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Published in Nature chemical biology (01.12.2016)
Published in Nature chemical biology (01.12.2016)
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Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates
Duvall, Jeremy R., Thomas, Joshua D., Bukhalid, Raghida A., Catcott, Kalli C., Bentley, Keith W., Collins, Scott D., Eitas, Timothy, Jones, Brian D., Kelleher, Eugene W., Lancaster, Kelly, Protopopova, Marina, Ray, Soumya S., Ter-Ovanesyan, Elena, Xu, Ling, Yang, Liping, Zurita, Jeffrey, Damelin, Marc, Toader, Dorin, Lowinger, Timothy B.
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Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling
Wawer, Mathias J., Li, Kejie, Gustafsdottir, Sigrun M., Ljos, Vebjorn, Bodycombe, Nicole E., Marton, Melissa A., Sokolnicki, Katherine L., Bray, Mark-Anthony, Kemp, Melissa M., Winchester, Ellen, Taylor, Bradley, Grant, George B., Hon, C. Suk-Yee, Duvall, Jeremy R., Wilson, J. Anthony, Bittker, Joshua A., Dančík, Vlado, Narayan, Rajiv, Subramanian, Aravind, Winckler, Wendy, Golub, Todd R., Carpenter, Anne E., Shamji, Alykhan F., Schreiber, Stuart L., Clemons, Paul A.
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
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Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal
Marian, Christine A., Stoszko, Mateusz, Wang, Lili, Leighty, Matthew W., de Crignis, Elisa, Maschinot, Chad A., Gatchalian, Jovylyn, Carter, Benjamin C., Chowdhury, Basudev, Hargreaves, Diana C., Duvall, Jeremy R., Crabtree, Gerald R., Mahmoudi, Tokameh, Dykhuizen, Emily C.
Published in Cell chemical biology (20.12.2018)
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Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties
Over, Björn, McCarren, Patrick, Artursson, Per, Foley, Michael, Giordanetto, Fabrizio, Grönberg, Gunnar, Hilgendorf, Constanze, Lee, Maurice D, Matsson, Pär, Muncipinto, Giovanni, Pellisson, Mélanie, Perry, Matthew W. D, Svensson, Richard, Duvall, Jeremy R, Kihlberg, Jan
Published in Journal of medicinal chemistry (27.03.2014)
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An Aldol-Based Build/Couple/Pair Strategy for the Synthesis of Medium- and Large-Sized Rings: Discovery of Macrocyclic Histone Deacetylase Inhibitors
Marcaurelle, Lisa A, Comer, Eamon, Dandapani, Sivaraman, Duvall, Jeremy R, Gerard, Baudouin, Kesavan, Sarathy, Lee, Maurice D, Liu, Haibo, Lowe, Jason T, Marie, Jean-Charles, Mulrooney, Carol A, Pandya, Bhaumik A, Rowley, Ann, Ryba, Troy D, Suh, Byung-Chul, Wei, Jingqiang, Young, Damian W, Akella, Lakshmi B, Ross, Nathan T, Zhang, Yan-Ling, Fass, Daniel M, Reis, Surya A, Zhao, Wen-Ning, Haggarty, Stephen J, Palmer, Michelle, Foley, Michael A
Published in Journal of the American Chemical Society (01.12.2010)
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Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries
Lowe, Jason T, Lee, Maurice D, Akella, Lakshmi B, Davoine, Emeline, Donckele, Etienne J, Durak, Landon, Duvall, Jeremy R, Gerard, Baudouin, Holson, Edward B, Joliton, Adrien, Kesavan, Sarathy, Lemercier, Berenice C, Liu, Haibo, Marié, Jean-Charles, Mulrooney, Carol A, Muncipinto, Giovanni, Welzel-O’Shea, Morgan, Panko, Laura M, Rowley, Ann, Suh, Byung-Chul, Thomas, Meryl, Wagner, Florence F, Wei, Jingqiang, Foley, Michael A, Marcaurelle, Lisa A
Published in Journal of organic chemistry (07.09.2012)
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Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression
Nagiec, Marek M, Skepner, Adam P, Negri, Joseph, Eichhorn, Michelle, Kuperwasser, Nicolas, Comer, Eamon, Muncipinto, Giovanni, Subramanian, Aravind, Clish, Clary, Musunuru, Kiran, Duvall, Jeremy R, Foley, Michael, Perez, Jose R, Palmer, Michelle A J
Published in PloS one (26.03.2015)
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An Oligomer-Based Approach to Skeletal Diversity in Small-Molecule Synthesis
Spiegel, David A, Schroeder, Frank C, Duvall, Jeremy R, Schreiber, Stuart L
Published in Journal of the American Chemical Society (22.11.2006)
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Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody-Drug Conjugate for the Treatment of Cancer
Toader, Dorin, Fessler, Shawn P, Collins, Scott D, Conlon, Patrick R, Bollu, Reddy, Catcott, Kalli C, Chin, Chen-Ni, Dirksen, Anouk, Du, Bingfan, Duvall, Jeremy R, Higgins, Stacy, Kozytska, Mariya V, Bellovoda, Kamela, Faircloth, Chelsey, Lee, David, Li, Fu, Qin, Liuliang, Routhier, Caitlin, Shaw, Pamela, Stevenson, Cheri A, Wang, Jason, Wongthida, Phonphimon, Ter-Ovanesyan, Elena, Ditty, Elizabeth, Bradley, Stephen P, Xu, Ling, Yin, Mao, Yurkovetskiy, Aleksandr V, Mosher, Rebecca, Damelin, Marc, Lowinger, Timothy B
Published in Molecular cancer therapeutics (01.09.2023)
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Diversity-Oriented Synthesis Probe Targets Plasmodium falciparum Cytochrome b Ubiquinone Reduction Site and Synergizes With Oxidation Site Inhibitors
Lukens, Amanda K., Heidebrecht, Richard W., Mulrooney, Carol, Beaudoin, Jennifer A., Comer, Eamon, Duvall, Jeremy R., Fitzgerald, Mark E., Masi, Daniela, Galinsky, Kevin, Scherer, Christina A., Palmer, Michelle, Munoz, Benito, Foley, Michael, Schreiber, Stuart L., Wiegand, Roger C., Wirth, Dyann F.
