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2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

by PIERARD, Francoise, KAY, David, FRAYSSE, Damien, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, KNEGTEL, Ronald, MIDDLETON, Donald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 28.08.2018

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Patent

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

by AHMAD, NADIA, DAVIS, REBECCA, DURRANT, STEVEN, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, KAY, DAVID, DAVIS, CHRIS, PINDER, JOANNE, SHAW, DAVID, JIMENEZ, JUAN-MIGUEL, PANESAR, MANINDER, PIERARD, FRANCOISE, MIDDLETON, DONALD, ODONNELL, MICHAEL, KNEGTEL, RONALD, TWIN, HEATHER, STORCK, PIERRE-HENRI, FRAYSSE, DAMIEN, BOYALL, DEAN
Year of Publication 31.07.2018

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Patent

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO(1,5ALPHA)PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO(1,5ALPHA)PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

by DAVIS Chris, KNEGTEL Ronald, DAVIS Rebecca, JIMENEZ Juan-Miguel, ETXEBARRIA I JARDI Gorka, PIERARD Francoise, AHMAD Nadia, ODONNELL Michael, STUDLEY John, BOYALL Dean, TWIN Heather, MIDDLETON Donald, FRAYSSE Damien, PANESAR Maninder, KAY David, SHAW David, CHARRIER Jean-Damien, DURRANT Steven, PINDER Joanne, STORCK Pierre-Henri
Year of Publication 31.07.2018

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Patent

Pyrazine derivatives useful as inhibitors of ATR kinase

Pyrazine derivatives useful as inhibitors of ATR kinase

by MACCORMICK, SOMHAIRLE, O'DONNELL, MICHAEL, MORTIMORE, MICHAEL, RUTHERFORD, ALISTAIR, KNEGTEL, RONALD, DURRANT, STEVEN, CHARRIER, JEAN-DAMIEN, KAY, DAVID, PINDER, JOANNE, VIRANI, ANISA NIZARALI, REAPER, PHILIP MICHAEL, YOUNG, STEPHEN
Year of Publication 16.06.2016

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Patent

Substituted pyrazin-2-amines as inhibitors of ATR kinase

Substituted pyrazin-2-amines as inhibitors of ATR kinase

by DURRANT STEVEN, MORTIMORE MICHAEL, O'DONNELL MICHAEL, KAY DAVID, CHARRIER JEAN-DAMIEN, YOUNG STEPHEN, REAPER PHILIP MICHAEL, PINDER JOANNE, KNEGTEL RONALD, RUTHERFORD ALISTAIR, VIRANI ANISA NIZARALI, MACCORMICK SOMHAIRLE
Year of Publication 14.06.2016

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Patent

Caspase inhibitor prodrugs

Caspase inhibitor prodrugs

by DURRANT, STEVEN, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN
Year of Publication 29.04.2009

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Patent

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

by Odonnell, Michael, Davis, Chris, Twin, Heather, Charrier, Jean-Damien, Kay, David, Knegtel, Ronald, Fraysse, Damien, Jimenez, Juan-Miguel, Shaw, David, Panesar, Maninder, Studley, John, Storck, Pierre-Henri, Davis, Rebecca, Etxebarria I Jardi, Gorka, Middleton, Donald, Boyall, Dean, Pierard, Francoise, Ahmad, Nadia, Pinder, Joanne, Durrant, Steven
Year of Publication 13.07.2018

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Patent

Compounds useful as inhibitors of ATR kinase

Compounds useful as inhibitors of ATR kinase

by PIERARD, Francoise, KAY, David, FRAYSSE, Damien, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, KNEGTEL, Ronald, MIDDLETON, Donald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 05.07.2018

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Patent

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

by PIERARD, Francoise, KAY, David, FRAYSSE, Damien, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, KNEGTEL, Ronald, MIDDLETON, Donald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 27.06.2018

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Patent

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZIN-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-Y L)PYRAZOLO[1,5ALPHA]PYRIMIDIN-3-CARBOXAMID SOM ATR-KINASE-INHIBITOR

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZIN-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-Y L)PYRAZOLO[1,5ALPHA]PYRIMIDIN-3-CARBOXAMID SOM ATR-KINASE-INHIBITOR

by PIERARD, Francoise, KAY, David, FRAYSSE, Damien, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, KNEGTEL, Ronald, MIDDLETON, Donald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 14.06.2018

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Patent

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

by PIERARD, Francoise, KAY, David, FRAYSSE, Damien, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, KNEGTEL, Ronald, MIDDLETON, Donald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 11.06.2018

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Patent

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

by Knegtel, Ronald Marcellus Alphonsus, Studley, John R, Twin, Heather, Charrier, Jean-Damien, Durrant, Steven John, O'Donnell, Michael Edward, Kay, David, Fraysse, Damien, Jimenez, Juan-Miguel, Shaw, David Matthew, Panesar, Maninder, Pierard, Francoise Yvonne Theodora Marie, Davis, Christopher John, Storck, Pierre-Henri, Davis, Rebecca, Etxebarria I Jardi, Gorka, Middleton, Donald, Boyall, Dean, Ahmad, Nadia, Pinder, Joanne
Year of Publication 07.06.2018

