curley, Michael K., Rebourcet, Diane, Darbey, Annalucia L., Gannon, Anne-Louise, Sharpe, Richard M., Smith, Lee B.
Published in Scientific reports (21.08.2017)
Published in Scientific reports (21.08.2017)
Get full text
Journal Article
Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid
O'Donnell, Liza, Dagley, Laura F, Curley, Michael, Darbey, Annalucia, O'Shaughnessy, Peter J, Diemer, Thorsten, Pilatz, Adrian, Fietz, Daniela, Stanton, Peter G, Smith, Lee B, Rebourcet, Diane
Published in PloS one (01.09.2023)
Published in PloS one (01.09.2023)
Get full text
Journal Article
Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells
Sararols, Pauline, Stévant, Isabelle, Neirijnck, Yasmine, Rebourcet, Diane, Darbey, Annalucia, Curley, Michael K., Kühne, Françoise, Dermitzakis, Emmanouil, Smith, Lee B., Nef, Serge
Published in Frontiers in cell and developmental biology (28.06.2021)
Published in Frontiers in cell and developmental biology (28.06.2021)
Get full text
Journal Article
Compensatory mechanisms that maintain androgen production in mice lacking key androgen biosynthetic enzymes
Lawrence, Ben M., O'Donnell, Liza, Gannon, Anne‐Louise, Smith, Sarah, Curley, Michael K., Darbey, Annalucia, Mackay, Rosa, O'Shaughnessy, Peter J., Smith, Lee B., Rebourcet, Diane
Published in The FASEB journal (30.11.2024)
Published in The FASEB journal (30.11.2024)
Get full text
Journal Article
Leukemia inhibitory factor-receptor signalling negatively regulates gonadotrophin-stimulated testosterone production in mouse Leydig Cells
Curley, Michael, Darbey, Annalucia, O'Donnell, Liza, Kilcoyne, Karen R., Wilson, Kirsten, Mungall, Will, Rebourcet, Diane, Guo, Jingtao, Mitchell, Rod T., Smith, Lee B.
Published in Molecular and cellular endocrinology (15.03.2022)
Published in Molecular and cellular endocrinology (15.03.2022)
Get full text
Journal Article
Creation of de novo cryptic splicing for ALS and FTD precision medicine
Wilkins, Oscar G, Chien, Max Z Y J, Wlaschin, Josette J, Barattucci, Simone, Harley, Peter, Mattedi, Francesca, Mehta, Puja R, Pisliakova, Maria, Ryadnov, Eugeni, Keuss, Matthew J, Thompson, David, Digby, Holly, Knez, Lea, Simkin, Rebecca L, Diaz, Juan Antinao, Zanovello, Matteo, Brown, Anna-Leigh, Darbey, Annalucia, Karda, Rajvinder, Fisher, Elizabeth M C, Cunningham, Thomas J, Le Pichon, Claire E, Ule, Jernej, Fratta, Pietro
Published in Science (American Association for the Advancement of Science) (04.10.2024)
Published in Science (American Association for the Advancement of Science) (04.10.2024)
Get full text
Journal Article
Leukemia Inhibitory Factor-Receptor is Dispensable for Prenatal Testis Development but is Required in Sertoli cells for Normal Spermatogenesis in Mice
Curley, Michael, Milne, Laura, Smith, Sarah, Atanassova, Nina, Rebourcet, Diane, Darbey, Annalucia, Hadoke, Patrick W. F., Wells, Sara, Smith, Lee B.
Published in Scientific reports (01.08.2018)
Published in Scientific reports (01.08.2018)
Get full text
Journal Article
A comparison of in vivo viral targeting systems identifies adeno‐associated virus serotype 9 (AAV9) as an effective vector for genetic manipulation of Leydig cells in adult mice
Darbey, Annalucia, Rebourcet, Diane, Curley, Michael, Kilcoyne, Karen, Jeffery, Nathan, Reed, Natalie, Milne, Laura, Roesl, Cornelia, Brown, Pamela, Smith, Lee B.
Published in Andrology (Oxford) (01.01.2021)
Published in Andrology (Oxford) (01.01.2021)
Get full text
Journal Article
Acute reduction of Sertoli cell numbers during development leads to a subsequent reduction in sperm numbers in adulthood
Darbey, Annalucia L, O'Shaughnessy, Peter, Pitetti, Jean-Luc, Nef, Serge, Smith, Lee, Rebourcet, Diane
Published in Reproduction Abstracts (23.09.2014)
Published in Reproduction Abstracts (23.09.2014)
Get full text
Journal Article
Creation of de novo cryptic splicing for ALS/FTD precision medicine
Wilkins, Oscar G, Chien, Max Z Y J, Wlaschin, Josette J, Pisliakova, Maria, Thompson, David, Digby, Holly, Simkin, Rebecca L, Diaz, Juan Antinao, Mehta, Puja R, Keuss, Matthew J, Zanovello, Matteo, Brown, Anna-Leigh, Harley, Peter, Darbey, Annalucia, Karda, Rajvinder, Fisher, Elizabeth M C, Cunningham, Tom J, Le Pichon, Claire E, Ule, Jernej, Fratta, Pietro
Published in bioRxiv (15.11.2023)
Published in bioRxiv (15.11.2023)
Get full text
Journal Article
Specific transcriptomic signatures and dual regulation of steroidogenesis between fetal and adult mouse Leydig cells
Sararols, Pauline, Stévant, Isabelle, Neirijnck, Yasmine, Rebourcet, Diane, Darbey, Annalucia, Curley, Michael K, Kuhne, Françoise, Dermitzakis, Emmanouil, Smith, Lee B, Nef, Serge
Published in bioRxiv (14.04.2021)
Published in bioRxiv (14.04.2021)
Get full text
Paper