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Lundh, Morten, Bugliani, Marco, Dahlby, Tina, Chou, Danny Hung-Chieh, Wagner, Bridget, Ghiasi, Seyed Mojtaba, De Tata, Vincenzo, Chen, Zhifei, Lund, Marianne Nissan, Davies, Michael J, Marchetti, Piero, Mandrup-Poulsen, Thomas
Published in Journal of endocrinology (01.06.2017)
Published in Journal of endocrinology (01.06.2017)
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Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling
Ghiasi, Seyed Mojtaba, Dahlby, Tina, Hede Andersen, Caroline, Haataja, Leena, Petersen, Sólrun, Omar-Hmeadi, Muhmmad, Yang, Mingyu, Pihl, Celina, Bresson, Sophie Emilie, Khilji, Muhammad Saad, Klindt, Kristian, Cheta, Oana, Perone, Marcelo J, Tyrberg, Björn, Prats, Clara, Barg, Sebastian, Tengholm, Anders, Arvan, Peter, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz
Published in Diabetes (New York, N.Y.) (01.04.2019)
Published in Diabetes (New York, N.Y.) (01.04.2019)
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Proinflammatory Cytokines Perturb Mouse and Human Pancreatic Islet Circadian Rhythmicity and Induce Uncoordinated β-Cell Clock Gene Expression via Nitric Oxide, Lysine Deacetylases, and Immunoproteasomal Activity
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Published in International journal of molecular sciences (23.12.2020)
Published in International journal of molecular sciences (23.12.2020)
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Possible predisposition for colorectal carcinogenesis due to altered gene expressions in normal appearing mucosa from patients with colorectal neoplasia
Petersen, Christian Hunnicke, Mahmood, Badar, Badsted, Christoffer, Dahlby, Tina, Rasmussen, Hanne Borger, Hansen, Mark Berner, Bindslev, Niels
Published in BMC cancer (28.06.2019)
Published in BMC cancer (28.06.2019)
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The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β
Khilji, Muhammad Saad, Verstappen, Danielle, Dahlby, Tina, Burstein Prause, Michala Cecilie, Pihl, Celina, Bresson, Sophie Emilie, Bryde, Tenna Holgersen, Keller Andersen, Phillip Alexander, Klindt, Kristian, Zivkovic, Dusan, Bousquet-Dubouch, Marie-Pierre, Tyrberg, Björn, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz
Published in PloS one (2020)
Published in PloS one (2020)
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Journal Article
Defective Proinsulin Handling Modulates the MHC I Bound Peptidome and Activates the Inflammasome in β-Cells
Khilji, Muhammad Saad, Faridi, Pouya, Pinheiro-Machado, Erika, Hoefner, Carolin, Dahlby, Tina, Aranha, Ritchlynn, Buus, Søren, Nielsen, Morten, Klusek, Justyna, Mandrup-Poulsen, Thomas, Pandey, Kirti, Purcell, Anthony W, Marzec, Michal T
Published in Biomedicines (30.03.2022)
Published in Biomedicines (30.03.2022)
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Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function
Backe, Marie Balslev, Andersson, Jan Legaard, Bacos, Karl, Christensen, Dan Ploug, Hansen, Jakob Bondo, Dorosz, Jerzy Jòzef, Gajhede, Michael, Dahlby, Tina, Bysani, Madhusudhan, Kristensen, Line Hyltoft, Ling, Charlotte, Olsen, Lars, Mandrup-Poulsen, Thomas
Published in Molecular and cellular endocrinology (15.01.2018)
Published in Molecular and cellular endocrinology (15.01.2018)
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Journal Article
Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in β-Cells
Dahlby, Tina, Simon, Christian, Backe, Marie Balslev, Dahllöf, Mattias Salling, Holson, Edward, Wagner, Bridget K, Böni-Schnetzler, Marianne, Marzec, Michal Tomasz, Lundh, Morten, Mandrup-Poulsen, Thomas
Published in International journal of molecular sciences (29.10.2020)
Published in International journal of molecular sciences (29.10.2020)
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Journal Article
The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94 deficient β cells and is overexpressed in type 2 diabetes pancreatic islets
Khilji, Muhammad Saad, Bresson, Sophie Emilie, Verstappen, Danielle, Pihl, Celina, Andersen, Phillip Alexander Keller, Agergaard, Jette Bach, Dahlby, Tina, Holgersen Bryde, Tenna, Klindt, Kristian, Nielsen, Christian Kronborg, Walentinsson, Anna, Zivkovic, Dusan, Bousquet, Marie-Pierre, Tyrberg, Bjørn, Richardson, Sarah J, Morgan, Noel G, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz
Published in American journal of physiology: endocrinology and metabolism (01.06.2020)
Published in American journal of physiology: endocrinology and metabolism (01.06.2020)
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Journal Article
Acute administration of interleukin‐6 does not increase secretion of glucagon‐like peptide‐1 in mice
Christiansen, Charlotte B., Lind, Sara J., Svendsen, Berit, Balk‐Møller, Emilie, Dahlby, Tina, Kuhre, Rune E., Hartmann, Bolette, Mandrup‐Poulsen, Thomas, Deacon, Carolyn F., Wewer Albrechtsen, Nicolai J., Holst, Jens J.
Published in Physiological reports (01.07.2018)
Published in Physiological reports (01.07.2018)
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Journal Article
Defective proinsulin handling modulates the MHC I bound peptidome and activates the inflammasome in β-cells
Muhammad Saad Khilji, Pinheiro-Machado, Erika, Dahlby, Tina, Aranha, Ritchlynn, Buus, Soren, Nielsen, Morten, Klusek, Justyna, Faridi, Pouya, Purcell, Anthony W, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz
Published in bioRxiv (20.12.2021)
Published in bioRxiv (20.12.2021)
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The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, non-toxic concentrations of interleukin 1 β
Muhammad Saad Khilji, Verstappen, Danielle, Dahlby, Tina, Michala Cecilie Burstein Prause, Pihl, Celina, Sophie Emilie Bresson, Tenna Holgersen Bryde, Klindt, Kristian, Zivkovic, Dusan, Marie-Pierre Bousquet-Dubouch, Tyrberg, Björn, Billestrup, Nils, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz
Published in bioRxiv (30.08.2019)
Published in bioRxiv (30.08.2019)
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