Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale
Paramasivam, Prasath, Franke, Christian, Stöter, Martin, Höijer, Andreas, Bartesaghi, Stefano, Sabirsh, Alan, Lindfors, Lennart, Arteta, Marianna Yanez, Dahlén, Anders, Bak, Annette, Andersson, Shalini, Kalaidzidis, Yannis, Bickle, Marc, Zerial, Marino
Published in The Journal of cell biology (07.02.2022)
Published in The Journal of cell biology (07.02.2022)
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In Vivo Metabolite Profiles of an N -Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
Li, Xue-Qing, Elebring, Marie, Dahlén, Anders, Weidolf, Lars
Published in Drug metabolism and disposition (01.10.2023)
Published in Drug metabolism and disposition (01.10.2023)
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Stealth Fluorescence Labeling for Live Microscopy Imaging of mRNA Delivery
Baladi, Tom, Nilsson, Jesper R, Gallud, Audrey, Celauro, Emanuele, Gasse, Cécile, Levi-Acobas, Fabienne, Sarac, Ivo, Hollenstein, Marcel R, Dahlén, Anders, Esbjörner, Elin K, Wilhelmsson, L. Marcus
Published in Journal of the American Chemical Society (14.04.2021)
Published in Journal of the American Chemical Society (14.04.2021)
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Intracellular Absolute Quantification of Oligonucleotide Therapeutics by NanoSIMS
Becquart, Cécile, Stulz, Rouven, Thomen, Aurélien, Dost, Maryam, Najafinobar, Neda, Dahlén, Anders, Andersson, Shalini, Ewing, Andrew G., Kurczy, Michael E.
Published in Analytical chemistry (Washington) (26.07.2022)
Published in Analytical chemistry (Washington) (26.07.2022)
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Cross-Species Translation of Biophase Half-Life and Potency of GalNAc-Conjugated siRNAs
Boianelli, Alessandro, Aoki, Yasunori, Ivanov, Maxim, Dahlén, Anders, Gennemark, Peter
Published in Nucleic acid therapeutics (01.12.2022)
Published in Nucleic acid therapeutics (01.12.2022)
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Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein
Davies, Nigel, Hovdal, Daniel, Edmunds, Nicholas, Nordberg, Peter, Dahlén, Anders, Dabkowska, Aleksandra, Arteta, Marianna Yanez, Radulescu, Aurel, Kjellman, Tomas, Höijer, Andreas, Seeliger, Frank, Holmedal, Elin, Andihn, Elisabeth, Bergenhem, Nils, Sandinge, Ann-Sofie, Johansson, Camilla, Hultin, Leif, Johansson, Marie, Lindqvist, Johnny, Björsson, Liselotte, Jing, Yujia, Bartesaghi, Stefano, Lindfors, Lennart, Andersson, Shalini
Published in Molecular therapy. Nucleic acids (04.06.2021)
Published in Molecular therapy. Nucleic acids (04.06.2021)
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Distribution and biotransformation of therapeutic antisense oligonucleotides and conjugates
Weidolf, Lars, Björkbom, Anders, Dahlén, Anders, Elebring, Marie, Gennemark, Peter, Hölttä, Mikko, Janzén, David, Li, XueQing, Andersson, Shalini
Published in Drug discovery today (01.10.2021)
Published in Drug discovery today (01.10.2021)
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Interbase FRET in RNA: from A to Z
Füchtbauer, Anders F, Wranne, Moa S, Bood, Mattias, Weis, Erik, Pfeiffer, Pauline, Nilsson, Jesper R, Dahlén, Anders, Grøtli, Morten, Wilhelmsson, L Marcus
Published in Nucleic acids research (04.11.2019)
Published in Nucleic acids research (04.11.2019)
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Tissue pharmacokinetics of antisense oligonucleotides
Bäckström, Erica, Bonetti, Alessandro, Johnsson, Per, Öhlin, Stefan, Dahlén, Anders, Andersson, Patrik, Andersson, Shalini, Gennemark, Peter
Published in Molecular therapy. Nucleic acids (12.03.2024)
Published in Molecular therapy. Nucleic acids (12.03.2024)
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Discovery of AZD6642, an Inhibitor of 5‑Lipoxygenase Activating Protein (FLAP) for the Treatment of Inflammatory Diseases
Lemurell, Malin, Ulander, Johan, Winiwarter, Susanne, Dahlén, Anders, Davidsson, Öjvind, Emtenäs, Hans, Broddefalk, Johan, Swanson, Marianne, Hovdal, Daniel, Plowright, Alleyn T, Pettersen, Anna, Rydén-Landergren, Marie, Barlind, Jonas, Llinas, Antonio, Herslöf, Margareta, Drmota, Tomas, Sigfridsson, Kalle, Moses, Sara, Whatling, Carl
Published in Journal of medicinal chemistry (22.01.2015)
Published in Journal of medicinal chemistry (22.01.2015)
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Metabolic RNA labeling in non-engineered cells following spontaneous uptake of fluorescent nucleoside phosphate analogues
Pfeiffer, Pauline, Nilsson, Jesper R, Gallud, Audrey, Baladi, Tom, Le, Hoang-Ngoan, Bood, Mattias, Lemurell, Malin, Dahlén, Anders, Grøtli, Morten, Esbjörner, Elin K, Wilhelmsson, L Marcus
Published in Nucleic acids research (20.08.2024)
Published in Nucleic acids research (20.08.2024)
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Fluorescent base analogues in gapmers enable stealth labeling of antisense oligonucleotide therapeutics
Nilsson, Jesper R., Baladi, Tom, Gallud, Audrey, Baždarević, Dženita, Lemurell, Malin, Esbjörner, Elin K., Wilhelmsson, L. Marcus, Dahlén, Anders
Published in Scientific reports (31.05.2021)
Published in Scientific reports (31.05.2021)
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Multiphoton characterization and live cell imaging using fluorescent adenine analogue 2CNqA
Nilsson, Jesper R, Benitez-Martin, Carlos, Sansom, Henry G, Pfeiffer, Pauline, Baladi, Tom, Le, Hoang-Ngoan, Dahlén, Anders, Magennis, Steven W, Wilhelmsson, L. Marcus
Published in Physical chemistry chemical physics : PCCP (02.08.2023)
Published in Physical chemistry chemical physics : PCCP (02.08.2023)
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Interbase-FRET binding assay for pre-microRNAs
Bood, Mattias, del Nogal, Anna Wypijewska, Nilsson, Jesper R., Edfeldt, Fredrik, Dahlén, Anders, Lemurell, Malin, Wilhelmsson, L. Marcus, Grøtli, Morten
Published in Scientific reports (30.04.2021)
Published in Scientific reports (30.04.2021)
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Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor
Wypijewska del Nogal, Anna, Füchtbauer, Anders F, Bood, Mattias, Nilsson, Jesper R, Wranne, Moa S, Sarangamath, Sangamesh, Pfeiffer, Pauline, Rajan, Vinoth Sundar, El-Sagheer, Afaf H, Dahlén, Anders, Brown, Tom, Grøtli, Morten, Wilhelmsson, L Marcus
Published in Nucleic acids research (20.08.2020)
Published in Nucleic acids research (20.08.2020)
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