Superior anti-tumor activity of the MDM2 antagonist idasanutlin and the Bcl-2 inhibitor venetoclax in p53 wild-type acute myeloid leukemia models
Lehmann, Christian, Friess, Thomas, Birzele, Fabian, Kiialainen, Anna, Dangl, Markus
Published in Journal of hematology and oncology (28.06.2016)
Published in Journal of hematology and oncology (28.06.2016)
Get full text
Journal Article
1515 Gene edited iPSC-derived macrophages (iMACs) show increased phagocytosis in pre-clinical tumor models
Haake, Kathrin, Mirenda, Michela, Bernard, Quentin, Hublitz, Philip, Gouxette, Lucie, Briscadieu, Martin, Scheinpflug, Philine, Singh, Garima, Hinkelmann, Alica, Schneider, Tanja, Epstein, Michael, Esquerré, Michael, Holtzinger, Audrey, Sommermeyer, Daniel, Paillasse, Michael, Scheel, Andreas, Dangl, Markus, Braun, Monika, Wagner, Nadja
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
Get full text
Journal Article
An improved block equalization scheme for uncertain channel estimation
Dangl, M.A., Sgraja, C., Lindner, J.
Published in IEEE transactions on wireless communications (01.01.2007)
Published in IEEE transactions on wireless communications (01.01.2007)
Get full text
Journal Article
Comparative analysis of HD2 type histone deacetylases in higher plants
Dangl, Markus, Brosch, Gerald, Haas, Hubertus, Loidl, Peter, Lusser, Alexandra
Published in Planta (01.06.2001)
Published in Planta (01.06.2001)
Get full text
Journal Article
A Novel Synthesis of Highly Substituted Perhydropyrrolizines, Perhydroindolizines, and Pyrrolidines: Inhibition of the Peptidyl-Prolyl cis/trans Isomerase (PPIase) Pin1
Siegrist, Romain, Zürcher, Martina, Baumgartner, Corinne, Seiler, Paul, Diederich, François, Daum, Sebastian, Fischer, Gunter, Klein, Christian, Dangl, Markus, Schwaiger, Manfred
Published in Helvetica chimica acta (01.02.2007)
Published in Helvetica chimica acta (01.02.2007)
Get full text
Journal Article
Antitumour activity of the glycoengineered type II anti-CD20 antibody obinutuzumab (GA101) in combination with the MDM2-selective antagonist idasanutlin (RG7388)
Herting, Frank, Herter, Sylvia, Friess, Thomas, Muth, Gunther, Bacac, Marina, Sulcova, Jitka, Umana, Pablo, Dangl, Markus, Klein, Christian
Published in European journal of haematology (01.11.2016)
Published in European journal of haematology (01.11.2016)
Get full text
Journal Article
Abstract 5505: Synergistic anticancer activity of clinical stage, non-genotoxic apoptosis inducing agents RG7388 (MDM2 antagonist) and ABT-199 (GDC-0199, BCL2 inhibitor) in p53 wild-type AML tumor models
Dangl, Markus, Chien, Yuchen, Lehmann, Christian, Friess, Thomas
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
Abstract 11: Development of innovative off-the-shelf cancer immunotherapies with iPSC-derived CD8-positive T-cells
Tawo, Riga, Mirenda, Michela, Cypris, Olivia, Hublitz, Philip, Wagner, Nadja, Epstein, Michael, Esquerre, Michael, Holtzinger, Audrey, Braun, Monika, Dangl, Markus, Grandy, Rodrigo, Sommermeyer, Daniel
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Combination of the Glycoengineered Type II CD20 Antibody Obinutuzumab (GA101) and the MDM2 Selective Antagonist RG7388 Results in Superior Anti-Tumor Activity
Herting, Frank, Herter, Sylvia, Friess, Thomas, Lehmann, Christian, Bacac, Marina, Dangl, Markus, Klein, Christian
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
Get full text
Journal Article
