Drug delivery systems for RNA therapeutics
Paunovska, Kalina, Loughrey, David, Dahlman, James E.
Published in Nature reviews. Genetics (01.05.2022)
Published in Nature reviews. Genetics (01.05.2022)
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Drug delivery systems for CRISPR-based genome editors
Madigan, Victoria, Zhang, Feng, Dahlman, James E.
Published in Nature reviews. Drug discovery (01.11.2023)
Published in Nature reviews. Drug discovery (01.11.2023)
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Emerging Frontiers in Drug Delivery
Tibbitt, Mark W, Dahlman, James E, Langer, Robert
Published in Journal of the American Chemical Society (27.01.2016)
Published in Journal of the American Chemical Society (27.01.2016)
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CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
Platt, Randall J., Chen, Sidi, Zhou, Yang, Yim, Michael J., Swiech, Lukasz, Kempton, Hannah R., Dahlman, James E., Parnas, Oren, Eisenhaure, Thomas M., Jovanovic, Marko, Graham, Daniel B., Jhunjhunwala, Siddharth, Heidenreich, Matthias, Xavier, Ramnik J., Langer, Robert, Anderson, Daniel G., Hacohen, Nir, Regev, Aviv, Feng, Guoping, Sharp, Phillip A., Zhang, Feng
Published in Cell (09.10.2014)
Published in Cell (09.10.2014)
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Treating Cystic Fibrosis with mRNA and CRISPR
Da Silva Sanchez, Alejandro, Paunovska, Kalina, Cristian, Ana, Dahlman, James E
Published in Human gene therapy (01.09.2020)
Published in Human gene therapy (01.09.2020)
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Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease
Dahlman, James E, Abudayyeh, Omar O, Joung, Julia, Gootenberg, Jonathan S, Zhang, Feng, Konermann, Silvana
Published in Nature biotechnology (01.11.2015)
Published in Nature biotechnology (01.11.2015)
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RNA delivery systems
Bhatia, Sangeeta N, Dahlman, James E
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2024)
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Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure
Sager, Hendrik B, Hulsmans, Maarten, Lavine, Kory J, Moreira, Marina B, Heidt, Timo, Courties, Gabriel, Sun, Yuan, Iwamoto, Yoshiko, Tricot, Benoit, Khan, Omar F, Dahlman, James E, Borodovsky, Anna, Fitzgerald, Kevin, Anderson, Daniel G, Weissleder, Ralph, Libby, Peter, Swirski, Filip K, Nahrendorf, Matthias
Published in Circulation research (16.09.2016)
Published in Circulation research (16.09.2016)
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Mild Innate Immune Activation Overrides Efficient Nanoparticle‐Mediated RNA Delivery
Lokugamage, Melissa P., Gan, Zubao, Zurla, Chiara, Levin, Joel, Islam, Fatima Z., Kalathoor, Sujay, Sato, Manaka, Sago, Cory D., Santangelo, Philip J., Dahlman, James E.
Published in Advanced materials (Weinheim) (01.01.2020)
Published in Advanced materials (Weinheim) (01.01.2020)
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Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics
Dahlman, James E., Kauffman, Kevin J., Xing, Yiping, Shaw, Taylor E., Mir, Faryal F., Dlott, Chloe C., Langer, Robert, Anderson, Daniel G., Wang, Eric T.
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
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Using Large Datasets to Understand Nanotechnology
Paunovska, Kalina, Loughrey, David, Sago, Cory D., Langer, Robert, Dahlman, James E.
Published in Advanced materials (Weinheim) (01.10.2019)
Published in Advanced materials (Weinheim) (01.10.2019)
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Treating metastatic cancer with nanotechnology
Schroeder, Avi, Heller, Daniel A., Winslow, Monte M., Dahlman, James E., Pratt, George W., Langer, Robert, Jacks, Tyler, Anderson, Daniel G.
Published in Nature reviews. Cancer (01.01.2012)
Published in Nature reviews. Cancer (01.01.2012)
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Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo
Ni, Huanzhen, Hatit, Marine Z. C., Zhao, Kun, Loughrey, David, Lokugamage, Melissa P., Peck, Hannah E., Cid, Ada Del, Muralidharan, Abinaya, Kim, YongTae, Santangelo, Philip J., Dahlman, James E.
Published in Nature communications (15.08.2022)
Published in Nature communications (15.08.2022)
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Nanoparticles Containing Oxidized Cholesterol Deliver mRNA to the Liver Microenvironment at Clinically Relevant Doses
Paunovska, Kalina, Da Silva Sanchez, Alejandro J., Sago, Cory D., Gan, Zubao, Lokugamage, Melissa P., Islam, Fatima Z., Kalathoor, Sujay, Krupczak, Brandon R., Dahlman, James E.
Published in Advanced materials (Weinheim) (01.04.2019)
Published in Advanced materials (Weinheim) (01.04.2019)
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High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
Sago, Cory D., Lokugamage, Melissa P., Paunovska, Kalina, Vanover, Daryll A., Monaco, Christopher M., Shah, Nirav N., Castro, Marielena Gamboa, Anderson, Shannon E., Rudoltz, Tobi G., Lando, Gwyneth N., Tiwari, Pooja Mummilal, Kirschman, Jonathan L., Willett, Nick, Jang, Young C., Santangelo, Philip J., Bryksin, Anton V., Dahlman, James E.
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2018)
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A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation
Paunovska, Kalina, Sago, Cory D, Monaco, Christopher M, Hudson, William H, Castro, Marielena Gamboa, Rudoltz, Tobi G, Kalathoor, Sujay, Vanover, Daryll A, Santangelo, Philip J, Ahmed, Rafi, Bryksin, Anton V, Dahlman, James E
Published in Nano letters (14.03.2018)
Published in Nano letters (14.03.2018)
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Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs
Lokugamage, Melissa P., Vanover, Daryll, Beyersdorf, Jared, Hatit, Marine Z. C., Rotolo, Laura, Echeverri, Elisa Schrader, Peck, Hannah E., Ni, Huanzhen, Yoon, Jeong-Kee, Kim, YongTae, Santangelo, Philip J., Dahlman, James E.
Published in Nature biomedical engineering (01.09.2021)
Published in Nature biomedical engineering (01.09.2021)
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