Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer’s disease mouse model
Ng, Roy Chun-Laam, Jian, Min, Ma, Oscar Ka-Fai, Bunting, Myriam, Kwan, Jason Shing-Cheong, Zhou, Guang-Jie, Senthilkumar, Krishnamoorthi, Iyaswamy, Ashok, Chan, Ping-Kei, Li, Min, Leung, Kenneth Mei-Yee, Kumar Durairajan, Siva-Sundara, Lam, Karen Siu-Ling, Chu, Leung-Wing, Festenstein, Richard, Chung, Sookja Kim, Chan, Koon-Ho
Published in Molecular psychiatry (01.10.2021)
Published in Molecular psychiatry (01.10.2021)
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Decrease in the Generation of Amyloid-β Due to Salvianolic Acid B by Modulating BACE1 Activity
Durairajan, Siva Sundara Kumar, Chirasani, Venkat Reddy, Shetty, Sravan Gopalakrishnan, Iyaswamy, Ashok, Malampati, Sandeep, Song, Juxian, Liu, Liangfeng, Huang, Jiandong, Senapati, Sanjib, Li, Min
Published in Current Alzheimer research (01.01.2017)
Published in Current Alzheimer research (01.01.2017)
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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models
Iyaswamy, Ashok, Wang, Xueli, Krishnamoorthi, Senthilkumar, Kaliamoorthy, Venkatapathy, Sreenivasmurthy, Sravan G., Kumar Durairajan, Siva Sundara, Song, Ju-Xian, Tong, Benjamin Chun-kit, Zhu, Zhou, Su, Cheng-Fu, Liu, Jia, Cheung, King-Ho, Lu, Jia-Hong, Tan, Jie-Qiong, Li, Hung Wing, Wong, Man Shing, Li, Min
Published in Redox biology (01.05.2022)
Published in Redox biology (01.05.2022)
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Corynoxine, a Natural Autophagy Enhancer, Promotes the Clearance of Alpha-Synuclein via Akt/mTOR Pathway
Chen, Lei-Lei, Song, Ju-Xian, Lu, Jia-Hong, Yuan, Zhen-Wei, Liu, Liang-Feng, Durairajan, Siva Sundara Kumar, Li, Min
Published in Journal of neuroimmune pharmacology (01.06.2014)
Published in Journal of neuroimmune pharmacology (01.06.2014)
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Journal Article
A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models
Song, Ju‐Xian, Malampati, Sandeep, Zeng, Yu, Durairajan, Siva Sundara Kumar, Yang, Chuan‐Bin, Tong, Benjamin Chun‐Kit, Iyaswamy, Ashok, Shang, Wen‐Bin, Sreenivasmurthy, Sravan Gopalkrishnashetty, Zhu, Zhou, Cheung, King‐Ho, Lu, Jia‐Hong, Tang, Chunzhi, Xu, Nenggui, Li, Min
Published in Aging cell (01.02.2020)
Published in Aging cell (01.02.2020)
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N-2,2,2-Trifluoroethylisatin ketimine as a 1,2-dipolarophile for [3+2]-addition to access optically pure spirothiazolidine oxindoles
Prasad, Madavi S., Bharani, Sankar, Sivaprakash, Murugesan, Vadivelu, Prabha, Kumar, Durairajan Siva Sundara, Chowhan, L. Raju
Published in Organic & biomolecular chemistry (21.06.2023)
Published in Organic & biomolecular chemistry (21.06.2023)
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Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy
Lu, Jia-Hong, Tan, Jie-Qiong, Durairajan, Siva Sundara Kumar, Liu, Liang-Feng, Zhang, Zhuo-Hua, Ma, Long, Shen, Han-Ming, Chan, H.Y. Edwin, Li, Min
Published in Autophagy (01.01.2012)
Published in Autophagy (01.01.2012)
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Gastrointestinal Manifestations of SARS-CoV-2: Transmission, Pathogenesis, Immunomodulation, Microflora Dysbiosis, and Clinical Implications
Durairajan, Siva Sundara Kumar, Singh, Abhay Kumar, Saravanan, Udhaya Bharathy, Namachivayam, Mayurikaa, Radhakrishnan, Moorthi, Huang, Jian-Dong, Dhodapkar, Rahul, Zhang, Hongjie
Published in Viruses (24.05.2023)
Published in Viruses (24.05.2023)
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A modified formulation of Huanglian-Jie-Du-Tang reduces memory impairments and β-amyloid plaques in a triple transgenic mouse model of Alzheimer’s disease
Durairajan, Siva Sundara Kumar, Iyaswamy, Ashok, Shetty, Sravan Gopalakrishna, Kammella, Ananth Kumar, Malampati, Sandeep, Shang, Wenbin, Yang, Chuanbin, Song, Juxian, Chung, Sookja, Huang, Jiandong, Ilango, Kaliappan, Han, Quan-Bin, Li, Min
Published in Scientific reports (24.07.2017)
