Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies
Acin‐Perez, Rebeca, Benincá, Cristiane, Fernandez del Rio, Lucia, Shu, Cynthia, Baghdasarian, Siyouneh, Zanette, Vanessa, Gerle, Christoph, Jiko, Chimari, Khairallah, Ramzi, Khan, Shaharyar, Rincon Fernandez Pacheco, David, Shabane, Byourak, Erion, Karel, Masand, Ruchi, Dugar, Sundeep, Ghenoiu, Cristina, Schreiner, George, Stiles, Linsey, Liesa, Marc, Shirihai, Orian S
Published in The EMBO journal (15.05.2023)
Published in The EMBO journal (15.05.2023)
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A Concise and Efficient Synthesis of Substituted Morpholines
Dugar, Sundeep, Sharma, Amit, Kuila, Bilash, Mahajan, Dinesh, Dwivedi, Sandeep, Tripathi, Vinayak
Published in Synthesis (Stuttgart) (23.12.2014)
Published in Synthesis (Stuttgart) (23.12.2014)
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Progressive transforming growth factor β1-induced lung fibrosis is blocked by an orally active alk5 kinase inhibitor
BONNIAUD, Philippe, MARGETTS, Peter J, PROTTER, Andrew A, GAULDIE, Jack, KOLB, Martin, SCHROEDER, Jane Ann, KAPOUN, Ann M, DAMM, Debby, MURPHY, Alison, CHAKRAVARTY, Sarvajit, DUGAR, Sundeep, HIGGINS, Linda
Published in American journal of respiratory and critical care medicine (15.04.2005)
Published in American journal of respiratory and critical care medicine (15.04.2005)
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Journal Article
SPR965, a Dual PI3K/mTOR Inhibitor, as a Targeted Therapy in Ovarian Cancer
Tran, Arthur-Quan, Sullivan, Stephanie A, Chan, Leo Li-Ying, Yin, Yajie, Sun, Wenchuan, Fang, Ziwei, Dugar, Sundeep, Zhou, Chunxiao, Bae-Jump, Victoria
Published in Frontiers in oncology (15.02.2021)
Published in Frontiers in oncology (15.02.2021)
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Journal Article
Inhibition of Growth and Metastasis of Mouse Mammary Carcinoma by Selective Inhibitor of Transforming Growth Factor-β Type I Receptor Kinase In vivo
RONGRONG GE, RAJEEV, Vaishali, SCHREINER, George, BARNARD, Nicola, REISS, Michael, RAY, Partha, LATTIME, Edmund, RITTLING, Susan, MEDICHERLA, Satya, PROTTER, Andy, MURPHY, Alison, CHAKRAVARTY, Jit, DUGAR, Sundeep
Published in Clinical cancer research (15.07.2006)
Published in Clinical cancer research (15.07.2006)
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Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers
Barnett, Christopher F, Moreno-Ulloa, Aldo, Shiva, Sruti, Ramirez-Sanchez, Israel, Taub, Pam R, Su, Yongxuan, Ceballos, Guillermo, Dugar, Sundeep, Schreiner, George, Villarreal, Francisco
Published in Food & function (01.03.2015)
Published in Food & function (01.03.2015)
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Journal Article
Importance of p38 mitogen-activated protein kinase pathway in allergic airway remodelling and bronchial hyperresponsiveness
Nath, Puneeta, Leung, Sum-Yee, Williams, Alison, Noble, Alistair, Chakravarty, Sundeep Dugar Sarvajit, Luedtke, Gregory R., Medicherla, Satyanarayana, Higgins, Linda S., Protter, Andrew, Chung, Kian Fan
Published in European journal of pharmacology (21.08.2006)
Published in European journal of pharmacology (21.08.2006)
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Abstract 15690: Bioactive Fumarate Improves Cardiac Function and Expands Lifespan in Friedreich's Ataxia
Salinas, Lili, Figueroa, Francisco, Montgomery, Claire, Thai, Phung, Chiamvimonvat, Nipavan, Dugar, Sundeep, Sen, Somdutta, Cortopassi, Gino, Dedkova, Elena N
