Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis
Govaere, Olivier, Cockell, Simon, Tiniakos, Dina, Queen, Rachel, Younes, Ramy, Vacca, Michele, Alexander, Leigh, Ravaioli, Federico, Palmer, Jeremy, Petta, Salvatore, Boursier, Jerome, Rosso, Chiara, Johnson, Katherine, Wonders, Kristy, Day, Christopher P, Ekstedt, Mattias, Orešič, Matej, Darlay, Rebecca, Cordell, Heather J, Marra, Fabio, Vidal-Puig, Antonio, Bedossa, Pierre, Schattenberg, Jörn M, Clément, Karine, Allison, Michael, Bugianesi, Elisabetta, Ratziu, Vlad, Daly, Ann K, Anstee, Quentin M
Published in Science translational medicine (02.12.2020)
Published in Science translational medicine (02.12.2020)
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Transcriptomics Identify Thrombospondin‐2 as a Biomarker for NASH and Advanced Liver Fibrosis
Kozumi, Kazuhiro, Kodama, Takahiro, Murai, Hiroki, Sakane, Sadatsugu, Govaere, Olivier, Cockell, Simon, Motooka, Daisuke, Kakita, Naruyasu, Yamada, Yukinori, Kondo, Yasuteru, Tahata, Yuki, Yamada, Ryoko, Hikita, Hayato, Sakamori, Ryotaro, Kamada, Yoshihiro, Daly, Ann K., Anstee, Quentin M., Tatsumi, Tomohide, Morii, Eiichi, Takehara, Tetsuo
Published in Hepatology (Baltimore, Md.) (01.11.2021)
Published in Hepatology (Baltimore, Md.) (01.11.2021)
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A Randomized Trial of Genotype-Guided Dosing of Warfarin
Pirmohamed, Munir, Burnside, Girvan, Eriksson, Niclas, Jorgensen, Andrea L, Toh, Cheng Hock, Nicholson, Toby, Kesteven, Patrick, Christersson, Christina, Wahlström, Bengt, Stafberg, Christina, Zhang, J. Eunice, Leathart, Julian B, Kohnke, Hugo, Maitland-van der Zee, Anke H, Williamson, Paula R, Daly, Ann K, Avery, Peter, Kamali, Farhad, Wadelius, Mia
Published in The New England journal of medicine (12.12.2013)
Published in The New England journal of medicine (12.12.2013)
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Journal Article
Weight Loss Decreases Excess Pancreatic Triacylglycerol Specifically in Type 2 Diabetes
Steven, Sarah, Hollingsworth, Kieren G, Small, Peter K, Woodcock, Sean A, Pucci, Andrea, Aribisala, Benjamin, Al-Mrabeh, Ahmad, Daly, Ann K, Batterham, Rachel L, Taylor, Roy
Published in Diabetes care (01.01.2016)
Published in Diabetes care (01.01.2016)
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Polygenic architecture informs potential vulnerability to drug-induced liver injury
Koido, Masaru, Kawakami, Eri, Fukumura, Junko, Noguchi, Yui, Ohori, Momoko, Nio, Yasunori, Nicoletti, Paola, Aithal, Guruprasad P., Daly, Ann K., Watkins, Paul B., Anayama, Hisashi, Dragan, Yvonne, Shinozawa, Tadahiro, Takebe, Takanori
Published in Nature medicine (01.10.2020)
Published in Nature medicine (01.10.2020)
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Pharmacogenomics in practice: a review and implementation guide
Kabbani, Danya, Akika, Reem, Wahid, Ahmed, Daly, Ann K, Cascorbi, Ingolf, Zgheib, Nathalie Khoueiry
Published in Frontiers in pharmacology (18.05.2023)
Published in Frontiers in pharmacology (18.05.2023)
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A multi-factorial analysis of response to warfarin in a UK prospective cohort
Bourgeois, Stephane, Jorgensen, Andrea, Zhang, Eunice J, Hanson, Anita, Gillman, Matthew S, Bumpstead, Suzannah, Toh, Cheng Hock, Williamson, Paula, Daly, Ann K, Kamali, Farhad, Deloukas, Panos, Pirmohamed, Munir
Published in Genome medicine (06.01.2016)
Published in Genome medicine (06.01.2016)