Published in Scientific reports (24.07.2017)
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A Novel Species of Penicillium With Inhibitory Effects Against Pyricularia oryzae and Fungal Pathogens Inducing Citrus Diseases
Liang, Li-Juan, Jeewon, Rajesh, Dhandevi, Pem, Durairajan, Siva Sundara Kumar, Li, Hongye, Lin, Fu-Cheng, Wang, Hong-Kai
Published in Frontiers in cellular and infection microbiology (10.02.2021)
Published in Frontiers in cellular and infection microbiology (10.02.2021)
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Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models
Selvarasu, Karthikeyan, Singh, Abhay Kumar, Iyaswamy, Ashok, Gopalkrishnashetty Sreenivasmurthy, Sravan, Krishnamoorthi, Senthilkumar, Bera, Amal Kanti, Huang, Jian-Dong, Durairajan, Siva Sundara Kumar
Published in Frontiers in molecular biosciences (25.10.2022)
Published in Frontiers in molecular biosciences (25.10.2022)
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NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models
Iyaswamy, Ashok, Krishnamoorthi, Senthil Kumar, Song, Ju-Xian, Yang, Chuan-Bin, Kaliyamoorthy, Venkatapathy, Zhang, Huan, Sreenivasmurthy, Sravan G., Malampati, Sandeep, Wang, Zi-Ying, Zhu, Zhou, Tong, Benjamin Chun-Kit, Cheung, King-Ho, Lu, Jia-Hong, Durairajan, Siva Sundara Kumar, Li, Min
Published in Yàowu shi͡p︡in fenxi (01.01.2020)
Published in Yàowu shi͡p︡in fenxi (01.01.2020)
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Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy
Sreenivasmurthy, Sravan Gopalkrishnashetty, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Reddi, Rambabu N., Kammala, Ananth Kumar, Vasudevan, Karthick, Senapati, Sanjib, Zhu, Zhou, Su, Cheng-Fu, Liu, Jia, Guan, Xin-Jie, Chua, Ka-Kit, Cheung, King-Ho, Chen, Hubiao, Zhang, Hong-Jie, Zhang, Yuan, Song, Ju-Xian, Kumar Durairajan, Siva Sundara, Li, Min
Published in Frontiers in molecular biosciences (26.10.2022)
Published in Frontiers in molecular biosciences (26.10.2022)
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Salvianolic acid B inhibits Aβ fibril formation and disaggregates preformed fibrils and protects against Aβ-induced cytotoxicty
Durairajan, Siva Sundara Kumar, Yuan, Qiuju, Xie, Lixia, Chan, Wing-Sai, Kum, Wan-Fung, Koo, Irene, Liu, Chenli, Song, Youqiang, Huang, Jian-Dong, Klein, William L., Li, Min
Published in Neurochemistry international (01.03.2008)
Published in Neurochemistry international (01.03.2008)
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Interaction of Tau with Kinesin-1: Effect of Kinesin-1 Heavy Chain Elimination on Autophagy-Mediated Mutant Tau Degradation
Selvarasu, Karthikeyan, Singh, Abhay Kumar, Dakshinamoorthy, Avinash, Sreenivasmurthy, Sravan Gopalkrishnashetty, Iyaswamy, Ashok, Radhakrishnan, Moorthi, Patnaik, Supriti, Huang, Jian-Dong, Williams, Leonard L, Senapati, Sanjib, Durairajan, Siva Sundara Kumar
Published in Biomedicines (01.01.2024)
Published in Biomedicines (01.01.2024)
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Journal Article
Neuroprotective effects of Astragaloside IV in 6-hydroxydopamine-treated primary nigral cell culture
Chan, Wing-Sai, Durairajan, Siva Sundara Kumar, Lu, Jia-Hong, Wang, Yan, Xie, Li-Xia, Kum, Wan-Fung, Koo, Irene, Yung, Ken Kin Lam, Li, Min
Published in Neurochemistry international (01.11.2009)
Published in Neurochemistry international (01.11.2009)
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Journal Article
Effects of Huanglian-Jie-Du-Tang and its modified formula on the modulation of amyloid-β precursor protein processing in Alzheimer's disease models
Durairajan, Siva Sundara Kumar, Huang, Ying-Yu, Yuen, Pui-Yee, Chen, Lei-Lei, Kwok, Ka-Yan, Liu, Liang-Feng, Song, Ju-Xian, Han, Quan-Bin, Xue, Lei, Chung, Sookja K, Huang, Jian-Dong, Baum, Larry, Senapati, Sanjib, Li, Min
Published in PloS one (26.03.2014)
Published in PloS one (26.03.2014)
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