Published in The Journal of infectious diseases (01.04.2015)
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Diversity-Oriented Synthesis-Facilitated Medicinal Chemistry: Toward the Development of Novel Antimalarial Agents
Comer, Eamon, Beaudoin, Jennifer A, Kato, Nobutaka, Fitzgerald, Mark E, Heidebrecht, Richard W, Lee, Maurice duPont, Masi, Daniela, Mercier, Marion, Mulrooney, Carol, Muncipinto, Giovanni, Rowley, Ann, Crespo-Llado, Keila, Serrano, Adelfa E, Lukens, Amanda K, Wiegand, Roger C, Wirth, Dyann F, Palmer, Michelle A, Foley, Michael A, Munoz, Benito, Scherer, Christina A, Duvall, Jeremy R, Schreiber, Stuart L
Published in Journal of medicinal chemistry (23.10.2014)
Published in Journal of medicinal chemistry (23.10.2014)
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Hits, leads and drugs against malaria through diversity-oriented synthesis
Dandapani, Sivaraman, Comer, Eamon, Duvall, Jeremy R, Munoz, Benito
Published in Future medicinal chemistry (01.12.2012)
Published in Future medicinal chemistry (01.12.2012)
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Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation
Frumm, Stacey M., Fan, Zi Peng, Ross, Kenneth N., Duvall, Jeremy R., Gupta, Supriya, VerPlank, Lynn, Suh, Byung-Chul, Holson, Edward, Wagner, Florence F., Smith, William B., Paranal, Ronald M., Bassil, Christopher F., Qi, Jun, Roti, Giovanni, Kung, Andrew L., Bradner, James E., Tolliday, Nicola, Stegmaier, Kimberly
Published in Chemistry & biology (23.05.2013)
Published in Chemistry & biology (23.05.2013)
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Novel diversity-oriented synthesis-derived respiratory syncytial virus inhibitors identified via a high throughput replicon-based screen
Duvall, Jeremy R, VerPlank, Lynn, Ludeke, Barbara, McLeod, Sarah M, Lee, 4th, Maurice D, Vishwanathan, Karthick, Mulrooney, Carol A, Le Quement, Sebastian, Yu, Qin, Palmer, Michelle A, Fleming, Paul, Fearns, Rachel, Foley, Michael A, Scherer, Christina A
Published in Antiviral research (01.07.2016)
Published in Antiviral research (01.07.2016)
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Build/Couple/Pair Strategy for the Synthesis of Stereochemically Diverse Macrolactams via Head-to-Tail Cyclization
Fitzgerald, Mark E, Mulrooney, Carol A, Duvall, Jeremy R, Wei, Jingqiang, Suh, Byung-Chul, Akella, Lakshmi B, Vrcic, Anita, Marcaurelle, Lisa A
Published in ACS combinatorial science (13.02.2012)
Published in ACS combinatorial science (13.02.2012)
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Synthesis of a Stereochemically Diverse Library of Medium-Sized Lactams and Sultams via SNAr Cycloetherification
Gerard, Baudouin, Duvall, Jeremy R, Lowe, Jason T, Murillo, Tiffanie, Wei, Jingqiang, Akella, Lakshmi B, Marcaurelle, Lisa A
Published in ACS combinatorial science (11.07.2011)
Published in ACS combinatorial science (11.07.2011)
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Novel tricyclic glycal-based TRIB1 inducers that reprogram LDL metabolism in hepatic cells
Nagiec, Marek M, Duvall, Jeremy R, Skepner, Adam P, Howe, Eleanor A, Bastien, Jessica, Comer, Eamon, Marie, Jean-Charles, Johnston, Stephen E, Negri, Joseph, Eichhorn, Michelle, Vantourout, Julien, Clish, Clary, Musunuru, Kiran, Foley, Michael, Perez, Jose R, Palmer, Michelle A. J
Published in MedChemComm (01.11.2018)
Published in MedChemComm (01.11.2018)
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