The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons
Daniels, Brian P., Kofman, Sigal B., Smith, Julian R., Norris, Geoffrey T., Snyder, Annelise G., Kolb, Joseph P., Gao, Xia, Locasale, Jason W., Martinez, Jennifer, Gale, Michael, Loo, Yueh-Ming, Oberst, Andrew
Published in Immunity (Cambridge, Mass.) (15.01.2019)
Published in Immunity (Cambridge, Mass.) (15.01.2019)
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Journal Article
RIPK3 promotes brain region-specific interferon signaling and restriction of tick-borne flavivirus infection
Lindman, Marissa, Angel, Juan P, Estevez, Irving, Chang, Nydia P, Chou, Tsui-Wen, McCourt, Micheal, Atkins, Colm, Daniels, Brian P
Published in PLoS pathogens (01.11.2023)
Published in PLoS pathogens (01.11.2023)
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Journal Article
Developing human pluripotent stem cell-based cerebral organoids with a controllable microglia ratio for modeling brain development and pathology
Xu, Ranjie, Boreland, Andrew J., Li, Xiaoxi, Erickson, Caroline, Jin, Mengmeng, Atkins, Colm, Pang, Zhiping P., Daniels, Brian P., Jiang, Peng
Published in Stem cell reports (10.08.2021)
Published in Stem cell reports (10.08.2021)
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Journal Article
Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity
Snyder, Annelise G, Hubbard, Nicholas W, Messmer, Michelle N, Kofman, Sigal B, Hagan, Cassidy E, Orozco, Susana L, Chiang, Kristy, Daniels, Brian P, Baker, David, Oberst, Andrew
Published in Science immunology (21.06.2019)
Published in Science immunology (21.06.2019)
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Journal Article
MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D
Gutierrez, Kimberley D, Davis, Michael A, Daniels, Brian P, Olsen, Tayla M, Ralli-Jain, Pooja, Tait, Stephen W G, Gale, Jr, Michael, Oberst, Andrew
Published in The Journal of immunology (1950) (01.03.2017)
Published in The Journal of immunology (1950) (01.03.2017)
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Journal Article
2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo
Szretter, Kristy J, Daniels, Brian P, Cho, Hyelim, Gainey, Maria D, Yokoyama, Wayne M, Gale, Jr, Michael, Virgin, Herbert W, Klein, Robyn S, Sen, Ganes C, Diamond, Michael S
Published in PLoS pathogens (2012)
Published in PLoS pathogens (2012)
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Journal Article
RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation
Daniels, Brian P., Snyder, Annelise G., Olsen, Tayla M., Orozco, Susana, Oguin, Thomas H., Tait, Stephen W.G., Martinez, Jennifer, Gale, Michael, Loo, Yueh-Ming, Oberst, Andrew
Published in Cell (06.04.2017)
Published in Cell (06.04.2017)
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Journal Article
RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity
Orozco, Susana L., Daniels, Brian P., Yatim, Nader, Messmer, Michelle N., Quarato, Giovanni, Chen-Harris, Haiyin, Cullen, Sean P., Snyder, Annelise G., Ralli-Jain, Pooja, Frase, Sharon, Tait, Stephen W.G., Green, Douglas R., Albert, Matthew L., Oberst, Andrew
Published in Cell reports (Cambridge) (27.08.2019)
Published in Cell reports (Cambridge) (27.08.2019)
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Journal Article
Copper‐Phosphido Catalysis: Enantioselective Addition of Phosphines to Cyclopropenes
Daniels, Brian S., Hou, Xintong, Corio, Stephanie A., Weissman, Lindsey M., Dong, Vy M., Hirschi, Jennifer S., Nie, Shaozhen
Published in Angewandte Chemie International Edition (04.09.2023)
Published in Angewandte Chemie International Edition (04.09.2023)
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Journal Article
Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier
Lazear, Helen M, Daniels, Brian P, Pinto, Amelia K, Huang, Albert C, Vick, Sarah C, Doyle, Sean E, Gale, Jr, Michael, Klein, Robyn S, Diamond, Michael S
Published in Science translational medicine (22.04.2015)
Published in Science translational medicine (22.04.2015)
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Journal Article
Astrocyte‐T cell crosstalk regulates region‐specific neuroinflammation
Williams, Jessica L., Manivasagam, Sindhu, Smith, Brandon C., Sim, Julia, Vollmer, Lauren L., Daniels, Brian P., Russell, John H., Klein, Robyn S.
Published in Glia (01.07.2020)
Published in Glia (01.07.2020)
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Journal Article
Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection
Daniels, Brian P, Jujjavarapu, Harsha, Durrant, Douglas M, Williams, Jessica L, Green, Richard R, White, James P, Lazear, Helen M, Gale, Jr, Michael, Diamond, Michael S, Klein, Robyn S
Published in The Journal of clinical investigation (01.03.2017)
Published in The Journal of clinical investigation (01.03.2017)
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Journal Article
Fibrillar α-synuclein induces neurotoxic astrocyte activation via RIP kinase signaling and NF-κB
Chou, Tsui-Wen, Chang, Nydia P., Krishnagiri, Medha, Patel, Aisha P., Lindman, Marissa, Angel, Juan P., Kung, Po-Lun, Atkins, Colm, Daniels, Brian P.
Published in Cell death & disease (31.07.2021)
Published in Cell death & disease (31.07.2021)
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Journal Article
The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity
Miner, Jonathan J, Daniels, Brian P, Shrestha, Bimmi, Proenca-Modena, Jose L, Lew, Erin D, Lazear, Helen M, Gorman, Matthew J, Lemke, Greg, Klein, Robyn S, Diamond, Michael S
Published in Nature medicine (01.12.2015)
Published in Nature medicine (01.12.2015)
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Journal Article
Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility
Cruz-Orengo, Lillian, Daniels, Brian P, Dorsey, Denise, Basak, Sarah Alison, Grajales-Reyes, José G, McCandless, Erin E, Piccio, Laura, Schmidt, Robert E, Cross, Anne H, Crosby, Seth D, Klein, Robyn S
Published in The Journal of clinical investigation (01.06.2014)
Published in The Journal of clinical investigation (01.06.2014)
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Journal Article