Investigation of Unprecedented Sites and Proposition of New Ligands for Programmed Cell Death Protein I through Molecular Dynamics with Probes and Virtual Screening
Andrade, Luca, Albuquerque, Aline, Santos-Costa, Andrielly, Vasconcelos, Disraeli, Savino, Wilson, Sartori, Geraldo Rodrigues, Martins Da Silva, João Herminio
Published in Journal of chemical information and modeling (14.03.2022)
Published in Journal of chemical information and modeling (14.03.2022)
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Journal Article
Immunoinformatics-guided design of a multi-valent vaccine against Rotavirus and Norovirus (ChRNV22)
de Oliveira Matos, Amanda, Vilela Rodrigues, Thaís Cristina, Tiwari, Sandeep, dos Santos Dantas, Pedro Henrique, Sartori, Geraldo Rodrigues, de Carvalho Azevedo, Vasco Ariston, Martins Da Silva, João Herminio, de Castro Soares, Siomar, Silva-Sales, Marcelle, Sales-Campos, Helioswilton
Published in Computers in biology and medicine (01.06.2023)
Published in Computers in biology and medicine (01.06.2023)
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Journal Article
The CDR3 region as the major driver of TREM-1 interaction with its ligands, an in silico characterization
de Oliveira Matos, Amanda, dos Santos Dantas, Pedro Henrique, Colmenares, Mike Telemaco Contreras, Sartori, Geraldo Rodrigues, Silva-Sales, Marcelle, Da Silva, João Herminio Martins, Neves, Bruno Junior, Andrade, Carolina Horta, Sales-Campos, Helioswilton
Published in Computational and structural biotechnology journal (01.01.2023)
Published in Computational and structural biotechnology journal (01.01.2023)
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Journal Article
Structural and molecular modeling features of P2X receptors
Alves, Luiz Anastacio, da Silva, João Herminio Martins, Ferreira, Dinarte Neto Moreira, Fidalgo-Neto, Antonio Augusto, Teixeira, Pedro Celso Nogueira, de Souza, Cristina Alves Magalhães, Caffarena, Ernesto Raúl, de Freitas, Mônica Santos
Published in International journal of molecular sciences (14.03.2014)
Published in International journal of molecular sciences (14.03.2014)
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Journal Article
Polymorphisms in alternative oxidase genes from ecotypes of Arabidopsis and rice revealed an environment‐induced linkage to altitude and rainfall
Thiers, Karine Leitão Lima, da Silva, João Hermínio Martins, Vasconcelos, Disraeli Cavalcante Araújo, Aziz, Shahid, Noceda, Carlos, Arnholdt‐Schmitt, Birgit, Costa, José Hélio
Published in Physiologia plantarum (01.01.2023)
Published in Physiologia plantarum (01.01.2023)
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Journal Article
Discovery of New Zika Protease and Polymerase Inhibitors through the Open Science Collaboration Project OpenZika
Mottin, Melina, de Paula Sousa, Bruna Katiele, de Moraes Roso Mesquita, Nathalya Cristina, de Oliveira, Ketllyn Irene Zagato, Noske, Gabriela Dias, Sartori, Geraldo Rodrigues, de Oliveira Albuquerque, Aline, Urbina, Fabio, Puhl, Ana C., Moreira-Filho, José Teófilo, Souza, Guilherme E., Guido, Rafael V. C., Muratov, Eugene, Neves, Bruno Junior, Martins da Silva, João Hermínio, Clark, Alex E., Siqueira-Neto, Jair L., Perryman, Alexander L., Oliva, Glaucius, Ekins, Sean, Andrade, Carolina Horta
Published in Journal of chemical information and modeling (26.12.2022)
Published in Journal of chemical information and modeling (26.12.2022)
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Naturally acquired antibody response to a Plasmodium falciparum chimeric vaccine candidate GMZ2.6c and its components (MSP-3, GLURP, and Pfs48/45) in individuals living in Brazilian malaria-endemic areas