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Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles
Lucena, M. Isabel, Molokhia, Mariam, Shen, Yufeng, Urban, Thomas J, Aithal, Guruprasad P, Andrade, Raúl J, Day, Christopher P, Ruiz–Cabello, Francisco, Donaldson, Peter T, Stephens, Camilla, Pirmohamed, Munir, Romero–Gomez, Manuel, Navarro, Jose Maria, Fontana, Robert J, Miller, Michael, Groome, Max, Bondon–Guitton, Emmanuelle, Conforti, Anita, Stricker, Bruno H.C, Carvajal, Alfonso, Ibanez, Luisa, Yue, Qun–Ying, Eichelbaum, Michel, Floratos, Aris, Pe'er, Itsik, Daly, Mark J, Goldstein, David B, Dillon, John F, Nelson, Matthew R, Watkins, Paul B, Daly, Ann K
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2011)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2011)
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A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures
Govaere, Olivier, Hasoon, Megan, Alexander, Leigh, Cockell, Simon, Tiniakos, Dina, Ekstedt, Mattias, Schattenberg, Jörn M., Boursier, Jerome, Bugianesi, Elisabetta, Ratziu, Vlad, Daly, Ann K., Anstee, Quentin M.
Published in Nature metabolism (01.04.2023)
Published in Nature metabolism (01.04.2023)
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Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles
Nicoletti, Paola, Aithal, Guruprasad P, Chamberlain, Thomas C, Coulthard, Sally, Alshabeeb, Mohammad, Grove, Jane I, Andrade, Raul J, Bjornsson, Einar, Dillon, John F, Hallberg, Par, Lucena, M Isabel, Maitland-van der Zee, Anke H, Martin, Jennifer H, Molokhia, Mariam, Pirmohamed, Munir, Wadelius, Mia, Shen, Yufeng, Nelson, Matthew R, Daly, Ann K
Published in Clinical pharmacology and therapeutics (01.07.2019)
Published in Clinical pharmacology and therapeutics (01.07.2019)
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Pharmacogenetic‐guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon
Verhoef, Talitha I., Redekop, William K., Daly, Ann K., Schie, Rianne M. F., Boer, Anthonius, Maitland‐van der Zee, Anke‐Hilse
Published in British journal of clinical pharmacology (01.04.2014)
Published in British journal of clinical pharmacology (01.04.2014)
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PharmVar GeneFocus: CYP2C9
Sangkuhl, Katrin, Claudio-Campos, Karla, Cavallari, Larisa H, Agundez, Jose A G, Whirl-Carrillo, Michelle, Duconge, Jorge, Del Tredici, Andria L, Wadelius, Mia, Rodrigues Botton, Mariana, Woodahl, Erica L, Scott, Stuart A, Klein, Teri E, Pratt, Victoria M, Daly, Ann K, Gaedigk, Andrea
Published in Clinical pharmacology and therapeutics (01.09.2021)
Published in Clinical pharmacology and therapeutics (01.09.2021)
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The SOD2 C47T polymorphism influences NAFLD fibrosis severity: Evidence from case-control and intra-familial allele association studies
Al-Serri, Ahmad, Anstee, Quentin M, Valenti, Luca, Nobili, Valerio, Leathart, Julian B.S, Dongiovanni, Paola, Patch, Julia, Fracanzani, Anna, Fargion, Silvia, Day, Christopher P, Daly, Ann K
Published in Journal of hepatology (01.02.2012)
Published in Journal of hepatology (01.02.2012)
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Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury
Donaldson, Peter T, Daly, Ann K, Henderson, Jill, Graham, Julia, Pirmohamed, Munir, Bernal, William, Day, Christopher P, Aithal, Guruprasad P
Published in Journal of hepatology (01.12.2010)
Published in Journal of hepatology (01.12.2010)
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