Breast Fibroblasts Modulate Early Dissemination, Tumorigenesis, and Metastasis through Alteration of Extracellular Matrix Characteristics
Dumont, Nancy, Liu, Bob, DeFilippis, Rosa Anna, Chang, Hang, Rabban, Joseph T, Karnezis, Anthony N, Tjoe, Judy A, Marx, James, Parvin, Bahram, Tlsty, Thea D
Published in Neoplasia (New York, N.Y.) (01.03.2013)
Published in Neoplasia (New York, N.Y.) (01.03.2013)
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Journal Article
Rare somatic cells from human breast tissue exhibit extensive lineage plasticity
Roy, Somdutta, Gascard, Philippe, Dumont, Nancy, Zhao, Jianxin, Pan, Deng, Petrie, Sarah, Margeta, Marta, Tlsty, Thea D.
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2013)
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Journal Article
Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
Sulahian, Rita, Kwon, Jason J., Walsh, Katherine H., Pailler, Emma, Bosse, Timothy L., Thaker, Maneesha, Almanza, Diego, Dempster, Joshua M., Pan, Joshua, Piccioni, Federica, Dumont, Nancy, Gonzalez, Alfredo, Rennhack, Jonathan, Nabet, Behnam, Bachman, John A., Goodale, Amy, Lee, Yenarae, Bagul, Mukta, Liao, Rosy, Navarro, Adrija, Yuan, Tina L., Ng, Raymond W.S., Raghavan, Srivatsan, Gray, Nathanael S., Tsherniak, Aviad, Vazquez, Francisca, Root, David E., Firestone, Ari J., Settleman, Jeff, Hahn, William C., Aguirre, Andrew J.
Published in Cell reports (Cambridge) (01.10.2019)
Published in Cell reports (Cambridge) (01.10.2019)
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Journal Article
Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers
Dumont, Nancy, Wilson, Matthew B, Crawford, Yongping G, Reynolds, Paul A, Sigaroudinia, Mahvash, Tlsty, Thea D
Published in Proceedings of the National Academy of Sciences - PNAS (30.09.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (30.09.2008)
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Journal Article
No paradox, no progress: inverse cancer comorbidity in people with other complex diseases
Tabarés-Seisdedos, Rafael, Prof, Dumont, Nancy, PhD, Baudot, Anaïs, PhD, Valderas, Jose M, MD, Climent, Joan, PhD, Valencia, Alfonso, PhD, Crespo-Facorro, Benedicto, Prof, Vieta, Eduard, Prof, Gómez-Beneyto, Manuel, Prof, Martínez, Salvador, Prof, Rubenstein, John L, Prof
Published in The lancet oncology (01.06.2011)
Published in The lancet oncology (01.06.2011)
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Journal Article
Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302)
Geretti, Elena, Leonard, Shannon Curtis, Dumont, Nancy, Lee, Helen, Zheng, Jinzi, De Souza, Raquel, Gaddy, Daniel F, Espelin, Christopher W, Jaffray, David A, Moyo, Victor, Nielsen, Ulrik B, Wickham, Thomas J, Hendriks, Bart S
Published in Molecular cancer therapeutics (01.09.2015)
Published in Molecular cancer therapeutics (01.09.2015)
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Journal Article
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
Neggers, Jasper E., Paolella, Brenton R., Asfaw, Adhana, Rothberg, Michael V., Skipper, Thomas A., Yang, Annan, Kalekar, Radha L., Krill-Burger, John M., Dharia, Neekesh V., Kugener, Guillaume, Kalfon, Jérémie, Yuan, Chen, Dumont, Nancy, Gonzalez, Alfredo, Abdusamad, Mai, Li, Yvonne Y., Spurr, Liam F., Wu, Westley W., Durbin, Adam D., Wolpin, Brian M., Piccioni, Federica, Root, David E., Boehm, Jesse S., Cherniack, Andrew D., Tsherniak, Aviad, Hong, Andrew L., Hahn, William C., Stegmaier, Kimberly, Golub, Todd R., Vazquez, Francisca, Aguirre, Andrew J.
Published in Cell reports (Cambridge) (15.12.2020)
Published in Cell reports (Cambridge) (15.12.2020)
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Journal Article
Dual Role of Transforming Growth Factor β in Mammary Tumorigenesis and Metastatic Progression
Muraoka-Cook, Rebecca S, Dumont, Nancy, Arteaga, Carlos L
Published in Clinical cancer research (15.01.2005)
Published in Clinical cancer research (15.01.2005)
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Journal Article
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
Neggers, Jasper E., Paolella, Brenton R., Asfaw, Adhana, Rothberg, Michael V., Skipper, Thomas A., Yang, Annan, Kalekar, Radha L., Krill-Burger, John M., Dharia, Neekesh V., Kugener, Guillaume, Kalfon, Jérémie, Yuan, Chen, Dumont, Nancy, Gonzalez, Alfredo, Abdusamad, Mai, Li, Yvonne Y., Spurr, Liam F., Wu, Westley W., Durbin, Adam D., Wolpin, Brian M., Piccioni, Federica, Root, David E., Boehm, Jesse S., Cherniack, Andrew D., Tsherniak, Aviad, Hong, Andrew L., Hahn, William C., Stegmaier, Kimberly, Golub, Todd R., Vazquez, Francisca, Aguirre, Andrew J.