Baptista, Barbara Oliveira, de Souza, Ana Beatriz Lopes, Riccio, Evelyn Kety Pratt, Bianco-Junior, Cesare, Totino, Paulo Renato Rivas, Martins da Silva, João Hermínio, Theisen, Michael, Singh, Susheel Kumar, Amoah, Linda Eva, Ribeiro-Alves, Marcelo, Souza, Rodrigo Medeiros, Lima-Junior, Josué Costa, Daniel-Ribeiro, Cláudio Tadeu, Pratt-Riccio, Lilian Rose
Published in Malaria journal (04.01.2022)
Published in Malaria journal (04.01.2022)
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Journal Article
Optimization of Resveratrol Used as a Scaffold to Design Histone Deacetylase (HDAC-1 and HDAC-2) Inhibitors
Urias, Beatriz Silva, Pavan, Aline Renata, Albuquerque, Gabriela Ribeiro, Prokopczyk, Igor Muccilo, Alves, Tânia Mara Ferreira, de Melo, Thais Regina Ferreira, Sartori, Geraldo Rodrigues, da Silva, João Hermínio Martins, Chin, Chung Man, Santos, Jean Leandro Dos
Published in Pharmaceuticals (Basel, Switzerland) (01.10.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.10.2022)
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Journal Article
Development of New Potential Inhibitors of β1 Integrins through In Silico Methods—Screening and Computational Validation
Vasconcelos, Disraeli, Chaves, Beatriz, Albuquerque, Aline, Andrade, Luca, Henriques, Andrielly, Sartori, Geraldo, Savino, Wilson, Caffarena, Ernesto, Martins-Da-Silva, João Herminio
Published in Life (Basel, Switzerland) (22.06.2022)
Published in Life (Basel, Switzerland) (22.06.2022)
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Journal Article
In silico Identification and Validation of a Linear and Naturally Immunogenic B-Cell Epitope of the Plasmodium vivax Malaria Vaccine Candidate Merozoite Surface Protein-9
Rodrigues-da-Silva, Rodrigo Nunes, Martins da Silva, João Hermínio, Singh, Balwan, Jiang, Jianlin, Meyer, Esmeralda V S, Santos, Fátima, Banic, Dalma Maria, Moreno, Alberto, Galinski, Mary R, Oliveira-Ferreira, Joseli, Lima-Junior, Josué da Costa
Published in PloS one (20.01.2016)
Published in PloS one (20.01.2016)
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Journal Article
Polymorphisms in plastoquinol oxidase (PTOX) from Arabidopsis accessions indicate SNP-induced structural variants associated with altitude and rainfall
Thiers, Karine Leitão Lima, da Silva, João Hermínio Martins, Sartori, Geraldo Rodrigues, dos Santos, Clesivan Pereira, Saraiva, Kátia Daniella da Cruz, Roque, André Luiz Maia, Arnholdt-Schmitt, Birgit, Costa, José Hélio
Published in Journal of bioenergetics and biomembranes (01.04.2019)
Published in Journal of bioenergetics and biomembranes (01.04.2019)
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Plasmodium vivax metacaspase 1 (PvMCA1) catalytic domain is conserved in field isolates from Brazilian Amazon
de Souza, Hugo Amorim dos Santos, Escafa, Victor Fernandes, Blanco, Carolina Moreira, Baptista, Bárbara de Oliveira, de Barros, Jenifer Peixoto, Riccio, Evelyn Ketty Pratt, Rodrigues, Aline Beatriz Mello, Melo, Gisely Cardoso de, Lacerda, Marcus Vinícius Guimarães de, de Souza, Rodrigo Medeiros, Lima-Junior, Josué da Costa, Guimarães, Ana Carolina Ramos, da Mota, Fabio Faria, da Silva, João Hermínio Martins, Daniel-Ribeiro, Cláudio Tadeu, Pratt-Riccio, Lilian Rose, Totino, Paulo Renato Rivas
Published in Memórias do Instituto Oswaldo Cruz (01.01.2021)
Published in Memórias do Instituto Oswaldo Cruz (01.01.2021)
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Differential expression of recently duplicated PTOX genes in Glycine max during plant development and stress conditions
Maia, Rachel Alves, da Cruz Saraiva, Kátia Daniella, Roque, André Luiz Maia, Thiers, Karine Leitão Lima, dos Santos, Clesivan Pereira, da Silva, João Hermínio Martins, Feijó, Daniel Ferreira, Arnholdt-Schmitt, Birgit, Costa, José Hélio
