Nonpeptide angiotensin II receptor antagonists. XI. Pharmacology of EXP3174: an active metabolite of DuP 753, an orally active antihypertensive agent
P C Wong, W A Price, Jr, A T Chiu, J V Duncia, D J Carini, R R Wexler, A L Johnson, P B Timmermans
Published in The Journal of pharmacology and experimental therapeutics (01.10.1990)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1990)
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Nonpeptide angiotensin II receptor antagonists. VII. Cellular and biochemical pharmacology of DuP 753, an orally active antihypertensive agent
CHIU, A. T, MCCALL, D. E, PRICE, W. A, WONG, P. C, CARINI, D. J, DUNCIA, J. V, WEXLER, R. R, YOO, S. E, JOHNSON, A. L, TIMMERMANS, P. B. M. W. M
Published in The Journal of pharmacology and experimental therapeutics (01.02.1990)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.1990)
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Nonpeptide angiotensin II receptor antagonists. VIII. Characterization of functional antagonism displayed by DuP 753, an orally active antihypertensive agent
WONG, P. C, PRICE, W. A, CHIU, A. T, DUNCIA, J. V, CARINI, D. J, WEXLER, R. R, JOHNSON, A. L, TIMMERMANS, P. B. M. W. M
Published in The Journal of pharmacology and experimental therapeutics (01.02.1990)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.1990)
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Identification of imidazo[1,2-b] pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling
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Published in MedChemComm (01.04.2017)
Published in MedChemComm (01.04.2017)
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Identification of angiotensin II receptor subtypes
Chiu, Andrew T., Herblin, William F., McCall, Dale E., Ardecky, Robert J., Carini, David J., Duncia, John V., Pease, Lori J., Wong, Pancras C., Wexler, Ruth R., Johnson, Alexander L., Timmermans, Pieter B.M.W.M.
Published in Biochemical and biophysical research communications (30.11.1989)
Published in Biochemical and biophysical research communications (30.11.1989)
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Nonpeptide angiotensin II receptor antagonists. IX. Antihypertensive activity in rats of DuP 753, an orally active antihypertensive agent
WONG, P. C, PRICE, W. A, CHIU, A. T, DUNCIA, J. V, CARINI, D. J, WEXLER, R. R, JOHNSON, A. L, TIMMERMANS, P. B. M. W. M
Published in The Journal of pharmacology and experimental therapeutics (01.02.1990)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.1990)
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Hypotensive Action of DuP 753, an Angiotensin II Antagonist, in Spontaneously Hypertensive Rats Nonpeptide Angiotensin II Receptor Antagonists: X
Wong, Pancras C, Price, William A, Chiu, Andrew T, Duncia, John V, Carini, David J, Wexler, Ruth R, Johnson, Alexander L, Timmermans, Pieter B.M.W.M
Published in Hypertension (Dallas, Tex. 1979) (01.05.1990)
Published in Hypertension (Dallas, Tex. 1979) (01.05.1990)
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The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonist
Duncia, J V, Carini, D J, Chiu, A T, Johnson, A L, Price, W A, Wong, P C, Wexler, R R, Timmermans, P B
Published in Medicinal research reviews (01.03.1992)
Published in Medicinal research reviews (01.03.1992)
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In vivo pharmacology of DuP 753
Wong, P C, Price, Jr, W A, Chiu, A T, Duncia, J V, Carini, D J, Wexler, R R, Johnson, A L, Timmermans, P B
Published in American journal of hypertension (01.04.1991)
Published in American journal of hypertension (01.04.1991)
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Nonpeptide angiotensin II receptor antagonists. III. Structure-function studies
A T Chiu, J V Duncia, D E McCall, P C Wong, W A Price, Jr, M J Thoolen, D J Carini, A L Johnson, P B Timmermans
Published in The Journal of pharmacology and experimental therapeutics (01.09.1989)
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Published in The Journal of pharmacology and experimental therapeutics (01.09.1989)
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Discovery of losartan, the first angiotensin II receptor antagonist
Timmermans, P B, Duncia, J V, Carini, D J, Chiu, A T, Wong, P C, Wexler, R R, Smith, R D
Published in Journal of human hypertension (01.11.1995)
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Published in Journal of human hypertension (01.11.1995)
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Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors
Duncia, John V., Santella, Joseph B., Anne Higley, C., VanAtten, Mary K., Weber, Patricia C., Alexander, Richard S., Kettner, Charles A., Pruitt, James R., Liauw, Anne Y., Quan, Mimi L., Knabb, Robert M., Wexler, Ruth R.
