Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response
Kuiper, Caroline, Dachs, Gabi U, Currie, Margaret J, Vissers, Margreet C M
Published in Free radical biology & medicine (01.04.2014)
Published in Free radical biology & medicine (01.04.2014)
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Journal Article
Activation of the hypoxia pathway in breast cancer tissue and patient survival are inversely associated with tumor ascorbate levels
Campbell, Elizabeth J, Dachs, Gabi U, Morrin, Helen R, Davey, Valerie C, Robinson, Bridget A, Vissers, Margreet C M
Published in BMC cancer (03.04.2019)
Published in BMC cancer (03.04.2019)
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Journal Article
Effect of post-implant exercise on tumour growth rate, perfusion and hypoxia in mice
Buss, Linda A, Ang, Abel D, Hock, Barry, Robinson, Bridget A, Currie, Margaret J, Dachs, Gabi U
Published in PloS one (18.03.2020)
Published in PloS one (18.03.2020)
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Journal Article
Vitamin C Transporters in Cancer: Current Understanding and Gaps in Knowledge
Wohlrab, Christina, Phillips, Elisabeth, Dachs, Gabi U
Published in Frontiers in oncology (24.04.2017)
Published in Frontiers in oncology (24.04.2017)
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Journal Article
Patients’ and carers’ priorities for cancer research in Aotearoa/New Zealand
de Vries, Millie, Stewart, Tiria, Ireton, Theona, Keelan, Karen, Jordan, Jennifer, Robinson, Bridget A, Dachs, Gabi U
Published in PloS one (22.08.2023)
Published in PloS one (22.08.2023)
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Journal Article
Effect of immune modulation on the skeletal muscle mitochondrial exercise response: An exploratory study in mice with cancer
Buss, Linda A, Hock, Barry, Merry, Troy L, Ang, Abel D, Robinson, Bridget A, Currie, Margaret J, Dachs, Gabi U
Published in PloS one (19.10.2021)
Published in PloS one (19.10.2021)
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Journal Article
Regulation of the 2-oxoglutarate-dependent dioxygenases and implications for cancer
Vissers, Margreet C M, Kuiper, Caroline, Dachs, Gabi U
Published in Biochemical Society transactions (01.08.2014)
Published in Biochemical Society transactions (01.08.2014)
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Journal Article
Limited Association Between Ascorbate Concentrations and Vitamin C Transporters in Renal Cell Carcinoma Cells and Clinical Samples
Wohlrab, Christina, Vissers, Margreet C M, Burgess, Eleanor R, Nonis, Maria, Phillips, Elisabeth, Robinson, Bridget A, Dachs, Gabi U
Published in Cellular physiology and biochemistry (02.10.2021)
Published in Cellular physiology and biochemistry (02.10.2021)
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Journal Article
Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine
Crake, Rebekah L. I., Burgess, Eleanor R., Wiggins, George A. R., Magon, Nicholas J., Das, Andrew B., Vissers, Margreet C. M., Morrin, Helen R., Royds, Janice A., Slatter, Tania L., Robinson, Bridget A., Phillips, Elisabeth, Dachs, Gabi U.
Published in Scientific reports (01.09.2022)
Published in Scientific reports (01.09.2022)
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Web Resource
The Bioreductive Prodrug PR-104A Is Activated under Aerobic Conditions by Human Aldo-Keto Reductase 1C3
GUISE, Christopher P, ABBATTISTA, Maria R, DONATE, Fernando, WILSON, William R, PATTERSON, Adam V, SINGLETON, Rachelle S, HOLFORD, Samuel D, CONNOLLY, Joanna, DACHS, Gabi U, FOX, Stephen B, POLLOCK, Robert, HARVEY, Justin, GUILFORD, Parry
Published in Cancer research (Chicago, Ill.) (15.02.2010)
Published in Cancer research (Chicago, Ill.) (15.02.2010)
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The Role of 2-Oxoglutarate Dependent Dioxygenases in Gliomas and Glioblastomas: A Review of Epigenetic Reprogramming and Hypoxic Response
Crake, Rebekah L I, Burgess, Eleanor R, Royds, Janice A, Phillips, Elisabeth, Vissers, Margreet C M, Dachs, Gabi U
Published in Frontiers in oncology (25.03.2021)
Published in Frontiers in oncology (25.03.2021)
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Journal Article
Bystander or no bystander for gene directed enzyme prodrug therapy
Dachs, Gabi U, Hunt, Michelle A, Syddall, Sophie, Singleton, Dean C, Patterson, Adam V
Published in Molecules (10.11.2009)
Published in Molecules (10.11.2009)
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Journal Article
Book Review
Low Vitamin C Status in Patients with Cancer Is Associated with Patient and Tumor Characteristics
White, Rebecca, Nonis, Maria, Pearson, John F, Burgess, Eleanor, Morrin, Helen R, Pullar, Juliet M, Spencer, Emma, Vissers, Margreet C M, Robinson, Bridget A, Dachs, Gabi U
Published in Nutrients (05.08.2020)
Published in Nutrients (05.08.2020)
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Journal Article
Vitamin C Administration by Intravenous Infusion Increases Tumor Ascorbate Content in Patients With Colon Cancer: A Clinical Intervention Study
Dachs, Gabi U, Gandhi, Jamish, Wohlrab, Christina, Carr, Anitra C, Morrin, Helen R, Pullar, Juliet M, Bayer, Simone B, Eglinton, Tim W, Robinson, Bridget A, Vissers, Margreet C M
Published in Frontiers in oncology (11.01.2021)
Published in Frontiers in oncology (11.01.2021)
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Journal Article
The Association Between Ascorbate and the Hypoxia-Inducible Factors in Human Renal Cell Carcinoma Requires a Functional Von Hippel-Lindau Protein
Wohlrab, Christina, Vissers, Margreet C M, Phillips, Elisabeth, Morrin, Helen, Robinson, Bridget A, Dachs, Gabi U
Published in Frontiers in oncology (30.11.2018)
Published in Frontiers in oncology (30.11.2018)
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Journal Article
Increased Ascorbate Content of Glioblastoma Is Associated With a Suppressed Hypoxic Response and Improved Patient Survival
Burgess, Eleanor R, Crake, Rebekah L I, Phillips, Elisabeth, Morrin, Helen R, Royds, Janice A, Slatter, Tania L, Wiggins, George A R, Vissers, Margreet C M, Robinson, Bridget A, Dachs, Gabi U
Published in Frontiers in oncology (28.03.2022)
Published in Frontiers in oncology (28.03.2022)
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Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: relationships with markers of tumor hypoxia and microvascularity
Currie, Margaret J., PhD, Beardsley, Brooke E., MBChB, Harris, Gavin C., FRCPath, Gunningham, Sarah P., PhD, Dachs, Gabi U., PhD, Dijkstra, Birgit, FRACS, Morrin, Helen R., BSc, Wells, J. Elisabeth, PhD, Robinson, Bridget A., MD
Published in Human pathology (01.03.2013)
Published in Human pathology (01.03.2013)
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Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3
Abbattista, Maria R, Ashoorzadeh, Amir, Guise, Christopher P, Mowday, Alexandra M, Mittra, Rituparna, Silva, Shevan, Hicks, Kevin O, Bull, Matthew R, Jackson-Patel, Victoria, Lin, Xiaojing, Prosser, Gareth A, Lambie, Neil K, Dachs, Gabi U, Ackerley, David F, Smaill, Jeff B, Patterson, Adam V
Published in Pharmaceuticals (Basel, Switzerland) (26.11.2021)
Published in Pharmaceuticals (Basel, Switzerland) (26.11.2021)
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