Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology
de Boer, Rudolf A., De Keulenaer, Gilles, Bauersachs, Johann, Brutsaert, Dirk, Cleland, John G., Diez, Javier, Du, Xiao‐Jun, Ford, Paul, Heinzel, Frank R., Lipson, Kenneth E., McDonagh, Theresa, Lopez‐Andres, Natalia, Lunde, Ida G., Lyon, Alexander R., Pollesello, Piero, Prasad, Sanjay K., Tocchetti, Carlo G., Mayr, Manuel, Sluijter, Joost P.G., Thum, Thomas, Tschöpe, Carsten, Zannad, Faiez, Zimmermann, Wolfram‐Hubertus, Ruschitzka, Frank, Filippatos, Gerasimos, Lindsey, Merry L., Maack, Christoph, Heymans, Stephane
Published in European journal of heart failure (01.03.2019)
Published in European journal of heart failure (01.03.2019)
Get full text
Journal Article
The actions of relaxin on the human cardiovascular system
Sarwar, Mohsin, Du, Xiao‐Jun, Dschietzig, Thomas B, Summers, Roger J
Published in British journal of pharmacology (01.05.2017)
Published in British journal of pharmacology (01.05.2017)
Get full text
Journal Article
Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease
Kaye, David M, Shihata, Waled A, Jama, Hamdi A, Tsyganov, Kirill, Ziemann, Mark, Kiriazis, Helen, Horlock, Duncan, Vijay, Amrita, Giam, Beverly, Vinh, Antony, Johnson, Chad, Fiedler, April, Donner, Daniel, Snelson, Matthew, Coughlan, Melinda T, Phillips, Sarah, Du, Xiao-Jun, El-Osta, Assam, Drummond, Grant, Lambert, Gavin W, Spector, Tim D, Valdes, Ana M, Mackay, Charles R, Marques, Francine Z
Published in Circulation (New York, N.Y.) (28.04.2020)
Published in Circulation (New York, N.Y.) (28.04.2020)
Get full text
Journal Article
Guidelines for experimental models of myocardial ischemia and infarction
Lindsey, Merry L, Bolli, Roberto, Canty, Jr, John M, Du, Xiao-Jun, Frangogiannis, Nikolaos G, Frantz, Stefan, Gourdie, Robert G, Holmes, Jeffrey W, Jones, Steven P, Kloner, Robert A, Lefer, David J, Liao, Ronglih, Murphy, Elizabeth, Ping, Peipei, Przyklenk, Karin, Recchia, Fabio A, Schwartz Longacre, Lisa, Ripplinger, Crystal M, Van Eyk, Jennifer E, Heusch, Gerd
Published in American journal of physiology. Heart and circulatory physiology (01.04.2018)
Published in American journal of physiology. Heart and circulatory physiology (01.04.2018)
Get full text
Journal Article
β‐Adrenoceptor activation affects galectin‐3 as a biomarker and therapeutic target in heart disease
Du, Xiao‐Jun, Zhao, Wei‐Bo, Nguyen, My‐Nhan, Lu, Qun, Kiriazis, Helen
Published in British journal of pharmacology (01.07.2019)
Published in British journal of pharmacology (01.07.2019)
Get full text
Journal Article
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
Bernardo, Bianca C, Gao, Xiao-Ming, Winbanks, Catherine E, Boey, Esther J. H, Tham, Yow Keat, Kiriazis, Helen, Gregorevic, Paul, Obad, Susanna, Kauppinen, Sakari, Du, Xiao-Jun, Lin, Ruby C. Y, McMullen, Julie R
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2012)
Get full text
Journal Article
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites
Braig, David, Nero, Tracy L., Koch, Hans-Georg, Kaiser, Benedict, Wang, Xiaowei, Thiele, Jan R., Morton, Craig J., Zeller, Johannes, Kiefer, Jurij, Potempa, Lawrence A., Mellett, Natalie A., Miles, Luke A., Du, Xiao-Jun, Meikle, Peter J., Huber-Lang, Markus, Stark, G. Björn, Parker, Michael W., