MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function
Kolbeck, Roland, PhD, Kozhich, Alexander, PhD, Koike, Masamichi, PhD, Peng, Li, PhD, Andersson, Cecilia K., PhD, Damschroder, Melissa M., BA, Reed, Jennifer L., PhD, Woods, Robert, MS, Dall'Acqua, William W., PhD, Stephens, Geoffrey L., PhD, Erjefalt, Jonas S., PhD, Bjermer, Leif, MD, Humbles, Alison A., PhD, Gossage, David, MD, Wu, Herren, PhD, Kiener, Peter A., PhD, Spitalny, George L., PhD, Mackay, Charles R., PhD, Molfino, Nestor A., MD, Coyle, Anthony J., PhD
Published in Journal of allergy and clinical immunology (01.06.2010)
Published in Journal of allergy and clinical immunology (01.06.2010)
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Journal Article
Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models
Allen, Kevin L, Cann, Jennifer, Zhao, Weiguang, Peterson, Norman, Lazzaro, Michelle, Zhong, Haihong, Wu, Herren, Dall'Acqua, William F, Borrok, M Jack, Damschroder, Melissa M, Tsui, Ping, Li, Qing
Published in PloS one (04.06.2020)
Published in PloS one (04.06.2020)
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Journal Article
Experimentally guided computational antibody affinity maturation with de novo docking, modelling and rational design
Cannon, Daniel A, Shan, Lu, Du, Qun, Shirinian, Lena, Rickert, Keith W, Rosenthal, Kim L, Korade, 3rd, Martin, van Vlerken-Ysla, Lilian E, Buchanan, Andrew, Vaughan, Tristan J, Damschroder, Melissa M, Popovic, Bojana
Published in PLoS computational biology (01.05.2019)
Published in PLoS computational biology (01.05.2019)
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Journal Article
Correction: Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models
Allen, Kevin L, Cann, Jennifer, Zhao, Weiguang, Peterson, Norman, Lazzaro, Michelle, Zhong, Haihong, Wu, Herren, Dall'Acqua, William F, Borrok, M Jack, Damschroder, Melissa M, Tsui, Ping, Li, Qing
Published in PloS one (17.05.2021)
Published in PloS one (17.05.2021)
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Journal Article
Generation and Characterization of an IgG4 Monomeric Fc Platform
Shan, Lu, Colazet, Magali, Rosenthal, Kim L, Yu, Xiang-Qing, Bee, Jared S, Ferguson, Andrew, Damschroder, Melissa M, Wu, Herren, Dall'Acqua, William F, Tsui, Ping, Oganesyan, Vaheh
Published in PloS one (01.08.2016)
Published in PloS one (01.08.2016)
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Journal Article
Structural characterization of a mutated, ADCC-enhanced human Fc fragment
Oganesyan, Vaheh, Damschroder, Melissa M., Leach, William, Wu, Herren, Dall’Acqua, William F.
Published in Molecular immunology (01.04.2008)
Published in Molecular immunology (01.04.2008)
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Journal Article
Bi-epitope SPR surfaces: a solution to develop robust immunoassays
Peng, Li, Damschroder, Melissa M, Wu, Herren, Dall'Acqua, William F
Published in PloS one (05.11.2014)
Published in PloS one (05.11.2014)
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Journal Article
In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance
Shan, Lu, Dyk, Nydia Van, Haskins, Nantaporn, Cook, Kimberly M, Rosenthal, Kim L, Mazor, Ronit, Dragulin-Otto, Sonia, Jiang, Yu, Wu, Herren, Dall'Acqua, William F, Borrok, Martin J, Damschroder, Melissa M, Oganesyan, Vaheh
Published in Communications biology (08.09.2021)
Published in Communications biology (08.09.2021)
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Journal Article
Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools
Shan, Lu, Mody, Neil, Sormani, Pietro, Rosenthal, Kim L., Damschroder, Melissa M., Esfandiary, Reza
Published in Molecular pharmaceutics (03.12.2018)
Published in Molecular pharmaceutics (03.12.2018)
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Journal Article
Molecular basis for antagonistic activity of anifrolumab, an anti-interferon-α receptor 1 antibody
Peng, Li, Oganesyan, Vaheh, Wu, Herren, Dall'Acqua, William F, Damschroder, Melissa M
Published in mAbs (04.03.2015)
Published in mAbs (04.03.2015)
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Journal Article
Mechanisms of Neutralization of a Human Anti-α-toxin Antibody
Oganesyan, Vaheh, Peng, Li, Damschroder, Melissa M., Cheng, Li, Sadowska, Agnieszka, Tkaczyk, Christine, Sellman, Bret R., Wu, Herren, Dall'Acqua, William F.
Published in The Journal of biological chemistry (24.10.2014)
Published in The Journal of biological chemistry (24.10.2014)
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Journal Article
Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action
Geoghegan, James C, Diedrich, Gundo, Lu, Xiaojun, Rosenthal, Kim, Sachsenmeier, Kris F, Wu, Herren, Dall'Acqua, William F, Damschroder, Melissa M
Published in mAbs (02.04.2016)
Published in mAbs (02.04.2016)
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Journal Article
Framework shuffling of antibodies to reduce immunogenicity and manipulate functional and biophysical properties
Damschroder, Melissa M., Widjaja, Lusiana, Gill, Parkash S., Krasnoperov, Valery, Jiang, Weidong, Dall’Acqua, William F., Wu, Herren
Published in Molecular immunology (01.04.2007)
Published in Molecular immunology (01.04.2007)
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Journal Article
Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial
Le Lay, John E, Du, Qun, Mehta, Minal B, Bhagroo, Nicholas, Hummer, B Timothy, Falloon, Judith, Carlson, Glenn, Rosenbaum, Anton I, Jin, ChaoYu, Kimko, Holly, Tsai, Lan-Feng, Novick, Steven, Cook, Bill, Han, David, Han, Chang Yeop, Vaisar, Tomas, Chait, Alan, Karathanasis, Sotirios K, Rhodes, Christopher J, Hirshberg, Boaz, Damschroder, Melissa M, Hsia, Judith, Grimsby, Joseph S
Published in Science translational medicine (21.04.2021)
Published in Science translational medicine (21.04.2021)
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Journal Article
Long-acting antibody ligand mimetics for HER4-selective agonism
Shan, Lu, Cook, Kimberly M, Haskins, Nantaporn, Omar, Bilal, Jiang, Yu, Garcia, Andrew, Koksal, Adem, Oganesyan, Vaheh, Rosenthal, Kim, Wu, Herren, Dall'Acqua, William F, Damschroder, Melissa M
Published in Scientific reports (14.10.2020)
Published in Scientific reports (14.10.2020)
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Journal Article
Molecular basis for the antagonistic activity of an anti-CXCR4 antibody
Peng, Li, Damschroder, Melissa M, Cook, Kimberly E, Wu, Herren, Dall'Acqua, William F
Published in mAbs (01.01.2016)
Published in mAbs (01.01.2016)
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