Abstract 5244: SIRPα knockout iPSC-derived macrophages (iMACs) are resistant to CD47-dependent inhibition of phagocytosis and efficiently kill tumor cells in pre-clinical models
Haake, Kathrin, Mirenda, Michela, Bernard, Quentin, Hublitz, Philip, Gouxette, Lucie, Briscadieu, Martin, Scheinpflug, Philine, Singh, Garima, Hinkelmann, Alica, Schneider, Tanja, Esquerré, Michael, Holtzinger, Audrey, Epstein, Michael, Sommermeyer, Daniel, Paillasse, Michael, Scheel, Andreas, Dangl, Markus, Braun, Monika, Wagner, Nadja
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Characterization of two putative histone deacetylase genes from Aspergillus nidulans
Graessle, Stefan, Dangl, Markus, Haas, Hubertus, Mair, Karin, Trojer, Patrick, Brandtner, Eva-Maria, Walton, Jonathan D., Loidl, Peter, Brosch, Gerald
Published in Biochimica et biophysica acta (21.06.2000)
Published in Biochimica et biophysica acta (21.06.2000)
Get full text
Journal Article
MDM2 antagonist clinical response association with a gene expression signature in acute myeloid leukaemia
Zhong, Hua, Chen, Gong, Jukofsky, Lori, Geho, David, Han, Sung Won, Birzele, Fabian, Bader, Sabine, Himmelein, Lucia, Cai, James, Albertyn, Zayed, Rothe, Mark, Essioux, Laurent, Burtscher, Helmut, Middleton, Steven A., Rueger, Ruediger, Chen, Lin‐Chi, Dangl, Markus, Nichols, Gwen, Pierceall, William E.
Published in British journal of haematology (01.11.2015)
Published in British journal of haematology (01.11.2015)
Get full text
Journal Article
Activation of p53 By Novel MDM2 Antagonist RG7388 Overcomes AML Inherent and Acquired Resistance to Bcl-2 Inhibitor ABT-199 (GDC-0199)
Pan, Rongqing, Kojima, Kensuke, Zheng, Zhuanzhen, Ruvolo, Vivian R, Nichols, Gwen, Leverson, Joel D., Dangl, Markus, Konopleva, Marina, Andreeff, Michael
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
Get full text
Journal Article
Antitumour activity of the glycoengineered type II anti‐ CD 20 antibody obinutuzumab ( GA 101) in combination with the MDM 2‐selective antagonist idasanutlin ( RG 7388)
Herting, Frank, Herter, Sylvia, Friess, Thomas, Muth, Gunther, Bacac, Marina, Sulcova, Jitka, Umana, Pablo, Dangl, Markus, Klein, Christian
Published in European journal of haematology (01.11.2016)
Published in European journal of haematology (01.11.2016)
Get full text
Journal Article
Quantification of hepcidin-25 in human serum by isotope dilution micro-HPLC-tandem mass spectrometry
Kobold, Uwe, Dülffer, Thomas, Dangl, Markus, Escherich, Achim, Kubbies, Manfred, Röddiger, Ralf, Wright, Jo Anne
Published in Clinical chemistry (Baltimore, Md.) (01.09.2008)
Published in Clinical chemistry (Baltimore, Md.) (01.09.2008)
Get full text
Journal Article
Effect of Ang-2-VEGF-A Bispecific Antibody in Renal Cell Carcinoma
Bessho, Hideharu, Wong, Bernice, Huang, Dachuan, Tan, Jing, Ong, Choon Kiat, Iwamura, Masatsugu, Hart, Stefan, Dangl, Markus, Thomas, Markus, Teh, Bin Tean
Published in Cancer investigation (14.09.2015)
Published in Cancer investigation (14.09.2015)
Get full text
Journal Article
Abstract 2749: iPSC-derived natural killer cells as the front-runner program of the EVO cells Oncology platform: From inception to translational validation using patient samples
Esquerré, Michael, Holtzinger, Audrey, Pichery, Mélanie, Pfaender, Stefanie, Yumlu, Saniye, Richter, Mandy, Betous, Delphine, Bombarde, Oriane, Gador, Mylène, Sailer, Nadja, Paillasse, Michael, Ysebaert, Loïc, Despas, Fabien, Austen, Matthias, Scheel, Andreas, Dangl, Markus
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article