Published in Journal of bioenergetics and biomembranes (01.10.2019)
Published in Journal of bioenergetics and biomembranes (01.10.2019)
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Journal Article
Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites: Naturally Acquired Humoral Immune Response and B-Cell Epitope Mapping in Brazilian Amazon Inhabitants
Rodrigues-da-Silva, Rodrigo Nunes, Soares, Isabela Ferreira, Lopez-Camacho, Cesar, Martins da Silva, João Hermínio, Perce-da-Silva, Daiana de Souza, Têva, Antônio, Ramos Franco, Antônia Maria, Pinheiro, Francimeire Gomes, Chaves, Lana Bitencourt, Pratt-Riccio, Lilian Rose, Reyes-Sandoval, Arturo, Banic, Dalma Maria, Lima-Junior, Josué da Costa
Published in Frontiers in immunology (07.02.2017)
Published in Frontiers in immunology (07.02.2017)
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Journal Article
Plasmodium vivax Cell Traversal Protein for Ookinetes and Sporozoites (PvCelTOS) gene sequence and potential epitopes are highly conserved among isolates from different regions of Brazilian Amazon
Bitencourt Chaves, Lana, Perce-da-Silva, Daiana de Souza, Rodrigues-da-Silva, Rodrigo Nunes, Martins da Silva, João Hermínio, Cassiano, Gustavo Capatti, Machado, Ricardo Luiz Dantas, Pratt-Riccio, Lilian Rose, Banic, Dalma Maria, Lima-Junior, Josué da Costa
Published in PLoS neglected tropical diseases (01.02.2017)
Published in PLoS neglected tropical diseases (01.02.2017)
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Computationally-obtained structural insights into the molecular interactions between Pidilizumab and binding partners DLL1 and PD-1
Albuquerque, Aline de Oliveira, da Silva Junior, Haroldo Cid, Sartori, Geraldo Rodrigues, Martins da Silva, João Hermínio
Published in Journal of biomolecular structure & dynamics (22.09.2022)
Published in Journal of biomolecular structure & dynamics (22.09.2022)
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Journal Article
Antileishmanial drugs activate inflammatory signaling pathways via toll-like receptors (docking approach) from Leishmania amazonensis-infected macrophages
Valentim-Silva, João Rafael, Macedo, Sharon Rose Aragão, de Barros, Neuza Biguinati, dos Santos Ferreira, Amália, da Silva, João Hermínio Martins, de Figueiredo Nicolete, Larissa Deadame, Nicolete, Roberto
Published in International immunopharmacology (01.08.2020)
Published in International immunopharmacology (01.08.2020)
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Journal Article
In silico identification of inhibitors of ribose 5-phosphate isomerase from Trypanosoma cruzi using ligand and structure based approaches
de V. C. Sinatti, Vanessa, R. Baptista, Luiz Phillippe, Alves-Ferreira, Marcelo, Dardenne, Laurent, Hermínio Martins da Silva, João, Guimarães, Ana Carolina
Published in Journal of molecular graphics & modelling (01.10.2017)
Published in Journal of molecular graphics & modelling (01.10.2017)
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Journal Article
In silico mapping of the dynamic interactions and structure-activity relationship of flavonoid compounds against the immune checkpoint programmed-cell death 1 pathway
Sartori, Geraldo Rodrigues, Albuquerque, Aline de Oliveira, Santos-Costa, Andrielly Henriques, Andrade, Luca Milério, Almeida, Diego da Silva, Gaieta, Eduardo Menezes, Sampaio, Jean Vieira, Albuquerque, Vitória Taiana de Melo Lima, Martins Da Silva, João Hermínio
Published in Frontiers in drug discovery (12.12.2022)
Published in Frontiers in drug discovery (12.12.2022)
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