CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
Platt, Randall J., Chen, Sidi, Zhou, Yang, Yim, Michael J., Swiech, Lukasz, Kempton, Hannah R., Dahlman, James E., Parnas, Oren, Eisenhaure, Thomas M., Jovanovic, Marko, Graham, Daniel B., Jhunjhunwala, Siddharth, Heidenreich, Matthias, Xavier, Ramnik J., Langer, Robert, Anderson, Daniel G., Hacohen, Nir, Regev, Aviv, Feng, Guoping, Sharp, Phillip A., Zhang, Feng
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Mild Innate Immune Activation Overrides Efficient Nanoparticle‐Mediated RNA Delivery
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Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure
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Published in Circulation research (16.09.2016)
Published in Circulation research (16.09.2016)
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Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics
Dahlman, James E., Kauffman, Kevin J., Xing, Yiping, Shaw, Taylor E., Mir, Faryal F., Dlott, Chloe C., Langer, Robert, Anderson, Daniel G., Wang, Eric T.
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
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Nanoparticles Containing Oxidized Cholesterol Deliver mRNA to the Liver Microenvironment at Clinically Relevant Doses
Paunovska, Kalina, Da Silva Sanchez, Alejandro J., Sago, Cory D., Gan, Zubao, Lokugamage, Melissa P., Islam, Fatima Z., Kalathoor, Sujay, Krupczak, Brandon R., Dahlman, James E.
Published in Advanced materials (Weinheim) (01.04.2019)
Published in Advanced materials (Weinheim) (01.04.2019)
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High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
Sago, Cory D., Lokugamage, Melissa P., Paunovska, Kalina, Vanover, Daryll A., Monaco, Christopher M., Shah, Nirav N., Castro, Marielena Gamboa, Anderson, Shannon E., Rudoltz, Tobi G., Lando, Gwyneth N., Tiwari, Pooja Mummilal, Kirschman, Jonathan L., Willett, Nick, Jang, Young C., Santangelo, Philip J., Bryksin, Anton V., Dahlman, James E.
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2018)
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Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo
Ni, Huanzhen, Hatit, Marine Z. C., Zhao, Kun, Loughrey, David, Lokugamage, Melissa P., Peck, Hannah E., Cid, Ada Del, Muralidharan, Abinaya, Kim, YongTae, Santangelo, Philip J., Dahlman, James E.
Published in Nature communications (15.08.2022)
Published in Nature communications (15.08.2022)
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A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation
Paunovska, Kalina, Sago, Cory D, Monaco, Christopher M, Hudson, William H, Castro, Marielena Gamboa, Rudoltz, Tobi G, Kalathoor, Sujay, Vanover, Daryll A, Santangelo, Philip J, Ahmed, Rafi, Bryksin, Anton V, Dahlman, James E
Published in Nano letters (14.03.2018)
Published in Nano letters (14.03.2018)
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Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs
Lokugamage, Melissa P, Vanover, Daryll, Beyersdorf, Jared, Hatit, Marine Z C, Rotolo, Laura, Echeverri, Elisa Schrader, Peck, Hannah E, Ni, Huanzhen, Yoon, Jeong-Kee, Kim, YongTae, Santangelo, Philip J, Dahlman, James E
Published in Nature biomedical engineering (01.09.2021)
Published in Nature biomedical engineering (01.09.2021)
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Small RNA combination therapy for lung cancer
Xue, Wen, Dahlman, James E., Tammela, Tuomas, Khan, Omar F., Sood, Sabina, Dave, Apeksha, Cai, Wenxin, Chirino, Leilani M., Yang, Gillian R., Bronson, Roderick, Crowley, Denise G., Sahay, Gaurav, Schroeder, Avi, Langer, Robert, Anderson, Daniel G., Jacks, Tyler
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2014)
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Universal Barcoding Predicts In Vivo ApoE-Independent Lipid Nanoparticle Delivery
Da Silva Sanchez, Alejandro J., Dobrowolski, Curtis, Cristian, Ana, Echeverri, Elisa Schrader, Zhao, Kun, Hatit, Marine Z. C., Loughrey, David, Paunovska, Kalina, Dahlman, James E.
Published in Nano letters (22.06.2022)
Published in Nano letters (22.06.2022)
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Dobrowolski, Curtis, Paunovska, Kalina, Hatit, Marine Z C, Lokugamage, Melissa P, Dahlman, James E
Published in Advanced Healthcare Materials (01.08.2021)
Published in Advanced Healthcare Materials (01.08.2021)
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Hua, Xuanwen, Han, Keyi, Mandracchia, Biagio, Radmand, Afsane, Liu, Wenhao, Kim, Hyejin, Yuan, Zhou, Ehrlich, Samuel M, Li, Kaitao, Zheng, Corey, Son, Jeonghwan, Silva Trenkle, Aaron D, Kwong, Gabriel A, Zhu, Cheng, Dahlman, James E, Jia, Shu
Published in Nature communications (04.03.2024)
Published in Nature communications (04.03.2024)
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Drug delivery systems for RNA therapeutics
Paunovska, Kalina, Loughrey, David, Dahlman, James E
Published in Nature reviews. Genetics (01.05.2022)
Published in Nature reviews. Genetics (01.05.2022)
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Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands
Gan, Zubao, Lokugamage, Melissa P., Hatit, Marine Z. C., Loughrey, David, Paunovska, Kalina, Sato, Manaka, Cristian, Ana, Dahlman, James E.
Published in Bioengineering & translational medicine (01.09.2020)
Published in Bioengineering & translational medicine (01.09.2020)
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Emerging Frontiers in Drug Delivery
Tibbitt, Mark W, Dahlman, James E, Langer, Robert
Published in Journal of the American Chemical Society (27.01.2016)
Published in Journal of the American Chemical Society (27.01.2016)
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Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles
Hatit, Marine Z. C., Lokugamage, Melissa P., Dobrowolski, Curtis N., Paunovska, Kalina, Ni, Huanzhen, Zhao, Kun, Vanover, Daryll, Beyersdorf, Jared, Peck, Hannah E., Loughrey, David, Sato, Manaka, Cristian, Ana, Santangelo, Philip J., Dahlman, James E.
Published in Nature nanotechnology (01.03.2022)
Published in Nature nanotechnology (01.03.2022)
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Drug delivery systems for CRISPR-based genome editors
Madigan, Victoria, Zhang, Feng, Dahlman, James E
Published in Nature reviews. Drug discovery (01.11.2023)
Published in Nature reviews. Drug discovery (01.11.2023)
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