Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression
Hasselluhn, Marie C, Decker-Farrell, Amanda R, Vlahos, Lukas, Thomas, Dafydd H, Curiel-Garcia, Alvaro, Maurer, H Carlo, Wasko, Urszula N, Tomassoni, Lorenzo, Sastra, Stephen A, Palermo, Carmine F, Dalton, Tanner C, Ma, Alice, Li, Fangda, Tolosa, Ezequiel J, Hibshoosh, Hanina, Fernandez-Zapico, Martin E, Muir, Alexander, Califano, Andrea, Olive, Kenneth P
Published in Cancer discovery (08.02.2024)
Published in Cancer discovery (08.02.2024)
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Journal Article
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer
Wasko, Urszula N, Jiang, Jingjing, Dalton, Tanner C, Curiel-Garcia, Alvaro, Edwards, A Cole, Wang, Yingyun, Lee, Bianca, Orlen, Margo, Tian, Sha, Stalnecker, Clint A, Drizyte-Miller, Kristina, Menard, Marie, Dilly, Julien, Sastra, Stephen A, Palermo, Carmine F, Hasselluhn, Marie C, Decker-Farrell, Amanda R, Chang, Stephanie, Jiang, Lingyan, Wei, Xing, Yang, Yu C, Helland, Ciara, Courtney, Haley, Gindin, Yevgeniy, Muonio, Karl, Zhao, Ruiping, Kemp, Samantha B, Clendenin, Cynthia, Sor, Rina, Vostrejs, William P, Hibshman, Priya S, Amparo, Amber M, Hennessey, Connor, Rees, Matthew G, Ronan, Melissa M, Roth, Jennifer A, Brodbeck, Jens, Tomassoni, Lorenzo, Bakir, Basil, Socci, Nicholas D, Herring, Laura E, Barker, Natalie K, Wang, Junning, Cleary, James M, Wolpin, Brian M, Chabot, John A, Kluger, Michael D, Manji, Gulam A, Tsai, Kenneth Y, Sekulic, Miroslav, Lagana, Stephen M, Califano, Andrea, Quintana, Elsa, Wang, Zhengping, Smith, Jacqueline A M, Holderfield, Matthew, Wildes, David, Lowe, Scott W, Badgley, Michael A, Aguirre, Andrew J, Vonderheide, Robert H, Stanger, Ben Z, Baslan, Timour, Der, Channing J, Singh, Mallika, Olive, Kenneth P
Published in Nature (London) (23.05.2024)
Published in Nature (London) (23.05.2024)
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Journal Article
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer
Wasko, Urszula N, Jiang, Jingjing, Dalton, Tanner C, Curiel-Garcia, Alvaro, Edwards, A Cole, Wang, Yingyun, Lee, Bianca, Orlen, Margo, Tian, Sha, Stalnecker, Clint A, Drizyte-Miller, Kristina, Menard, Marie, Dilly, Julien, Sastra, Stephen A, Palermo, Carmine F, Hasselluhn, Marie C, Decker-Farrell, Amanda R, Chang, Stephanie, Jiang, Lingyan, Wei, Xing, Yang, Yu C, Helland, Ciara, Courtney, Haley, Gindin, Yevgeniy, Muonio, Karl, Zhao, Ruiping, Kemp, Samantha B, Clendenin, Cynthia, Sor, Rina, Vostrejs, William P, Hibshman, Priya S, Amparo, Amber M, Hennessey, Connor, Rees, Matthew G, Ronan, Melissa M, Roth, Jennifer A, Brodbeck, Jens, Tomassoni, Lorenzo, Bakir, Basil, Socci, Nicholas D, Herring, Laura E, Barker, Natalie K, Wang, Junning, Cleary, James M, Wolpin, Brian M, Chabot, John A, Kluger, Michael D, Manji, Gulam A, Tsai, Kenneth Y, Sekulic, Miroslav, Lagana, Stephen M, Califano, Andrea, Quintana, Elsa, Wang, Zhengping, Smith, Jacqueline A M, Holderfield, Matthew, Wildes, David, Lowe, Scott W, Badgley, Michael A, Aguirre, Andrew J, Vonderheide, Robert H, Stanger, Ben Z, Baslan, Timour, Der, Channing J, Singh, Mallika, Olive, Kenneth P
Published in Nature (London) (23.05.2024)
Published in Nature (London) (23.05.2024)
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Journal Article
