Defining the Molecular Basis for the First Potent and Selective Orthosteric Agonists of the FFA2 Free Fatty Acid Receptor
Hudson, Brian D., Due-Hansen, Maria E., Christiansen, Elisabeth, Hansen, Anna Mette, Mackenzie, Amanda E., Murdoch, Hannah, Pandey, Sunil K., Ward, Richard J., Marquez, Rudi, Tikhonova, Irina G., Ulven, Trond, Milligan, Graeme
Published in The Journal of biological chemistry (14.06.2013)
Published in The Journal of biological chemistry (14.06.2013)
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Reevaluation of Fatty Acid Receptor 1 as a Drug Target for the Stimulation of Insulin Secretion in Humans
WAGNER, Robert, KAISER, Gabriele, FRITSCHE, Andreas, HÄRING, Hans-Ulrich, ULLRICH, Susanne, GERST, Felicia, CHRISTIANSEN, Elisabeth, DUE-HANSEN, Maria E, GRUNDMANN, Manuel, MACHICAO, Fausto, PETER, Andreas, KOSTENIS, Evi, ULVEN, Trond
Published in Diabetes (New York, N.Y.) (01.06.2013)
Published in Diabetes (New York, N.Y.) (01.06.2013)
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A protocol for amide bond formation with electron deficient amines and sterically hindered substrates
Due-Hansen, Maria E., Pandey, Sunil K., Christiansen, Elisabeth, Andersen, Rikke, Hansen, Steffen V. F., Ulven, Trond
Published in Organic & biomolecular chemistry (14.01.2016)
Published in Organic & biomolecular chemistry (14.01.2016)
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Identification of a Potent and Selective Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist with Favorable Physicochemical and in Vitro ADME Properties
Christiansen, Elisabeth, Urban, Christian, Grundmann, Manuel, Due-Hansen, Maria E, Hagesaether, Ellen, Schmidt, Johannes, Pardo, Leonardo, Ullrich, Susanne, Kostenis, Evi, Kassack, Matthias, Ulven, Trond
Published in Journal of medicinal chemistry (13.10.2011)
Published in Journal of medicinal chemistry (13.10.2011)
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Discovery of a Potent and Selective Free Fatty Acid Receptor 1 Agonist with Low Lipophilicity and High Oral Bioavailability
Christiansen, Elisabeth, Due-Hansen, Maria E, Urban, Christian, Grundmann, Manuel, Schmidt, Johannes, Hansen, Steffen V. F, Hudson, Brian D, Zaibi, Mohamed, Markussen, Stine B, Hagesaether, Ellen, Milligan, Graeme, Cawthorne, Michael A, Kostenis, Evi, Kassack, Matthias U, Ulven, Trond
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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Conjugated Linoleic Acids Mediate Insulin Release through Islet G Protein-coupled Receptor FFA1/GPR40
Schmidt, Johannes, Liebscher, Kathrin, Merten, Nicole, Grundmann, Manuel, Mielenz, Manfred, Sauerwein, Helga, Christiansen, Elisabeth, Due-Hansen, Maria E., Ulven, Trond, Ullrich, Susanne, Gomeza, Jesús, Drewke, Christel, Kostenis, Evi
Published in The Journal of biological chemistry (08.04.2011)
Published in The Journal of biological chemistry (08.04.2011)
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Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists: Mesylpropoxy Appendage Lowers Lipophilicity and Improves ADME Properties
Christiansen, Elisabeth, Due-Hansen, Maria E, Urban, Christian, Grundmann, Manuel, Schröder, Ralf, Hudson, Brian D, Milligan, Graeme, Cawthorne, Michael A, Kostenis, Evi, Kassack, Matthias U, Ulven, Trond
Published in Journal of medicinal chemistry (26.07.2012)
Published in Journal of medicinal chemistry (26.07.2012)
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Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy
Hansen, Steffen V. F, Christiansen, Elisabeth, Urban, Christian, Hudson, Brian D, Stocker, Claire J, Due-Hansen, Maria E, Wargent, Ed T, Shimpukade, Bharat, Almeida, Reinaldo, Ejsing, Christer S, Cawthorne, Michael A, Kassack, Matthias U, Milligan, Graeme, Ulven, Trond
Published in Journal of medicinal chemistry (24.03.2016)
Published in Journal of medicinal chemistry (24.03.2016)
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Journal Article
Structure−Activity Study of Dihydrocinnamic Acids and Discovery of the Potent FFA1 (GPR40) Agonist TUG-469
Christiansen, Elisabeth, Due-Hansen, Maria E, Urban, Christian, Merten, Nicole, Pfleiderer, Michael, Karlsen, Kasper K, Rasmussen, Sanne S, Steensgaard, Mette, Hamacher, Alexandra, Schmidt, Johannes, Drewke, Christel, Petersen, Rasmus Koefoed, Kristiansen, Karsten, Ullrich, Susanne, Kostenis, Evi, Kassack, Matthias U, Ulven, Trond
Published in ACS medicinal chemistry letters (14.10.2010)
Published in ACS medicinal chemistry letters (14.10.2010)
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Small-scale fire performance assessment of intumescent coatings on metal tubes containing ammonium nitrate. A stepping-stone towards their application as a fire safety measure on road transportation tanks?
Due-Hansen, Maria E., Johannessen, Tom Cato, Bolsønes, Marianne
Published in Journal of loss prevention in the process industries (01.11.2021)
Published in Journal of loss prevention in the process industries (01.11.2021)
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ChemInform Abstract: A Protocol for Amide Bond Formation with Electron Deficient Amines and Sterically Hindered Substrates
Due‐Hansen, Maria E., Pandey, Sunil K., Christiansen, Elisabeth, Andersen, Rikke, Hansen, Steffen V. F., Ulven, Trond
Published in ChemInform (01.04.2016)
Published in ChemInform (01.04.2016)
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A protocol for amide bond formation with electron deficient amines and sterically hindered substratesElectronic supplementary information (ESI) available: Synthetic procedures, compound characterization, NMR spectra. See DOI: 10.1039/c5ob02129d
Due-Hansen, Maria E, Pandey, Sunil K, Christiansen, Elisabeth, Andersen, Rikke, Hansen, Steffen V. F, Ulven, Trond
Year of Publication 23.12.2015
Year of Publication 23.12.2015
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