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Patent

Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators

Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators

by PONTILLO JOSEPH, HADIDA RUAH SARA SABINA, WRIGHT MATTHEW A, SCARLATT SCOTT, CARVALHO MEIRELES LUIS MIGUEL, HURLEY DENNIS JAMES, PANDE, JAYESH, L, SOUSA BENJAMIN A, DURRANT STEVEN JOHN, BULLIN ROBERT, TWIN HEATHER CLARE, MI, JACQUES, R, VIRANI ANISA NIZARALI, STEVENS ROBERT EDWARD, THOMSON STEPHEN ANDREW, ZHOU JINGLAN, WEY CHRISTIAN, KUENZLE ANDREAS, GORDIS SUSAN M, AHMAD NAVEED M, NIGTEL ROBERT M, ECHEBARRIA JADI GORKA, MILLER MARK THOMAS, BAIK, ERIC, M, TSADIK EVGENIJ IGOREVICH, NEUBERT, TIMOTHY, D, NORTH KATHARINE, DODD JAMES, STAMOS DIMITRI, SCHMIDT YVONNE, GALLAN BENJAMIN, SHAW, DAVID, M
Year of Publication 02.04.2024

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Patent

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

2-AMINO-6-FLUORO-N-(5-FLUORO-4-(4-(4-(OXETAN-3-YL)PIPERAZINE-1-CARBONYL)PIPERIDIN-1-YL)PYRIDIN-3-YL)PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMIDE AS INHIBITOR OF ATR KINASE

by MICHAEL ODONNELL, STEVEN DURRANT, DAMIEN FRAYSSE, DAVID KAY, MANINDER PANESAR, JOHN STUDLEY, JUAN-MIGUEL JIMENEZ, CHRIS DAVIS, HEATHER TWIN, DEAN BOYALL, JOANNE PINDER, RONALD KNEGTEL, PIERRE-HENRI STORCK, JARDI GORKA ETXEBARRIA I, DONALD MIDDLETON, FRANCOISE PIERARD, JEAN-DAMIEN CHARRIER, REBECCA DAVIS, NADIA AHMAD, DAVID SHAW
Year of Publication 01.06.2018

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Patent

métodos para preparar derivados de pirimidina úteis como inibidores de protéina quinase

métodos para preparar derivados de pirimidina úteis como inibidores de protéina quinase

by STEVEN DURRANT, DAVID KAY, JEAN-DAMIEN CHARRIER
Year of Publication 08.09.2015

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Patent

2-Amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-il)piperazin-1-carbonil)piperidin-1-il)piridin-3-il)pirazolo[1,5alfa]pirimidin-3-carboxamida como inhibidor de ATR quinasa

2-Amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-il)piperazin-1-carbonil)piperidin-1-il)piridin-3-il)pirazolo[1,5alfa]pirimidin-3-carboxamida como inhibidor de ATR quinasa

by PIERARD, Francoise, KAY, David, FRAYSSE, Damien, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, KNEGTEL, Ronald, MIDDLETON, Donald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 25.05.2018

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Patent

Compounds useful as inhibitors of ATR kinase

Compounds useful as inhibitors of ATR kinase

by CHARRIER JEAN-DAMIEN, YOUNG STEPHEN, REAPER PHILIP MICHAEL, PINDER JOANNE, DURRANT STEVEN JOHN, KNEGTEL RONALD MARCELLUS ALPHONSUS
Year of Publication 03.03.2015

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Patent

N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels

N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels

by PULLIN, ROBERT, GALAN, BHAIRAVI, AHMAD, NADIA, HURLEY, DENNIS JAMES, THOMSON, STEPHEN ANDREW, ZHOU, JINGLAN, PONTILLO, JOSEPH, DODD, JAMES, CHUDYK, EWA IWONA, SKERRATT, SARAH, HADIDA RUAH, SARA S, PINDER, JOANNE LOUISE, NORTH, KIRI, STAMOS, DEAN, CARVALHO MEIRELES, LIDIO, O'DONNELL, MICHAEL EDWARD, SCHMIDT, YVONNE, SHAW, DAVID MATTHEW, ETXEBARRIA I JARDI, GORKA, DURRANT, STEVEN JOHN, NEUBERT, TIMOTHY DONALD, VIRANI, ANISA NIZARALI, BECK, ELIZABETH MARY, KNEGTEL, RONALD MARCELLUS, WRAY, CHRISTOPHER
Year of Publication 01.04.2023

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Patent

Synthesis of a Stable Pyridyl Boronate and Its Reaction with Aryl and Heteroaryl Halides

Synthesis of a Stable Pyridyl Boronate and Its Reaction with Aryl and Heteroaryl Halides

by Durrant, Steven J., ., et al
Published in ChemInform (29.05.2007)

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Journal Article

THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES

THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES

by DURRANT STEVEN, KEILY SHAZIA, CHARRIER JEAN-DAMIEN, BRENCHLEY GUY, KNEGTEL RONALD, RAMAYA SHARN
Year of Publication 21.11.2013

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Patent

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