Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer
Janghorban, Mahnaz, Farrell, Amy S., Allen-Petersen, Brittany L., Pelz, Carl, Daniel, Colin J., Oddo, Jessica, Langer, Ellen M., Christensen, Dale J., Sears, Rosalie C.
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
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Journal Article
Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals
Su, Yulong, Pelz, Carl, Huang, Tao, Torkenczy, Kristof, Wang, Xiaoyan, Cherry, Allison, Daniel, Colin J, Liang, Juan, Nan, Xiaolin, Dai, Mu-Shui, Adey, Andrew, Impey, Soren, Sears, Rosalie C
Published in Genes & development (01.11.2018)
Published in Genes & development (01.11.2018)
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Journal Article
Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis
Farrell, Amy S., Pelz, Carl, Wang, Xiaoyan, Daniel, Colin J., Wang, Zhiping, Su, Yulong, Janghorban, Mahnaz, Zhang, Xiaoli, Morgan, Charlie, Impey, Soren, Sears, Rosalie C.
Published in Molecular and Cellular Biology (01.08.2013)
Published in Molecular and Cellular Biology (01.08.2013)
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Journal Article
Loss of Ambra1 promotes melanoma growth and invasion
Di Leo, Luca, Bodemeyer, Valérie, Bosisio, Francesca M, Claps, Giuseppina, Carretta, Marco, Rizza, Salvatore, Faienza, Fiorella, Frias, Alex, Khan, Shawez, Bordi, Matteo, Pacheco, Maria P, Di Martino, Julie, Bravo-Cordero, Jose J, Daniel, Colin J, Sears, Rosalie C, Donia, Marco, Madsen, Daniel H, Guldberg, Per, Filomeni, Giuseppe, Sauter, Thomas, Robert, Caroline, De Zio, Daniela, Cecconi, Francesco
Published in Nature communications (05.05.2021)
Published in Nature communications (05.05.2021)
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Journal Article
Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer
Farrell, Amy S, Allen-Petersen, Brittany, Daniel, Colin J, Wang, Xiaoyan, Wang, Zhiping, Rodriguez, Sarah, Impey, Soren, Oddo, Jessica, Vitek, Michael P, Lopez, Charles, Christensen, Dale J, Sheppard, Brett, Sears, Rosalie C
Published in Molecular cancer research (01.06.2014)
Published in Molecular cancer research (01.06.2014)
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Journal Article
MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast Cancer
Doha, Zinab O, Wang, Xiaoyan, Calistri, Nicholas L, Eng, Jennifer, Daniel, Colin J, Ternes, Luke, Kim, Eun Na, Pelz, Carl, Munks, Michael, Betts, Courtney, Kwon, Sunjong, Bucher, Elmar, Li, Xi, Waugh, Trent, Tatarova, Zuzana, Blumberg, Dylan, Ko, Aaron, Kirchberger, Nell, Pietenpol, Jennifer A, Sanders, Melinda E, Langer, Ellen M, Dai, Mu-Shui, Mills, Gordon, Chin, Koei, Chang, Young Hwan, Coussens, Lisa M, Gray, Joe W, Heiser, Laura M, Sears, Rosalie C
Published in Nature communications (13.09.2023)
Published in Nature communications (13.09.2023)
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Journal Article
Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression
Zhang, Xiaoli, Farrell, Amy S, Daniel, Colin J, Arnold, Hugh, Scanlan, Charles, Laraway, Bryan J, Janghorban, Mahnaz, Lum, Lawrence, Chen, Dexi, Troxell, Megan, Sears, Rosalie
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
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Journal Article
The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model
Janghorban, Mahnaz, Langer, Ellen M, Wang, Xiaoyan, Zachman, Derek, Daniel, Colin J, Hooper, Jody, Fleming, William H, Agarwal, Anupriya, Sears, Rosalie C
Published in PloS one (2017)
Published in PloS one (2017)
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Journal Article
The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc
Arnold, Hugh K, Zhang, Xiaoli, Daniel, Colin J, Tibbitts, Deanne, Escamilla-Powers, Julie, Farrell, Amy, Tokarz, Sara, Morgan, Charlie, Sears, Rosalie C
Published in The EMBO journal (04.03.2009)
Published in The EMBO journal (04.03.2009)
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Journal Article
Micelle-Formulated Juglone Effectively Targets Pancreatic Cancer and Remodels the Tumor Microenvironment
Shah, Vidhi M, Rizvi, Syed, Smith, Alexander, Tsuda, Motoyuki, Krieger, Madeline, Pelz, Carl, MacPherson, Kevin, Eng, Jenny, Chin, Koei, Munks, Michael W, Daniel, Colin J, Al-Fatease, Adel, Yardimci, Galip Gürkan, Langer, Ellen M, Brody, Jonathan R, Sheppard, Brett C, Alani, Adam Wg, Sears, Rosalie C
Published in Pharmaceutics (21.11.2023)
Published in Pharmaceutics (21.11.2023)
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Journal Article
The Tumor Suppressor Protein HBP1 Is a Novel c-Myc-binding Protein That Negatively Regulates c-Myc Transcriptional Activity
Escamilla-Powers, Julienne R, Daniel, Colin J, Farrell, Amy, Taylor, Karyn, Zhang, Xiaoli, Byers, Sarah, Sears, Rosalie
Published in The Journal of biological chemistry (12.02.2010)
Published in The Journal of biological chemistry (12.02.2010)
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Journal Article
Using local ecological knowledge as evidence to guide management: A community‐led harvest calculator for muskoxen in Greenland
Cuyler, Christine, Daniel, Colin J., Enghoff, Martin, Levermann, Nette, Møller‐Lund, Nuka, Hansen, Per N., Damhus, Ditlev, Danielsen, Finn
Published in Conservation science and practice (01.03.2020)
Published in Conservation science and practice (01.03.2020)
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Journal Article
SUMO protease SENP1 deSUMOylates and stabilizes c-Myc
Sun, Xiao-Xin, Chen, Yingxiao, Su, Yulong, Wang, Xiaoyan, Chauhan, Krishna Mohan, Liang, Juan, Daniel, Colin J., Sears, Rosalie C., Dai, Mu-Shui
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2018)
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Journal Article
Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups
Archer, Tenley C., Ehrenberger, Tobias, Mundt, Filip, Gold, Maxwell P., Krug, Karsten, Mah, Clarence K., Mahoney, Elizabeth L., Daniel, Colin J., LeNail, Alexander, Ramamoorthy, Divya, Mertins, Philipp, Mani, D.R., Zhang, Hailei, Gillette, Michael A., Clauser, Karl, Noble, Michael, Tang, Lauren C., Pierre-François, Jessica, Silterra, Jacob, Jensen, James, Tamayo, Pablo, Korshunov, Andrey, Pfister, Stefan M., Kool, Marcel, Northcott, Paul A., Sears, Rosalie C., Lipton, Jonathan O., Carr, Steven A., Mesirov, Jill P., Pomeroy, Scott L., Fraenkel, Ernest
Published in Cancer cell (10.09.2018)
Published in Cancer cell (10.09.2018)
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Journal Article
Effects of 21st‐century climate, land use, and disturbances on ecosystem carbon balance in California
Sleeter, Benjamin M., Marvin, David C., Cameron, D. Richard, Selmants, Paul C., Westerling, A.LeRoy, Kreitler, Jason, Daniel, Colin J., Liu, Jinxun, Wilson, Tamara S.
Published in Global change biology (01.10.2019)
Published in Global change biology (01.10.2019)
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Journal Article
Deregulating MYC in a model of HER2+ breast cancer mimics human intertumoral heterogeneity
Risom, Tyler, Wang, Xiaoyan, Liang, Juan, Zhang, Xiaoli, Pelz, Carl, Campbell, Lydia G, Eng, Jenny, Chin, Koei, Farrington, Caroline, Narla, Goutham, Langer, Ellen M, Sun, Xiao-Xin, Su, Yulong, Daniel, Colin J, Dai, Mu-Shui, Löhr, Christiane V, Sears, Rosalie C
Published in The Journal of clinical investigation (02.01.2020)
Published in The Journal of clinical investigation (02.01.2020)
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