Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer
SUN, Jessica D, QIAN LIU, HART, Charles P, JINGLI WANG, AHLUWALIA, Dharmendra, FERRARO, Damien, YAN WANG, DUAN, Jian-Xin, STEVE AMMONS, W, CURD, John G, MATTEUCCI, Mark D
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Published in Clinical cancer research (01.02.2012)
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Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302
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Published in Molecular cancer therapeutics (01.03.2012)
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Characterization of AST‐001 non‐clinical pharmacokinetics: A novel selective AKR1C3‐activated prodrug in mice, rats, and cynomolgus monkeys
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Potent and Highly Selective Hypoxia-Activated Achiral Phosphoramidate Mustards as Anticancer Drugs
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Potent Antitubulin Tumor Cell Cytotoxins Based on 3-Aroyl Indazoles
Duan, Jian-Xin, Cai, Xiaohong, Meng, Fanying, Lan, Leslie, Hart, Charles, Matteucci, Mark
Published in Journal of medicinal chemistry (08.03.2007)
Published in Journal of medicinal chemistry (08.03.2007)
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A Novel and Highly Efficient Synthesis of gem-Difluorocyclopropanes
Tian, Feng, Kruger, Virginie, Bautista, Olivia, Duan, Jian-Xin, Li, An-Rong, Dolbier, William R, Chen, Qing-Yun
Published in Organic letters (24.02.2000)
Published in Organic letters (24.02.2000)
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Efficient synthesis of p-bis-(chlorodifluoromethyl)benzene
Dolbier, William R., Duan, Jian-Xin, Rong, Xiao X.
Published in Journal of fluorine chemistry (01.10.2007)
Published in Journal of fluorine chemistry (01.10.2007)
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Trimethylsilyl fluorosulfonyldifluoroacetate (TFDA): a new, highly efficient difluorocarbene reagent
Dolbier, William R, Tian, Feng, Duan, Jian-Xin, Li, An-Rong, Ait-Mohand, Samia, Bautista, Olivia, Buathong, Saiwan, Marshall Baker, J, Crawford, Jen, Anselme, Pauline, Cai, Xiao Hong, Modzelewska, Aneta, Koroniak, Henryk, Battiste, Merle A, Chen, Qing-Yun
Published in Journal of fluorine chemistry (01.03.2004)
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The Underground Sewer Drainage Design Analysis of Highway Subgrade Under Evaporation
Liu, Jie, Yao, Hai-lin, Lu, Zheng, You, Hui-jie, Duan, Jian-xin
Published in Shanghai jiao tong da xue xue bao (01.06.2013)
Published in Shanghai jiao tong da xue xue bao (01.06.2013)
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TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules
Liu, Qian, Sun, Jessica D., Wang, Jingli, Ahluwalia, Dharmendra, Baker, Amanda F., Cranmer, Lee D., Ferraro, Damien, Wang, Yan, Duan, Jian-Xin, Ammons, W. Steve, Curd, John G., Matteucci, Mark D., Hart, Charles P.
Published in Cancer chemotherapy and pharmacology (01.06.2012)
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14-Aminocamptothecins: Their Synthesis, Preclinical Activity, and Potential Use for Cancer Treatment
Duan, Jian-Xin, Cai, Xiaohong, Meng, Fanying, Sun, Jessica D, Liu, Qian, Jung, Donald, Jiao, Hailong, Matteucci, Jackson, Jung, Brian, Bhupathi, Deepthi, Ahluwalia, Dharmendra, Huang, Heli, Hart, Charles P, Matteucci, Mark
Published in Journal of medicinal chemistry (24.03.2011)
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Pharmacokinetics of TH-302: a hypoxically activated prodrug of bromo-isophosphoramide mustard in mice, rats, dogs and monkeys
Jung, Donald, Lin, Lin, Jiao, Hailong, Cai, Xiaohong, Duan, Jian-Xin, Matteucci, M.
Published in Cancer chemotherapy and pharmacology (01.03.2012)
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Inhibition of Both Thioredoxin Reductase and Glutathione Reductase may Contribute to the Anticancer Mechanism of TH-302
Li, Shengrong, Zhang, Jinsong, Li, Jun, Chen, Dongming, Matteucci, Mark, Curd, John, Duan, Jian-Xin
Published in Biological trace element research (01.09.2010)
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4,5-Dehydrooctafluoro[2.2]paracyclophane: facile generation and extraordinary Diels–Alder reactivity
Battiste, Merle A., Duan, Jian-Xin, Zhai, Yi-An, Ghiviriga, Ion, Abboud, Khalil A., Roitberg, Adrian, Shelton, G.Robert, Dolbier, William R.
Published in Tetrahedron letters (23.09.2002)
Published in Tetrahedron letters (23.09.2002)
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MA JING YUAN, DUAN JIAN-XIN, MARK MATTEUCCI, CAI XIAOHONG, CAO YEYU, JIAO HAILONG
Year of Publication 27.06.2023
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DNA binding ligands targeting drug-resistant Gram-positive bacteria. Part 2: C-terminal benzimidazoles and derivatives
Bürli, Roland W, Jones, Peter, McMinn, Dustin, Le, Quan, Duan, Jian-Xin, Kaizerman, Jacob A, Difuntorum, Stacey, Moser, Heinz E
Published in Bioorganic & medicinal chemistry letters (08.03.2004)
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MA JING YUAN, DUAN JIAN XIN, MATTEUCCI MARK, CAI XIAOHONG, CAO YEYU, JIAO HAILONG
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AZIRIDINE-CONTAINING DNA ALKYLATING AGENT
MA JING YUAN, DUAN JIAN-XIN, MARK MATTEUCCI, CAI XIAOHONG, CAO YEYU, JIAO HAILONG
Year of Publication 17.06.2021
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