Abstract 1596: Disrupting local immunosuppression by combined myCAF/myeloid targeting in pancreatic cancer
Hasselluhn, Marie C., Thomas, Dafydd, Vlahos, Lukas, Curiel-Garcia, Alvaro, Decker-Farrell, Amanda R., Dalton, Tanner C., Sastra, Stephen A., Palermo, Carmine F., Califano, Andrea, Olive, Kenneth P.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 3874: Adaptive heterogeneity enables the survival of residual malignant PDAC cells in response to RAS-GTP inhibition
Tomassoni, Lorenzo, Wasko, Urszula N., Garcia, Alvaro C., Dalton, Tanner C., Laise, Pasquale, Sastra, Stephen A., Palermo, Carmine F., Califano, Andrea, Olive, Kenneth P.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract A045: Disrupting local immunosuppression through combination myCAF/myeloid targeting in pancreatic cancer
Hasselluhn, Marie C, Vlahos, Lukas, Thomas, Dafydd, Waterbury, Quin T, Garcia, Alvaro Curiel, Decker-Farrell, Amanda R, Dalton, Tanner C, Sastra, Stephen A, Palermo, Carmine F, Wang, Timothy C, Califano, Andrea, Olive, Kenneth P
Published in Cancer research (Chicago, Ill.) (15.09.2024)
Published in Cancer research (Chicago, Ill.) (15.09.2024)
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Journal Article
Abstract C032: Combination CAF/myeloid targeting in PDAC
Hasselluhn, Marie C., Vlahos, Lukas J., Thomas, Dafydd, Garcia, Alvaro Curiel, Decker, Amanda R., Dalton, Tanner C., Sastra, Stephen A., Palermo, Carmine F., Califano, Andrea, Olive, Kenneth P.
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
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Journal Article
Abstract 934: RNA-based precision medicine predicts sensitivity to selinexor in select pancreatic ductal adenocarcinoma patients
Curiel-Garcia, Alvaro, Tomassoni, Lorenzo, Dalton, Tanner C., Decker-Farrell, Amanda R., Palermo, Carmine F., Ross, Daniel R., Sastra, Stephen A., Wasko, Urszula N., Goncalves, Isabel M., Mundi, Prabhot, Bakir, Basil S., Safyan, Rachael A., Hibshoosh, Hanina, Manji, Gulam A., Califano, Andrea, Olive, Kenneth P.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 1927: Resistance to RAS-GTP inhibition in models of pancreatic ductal adenocarcinoma arises downstream of RAS effectors
Wasko, Urszula N., Jiang, Jingjing, Wang, Yingyun, Tomassoni, Lorenzo, Jiang, Lingyan, Menard, Marie, Curiel-Garcia, Alvaro, Dalton, Tanner C., Orlen, Margo, Edwards, Cole, Stalnecker, Clint, Dilly, Julien, Chang, Stephanie, Sastra, Stephen A., Palermo, Carmine F., Baslan, Timour, Tian, Sha, Holderfield, Matthew, Quintana, Elsa, Wang, Zhengping, Smith, Jacqueline A., Califano, Andrea, Wildes, David, Aguirre, Andrew J., Vonderheide, Robert H., Stanger, Ben Z., Lowe, Scott W., Der, Channing J., Singh, Mallika, Olive, Kenneth P.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression
Hasselluhn, Marie C, Decker-Farrell, Amanda R, Vlahos, Lukas, Thomas, Dafydd H, Curiel-Garcia, Alvaro, Maurer, H Carlo, Wasko, Urszula N, Tomassoni, Lorenzo, Sastra, Stephen A, Palermo, Carmine F, Dalton, Tanner C, Ma, Alice, Li, Fangda, Tolosa, Ezequiel J, Hibshoosh, Hanina, Muir, Alexander, Fernandez-Zapico, Martin E, Califano, Andrea, Olive, Kenneth P
Published in bioRxiv (02.03.2023)
Published in bioRxiv (02.03.2023)
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