Published in Circulation (New York, N.Y.) (08.11.2022)
Published in Circulation (New York, N.Y.) (08.11.2022)
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Journal Article
Discovery and Development of SPR519 as a Potent, Selective, and Orally Bioavailable Inhibitor of PI3Kα and mTOR Kinases for the Treatment of Solid Tumors
Mahajan, Dinesh, Sen, Somdutta, Kuila, Bilash, Sharma, Amit, Arora, Reena, Sagar, Milind, Mahapatra, Amal Ray, Gawade, Lalita Babasaheb, Dugar, Sundeep
Published in Journal of medicinal chemistry (08.10.2020)
Published in Journal of medicinal chemistry (08.10.2020)
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Journal Article
(−)‐Epicatechin induces mitochondrial biogenesis and markers of muscle regeneration in adults with Becker muscular dystrophy
McDonald, Craig M., Ramirez‐Sanchez, Israel, Oskarsson, Björn, Joyce, Nanette, Aguilar, Candace, Nicorici, Alina, Dayan, Jonathan, Goude, Erica, Abresch, R. Ted, Villarreal, Francisco, Ceballos, Guillermo, Perkins, Guy, Dugar, Sundeep, Schreiner, George, Henricson, Erik K.
Published in Muscle & nerve (01.02.2021)
Published in Muscle & nerve (01.02.2021)
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Journal Article
Bioactive fumarate improves cardiac function and expands lifespan in Friedrech's ataxia
Salinas, Lili, Figueroa, Francisco, Montgomery, Claire B., Thai, Phung N., Chiamvimonvat, Nipavan, Dugar, Sundeep, Sen, Somdutta, Cortopassi, Gino, Dedkova, Elena N.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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A randomized, placebo-controlled, double-blind study on the effects of (-)-epicatechin on the triglyceride/HDLc ratio and cardiometabolic profile of subjects with hypertriglyceridemia: Unique in vitro effects
Gutiérrez-Salmeán, Gabriela, Meaney, Eduardo, Lanaspa, Miguel A, Cicerchi, Christina, Johnson, Richard J, Dugar, Sundeep, Taub, Pam, Ramírez-Sánchez, Israel, Villarreal, Francisco, Schreiner, George, Ceballos, Guillermo
Published in International journal of cardiology (15.11.2016)
Published in International journal of cardiology (15.11.2016)
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Journal Article
Abstract LB196: SPR965, a PI3K/mTORC1/C2 inhibitor for treatment of chordoma
Dugar, Sundeep, Sen, Somdutta, Maffuid, Paul, Freed, Dan, Sommer, Josh, Anderson, Edward, Hickey, Anthony
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Stimulatory effects of (−)-epicatechin and its enantiomer (+)-epicatechin on mouse frontal cortex neurogenesis markers and short-term memory: proof of concept
Navarrete-Yañez, Viridiana, Garate-Carrillo, Alejandra, Ayala, Marcos, Rodriguez-Castañeda, Antonio, Mendoza-Lorenzo, Patricia, Ceballos, Guillermo, Ordoñez-Razo, Rosa, Dugar, Sundeep, Schreiner, George, Villarreal, Francisco, Ramirez-Sanchez, Israel
Published in Food & function (26.04.2021)
Published in Food & function (26.04.2021)
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Journal Article
p38α-Selective Mitogen-Activated Protein Kinase Inhibitor SD-282 Reduces Inflammation in a Subchronic Model of Tobacco Smoke-Induced Airway Inflammation
Medicherla, Satyanarayana, Fitzgerald, Mary F., Spicer, Dianne, Woodman, Paul, Ma, Jing Y., Kapoun, Ann M., Chakravarty, Sarvajit, Dugar, Sundeep, Protter, Andrew A., Higgins, Linda S.
Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
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