Published in Cell reports (Cambridge) (13.07.2021)
Published in Cell reports (Cambridge) (13.07.2021)
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Journal Article
Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models
Kamoun, Walid S., Kirpotin, Dmitri B., Huang, Zhaohua Richard, Tipparaju, Suresh K., Noble, Charles O., Hayes, Mark E., Luus, Lia, Koshkaryev, Alexander, Kim, Jaeyeon, Olivier, Ken, Kornaga, Tad, Oyama, Shinji, Askoxylakis, Vasileios, Pien, Christine, Kuesters, Geoffrey, Dumont, Nancy, Lugovskoy, Alexey A., Schihl, Sarah A., Wilton, John H., Geddie, Melissa L., Suchy, James, Grabow, Stephanie, Kohli, Neeraj, Reynolds, C. Patrick, Blaydes, Rachel, Zhou, Yu, Sawyer, Andrew J., Marks, James D., Drummond, Daryl C.
Published in Nature biomedical engineering (01.04.2019)
Published in Nature biomedical engineering (01.04.2019)
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Journal Article
P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT‐253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS
Schalm, Stefanie, Chutake, Yogesh, Breitkopf, Susanne, Mayo, Michele, Dumont, Nancy, Chen, Dapeng, Dixit, Vaishali, Karnik, Rahul, Mcdonald, Alice, Filiatrault, Jessica, Proctor, William, Qi, Frank, Hu, Kan‐Nian, Weiss, Matt, Gollerkeri, Ashwin, Sharma, Kirti, D Growney, Joseph, Williams, Juliet
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
Rapamycin Potentiates Transforming Growth Factor β-Induced Growth Arrest in Nontransformed, Oncogene-Transformed, and Human Cancer Cells
Law, Brian K., Chytil, Anna, Dumont, Nancy, Hamilton, Elizabeth G., Waltner-Law, Mary E., Aakre, Mary E., Covington, Cassondra, Moses, Harold L.
Published in Molecular and Cellular Biology (01.12.2002)
Published in Molecular and Cellular Biology (01.12.2002)
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Journal Article
Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling
Corsello, Steven M, Nagari, Rohith T, Spangler, Ryan D, Rossen, Jordan, Kocak, Mustafa, Bryan, Jordan G, Humeidi, Ranad, Peck, David, Wu, Xiaoyun, Tang, Andrew A, Wang, Vickie M, Bender, Samantha A, Lemire, Evan, Narayan, Rajiv, Montgomery, Philip, Ben-David, Uri, Garvie, Colin W, Chen, Yejia, Rees, Matthew G, Lyons, Nicholas J, McFarland, James M, Wong, Bang T, Wang, Li, Dumont, Nancy, O'Hearn, Patrick J, Stefan, Eric, Doench, John G, Harrington, Caitlin N, Greulich, Heidi, Meyerson, Matthew, Vazquez, Francisca, Subramanian, Aravind, Roth, Jennifer A, Bittker, Joshua A, Boehm, Jesse S, Mader, Christopher C, Tsherniak, Aviad, Golub, Todd R
Published in Nature cancer (01.02.2020)
Published in Nature cancer (01.02.2020)
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Journal Article
TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia
Bhowmick, Neil A., Chytil, Anna, Plieth, David, Gorska, Agnieszka E., Dumont, Nancy, Shappell, Scott, Washington, M. Kay, Neilson, Eric G., Moses, Harold L.
Published in Science (American Association for the Advancement of Science) (06.02.2004)
Published in Science (American Association for the Advancement of Science) (06.02.2004)
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Journal Article
CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissues
DeFilippis, Rosa Anna, Chang, Hang, Dumont, Nancy, Rabban, Joseph T, Chen, Yunn-Yi, Fontenay, Gerald V, Berman, Hal K, Gauthier, Mona L, Zhao, Jianxin, Hu, Donglei, Marx, James J, Tjoe, Judy A, Ziv, Elad, Febbraio, Maria, Kerlikowske, Karla, Parvin, Bahram, Tlsty, Thea D
Published in Cancer discovery (01.09.2012)
Published in Cancer discovery (01.09.2012)
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Abstract 2878: CRISPR-Cas9 screens identify the nuclear export factor NXT1 as a novel therapeutic target in MYCN- amplified neuroblastoma
Malone, Clare F., Dharia, Neekesh V., Kugener, Guillaume, Paolella, Brenton, Rothberg, Michael, Abdusamad, Mai, Gonzalez, Alfredo, Dumont, Nancy, Younger, Scott, Root, David, Vazquez, Francisca, Stegmaier, Kimberly
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract P3-09-01: A ubiquitination cascade regulating the integrated stress response and survival in carcinomas
Cervia, Lisa D, Shibue, Tsukasa, Gaeta, Benjamin, Borah, Ashir A, Leung, Lisa, Li, Naomi, Dumont, Nancy, Gonzalez, Alfredo, Bick, Nolan, Kazachkova, Mariya, Dempster, Joshua M, Krill-Burger, John M, Piccioni, Federica, Udeshi, Namrata D, Olive, Meagan E, Carr, Steven A, Root, David E, McFarland, James M, Vazquez, Francisca, Hahn, William C
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Abstract 3400: Adenosine receptor antagonists exhibit potent and selective off-target killing of FOXA1-high cancers
Corsello, Steven M., Spangler, Ryan D., Humeidi, Ranad, Harrington, Caitlin N., Nagari, Rohith T., Singh, Ritu, Wang, Vickie, Kocak, Mustafa, Rossen, Jordan, Madec, Amael, Dumont, Nancy, Golub, Todd R.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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