Published in Bioorganic & medicinal chemistry letters (07.04.1998)
Published in Bioorganic & medicinal chemistry letters (07.04.1998)
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Wong, Pancras C., Chiu, Andrew T., Duncia, John V., Herblin, William F., Smith, Ronald D., Timmermans, Pieter B.M.W.M.
Published in Trends in Endocrinology & Metabolism (01.08.1992)
Published in Trends in Endocrinology & Metabolism (01.08.1992)
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Chiu, A T, McCall, D E, Nguyen, T T, Carini, D J, Duncia, J V, Herblin, W F, Uyeda, R T, Wong, P C, Wexler, R R, Johnson, A L
Published in European journal of pharmacology (24.10.1989)
Published in European journal of pharmacology (24.10.1989)
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Duncia, John V., Santella, Joseph B., Higley, C.Anne, Pitts, William J., Wityak, John, Frietze, William E., Rankin, F.Wayne, Sun, Jung-Hui, Earl, Richard A., Tabaka, A.Christine, Teleha, Christopher A., Blom, Karl F., Favata, Margaret F., Manos, Elizabeth J., Daulerio, Andrea J., Stradley, Deborah A., Horiuchi, Kurumi, Copeland, Robert A., Scherle, Peggy A., Trzaskos, James M., Magolda, Ronald L., Trainor, George L., Wexler, Ruth R., Hobbs, Frank W., Olson, Richard E.
Published in Bioorganic & medicinal chemistry letters (20.10.1998)
Published in Bioorganic & medicinal chemistry letters (20.10.1998)
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DuP 532: A second generation of nonpeptide angiotensin II receptor antagonists
Chiu, Andrew T., Carini, David J., Duncia, John V., Leung, Kam H., McCall, Dale E., Price, William A., Wong, Pancras C., Smith, Ronald D., Wexler, Ruth R., Timmermans, Pieter B.M.W.M., Chang, Raymond S.L., Lotti, Victor J.
Published in Biochemical and biophysical research communications (31.05.1991)
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De Lucca, George V, Kim, Ui Tae, Vargo, Brian J, Duncia, John V, Santella, Joseph B, Gardner, Daniel S, Zheng, Changsheng, Liauw, Ann, Wang, Zhang, Emmett, George, Wacker, Dean A, Welch, Patricia K, Covington, Maryanne, Stowell, Nicole C, Wadman, Eric A, Das, Anuk M, Davies, Paul, Yeleswaram, Swamy, Graden, Danielle M, Solomon, Kimberly A, Newton, Robert C, Trainor, George L, Decicco, Carl P, Ko, Soo. S
Published in Journal of medicinal chemistry (24.03.2005)
Published in Journal of medicinal chemistry (24.03.2005)
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Rationale for the chemical development of angiotensin II receptor antagonists
Wexler, R R, Carini, D J, Duncia, J V, Johnson, A L, Wells, G J, Chiu, A T, Wong, P C, Timmermans, P B
Published in American journal of hypertension (01.12.1992)
Published in American journal of hypertension (01.12.1992)
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Antihypertensive mechanism of captopril in renal hypertensive rats: studies with a nonpeptide angiotensin II receptor antagonist and an angiotensin II monoclonal antibody
WONG, P. C, PRICE, W. A, REILLY, T. M, DUNCIA, J. V, TIMMERMANS, P. B. M. W. M
Published in The Journal of pharmacology and experimental therapeutics (01.08.1989)
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Published in The Journal of pharmacology and experimental therapeutics (01.08.1989)
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