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Published in Journal of medicinal chemistry (27.11.2019)
Published in Journal of medicinal chemistry (27.11.2019)
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Published in ACS medicinal chemistry letters (10.03.2016)
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Published in Journal of the American Chemical Society (08.05.1996)
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Mild Condition for the Deoxygenation of α‑Heteroaryl-Substituted Methanol Derivatives
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MK-8719, a Novel and Selective O -GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy
Wang, Xiaohai, Li, Wenping, Marcus, Jacob, Pearson, Michelle, Song, Lixin, Smith, Karen, Terracina, Giuseppe, Lee, Julie, Hong, Kwok-Lam Karen, Lu, Sherry X., Hyde, Lynn, Chen, Shu-Cheng, Kinsley, David, Melchor, Jerry P., Rubins, Daniel J., Meng, Xiangjun, Hostetler, Eric, Sur, Cyrille, Zhang, Lili, Schachter, Joel B., Hess, J. Fred, Selnick, Harold G., Vocadlo, David J., McEachern, Ernest J., Uslaner, Jason M., Duffy, Joseph L., Smith, Sean M.
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Kaarsholm, Niels C, Lin, Songnian, Yan, Lin, Kelly, Theresa, van Heek, Margaret, Mu, James, Wu, Margaret, Dai, Ge, Cui, Yan, Zhu, Yonghua, Carballo-Jane, Ester, Reddy, Vijay, Zafian, Peter, Huo, Pei, Shi, Shuai, Antochshuk, Valentyn, Ogawa, Aimie, Liu, Franklin, Souza, Sandra C, Seghezzi, Wolfgang, Duffy, Joseph L, Erion, Mark, Nargund, Ravi P, Kelley, David E
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Published in Bioorganic & medicinal chemistry letters (01.07.2020)
Published in Bioorganic & medicinal chemistry letters (01.07.2020)
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Clausen, Dane J., Liu, Jian, Yu, Wensheng, Duffy, Joseph L., Chung, Christine C., Myers, Robert W., Klein, Daniel J., Fells, James, Holloway, Kate, Wu, Jin, Wu, Guoxin, Howell, Bonnie J., Barnard, Richard J.O., Kozlowski, Joseph
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Vachal, Petr, Duffy, Joseph L, Campeau, Louis-Charles, Amin, Rupesh P, Mitra, Kaushik, Murphy, Beth Ann, Shao, Pengcheng P, Sinclair, Peter J, Ye, Feng, Katipally, Revathi, Lu, Zhijian, Ondeyka, Debra, Chen, Yi-Heng, Zhao, Kake, Sun, Wanying, Tyagarajan, Sriram, Bao, Jianming, Wang, Sheng-Ping, Cote, Josee, Lipardi, Concetta, Metzger, Daniel, Leung, Dennis, Hartmann, Georgy, Wollenberg, Gordon K, Liu, Jian, Tan, Lushi, Xu, Yingju, Chen, Qinghao, Liu, Guiquan, Blaustein, Robert O, Johns, Douglas G
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Yu, Wensheng, Liu, Jian, Clausen, Dane, Yu, Younong, Duffy, Joseph L, Wang, Ming, Xu, Shouning, Deng, Lin, Suzuki, Takao, Chung, Christine C, Myers, Robert W, Klein, Daniel J, Fells, James I, Holloway, M. Katharine, Wu, Jin, Wu, Guoxin, Howell, Bonnie J, Barnard, Richard J. O, Kozlowski, Joseph
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Cholesteryl ester transfer protein (CETP) inhibitors based on cyclic urea, bicyclic urea and bicyclic sulfamide cores
Liu, Jian, Shao, Patrick P., Guiadeen, Deodial, Krikorian, Arto, Sun, Wanying, Deng, Qiaolin, Cumiskey, Anne-Marie, Duffy, Ruth A., Murphy, Beth A., Mitra, Kaushik, Johns, Douglas G., Duffy, Joseph L., Vachal, Petr
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Pharmacological Characterization of the Novel and Selective α7 Nicotinic Acetylcholine Receptor-Positive Allosteric Modulator BNC375
Wang, Xiaohai, Daley, Christopher, Gakhar, Vanita, Lange, Henry S, Vardigan, Joshua D, Pearson, Michelle, Zhou, Xiaoping, Warren, Lee, Miller, Corin O, Belden, Michelle, Harvey, Andrew J, Grishin, Anton A, Coles, Carolyn J, O'Connor, Susan M, Thomson, Fiona, Duffy, Joseph L, Bell, Ian M, Uslaner, Jason M
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Published in The Journal of pharmacology and experimental therapeutics (01.05.2020)
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Liu, Jian, Yu, Younong, Kelly, Joseph, Sha, Deyou, Alhassan, Abdul-Basit, Yu, Wensheng, Maletic, Milana M, Duffy, Joseph L, Klein, Daniel J, Holloway, M. Katharine, Carroll, Steve, Howell, Bonnie J, Barnard, Richard J. O, Wolkenberg, Scott, Kozlowski, Joseph A
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Published in ACS medicinal chemistry letters (10.12.2020)
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Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes
Liu, Jian, Guiadeen, Deodial, Krikorian, Arto, Gao, Xiaolei, Wang, James, Babu Boga, Sobhana, Alhassan, Abdul-Basit, Yu, Wensheng, Selyutin, Oleg, Yu, Younong, Anand, Rajan, Xu, Jiayi, Kelly, Joseph, Duffy, Joseph L., Liu, Shilan, Yang, Chundao, Wu, Hao, Cai, Jiaqiang, Bennett, Chad, Maloney, Kevin M., Tyagarajan, Sriram, Gao, Ying-Duo, Fischmann, Thierry O., Presland, Jeremy, Mansueto, My, Xu, Zangwei, Leccese, Erica, Zhang-Hoover, Jie, Knemeyer, Ian, Garlisi, Charles G., Stivers, Peter, Brandish, Philip E., Hicks, Alexandra, Kim, Ronald, Kozlowski, Joseph A.
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Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV‑1 Protein for Clearance
Liu, Jian, Kelly, Joseph, Yu, Wensheng, Clausen, Dane, Yu, Younong, Kim, Hyunjin, Duffy, Joseph L, Chung, Christine C, Myers, Robert W, Carroll, Steve, Klein, Daniel J, Fells, James, Holloway, M. Katharine, Wu, Jin, Wu, Guoxin, Howell, Bonnie J, Barnard, Richard J. O, Kozlowski, Joseph A
Published in ACS medicinal chemistry letters (09.07.2020)
Published in ACS medicinal chemistry letters (09.07.2020)
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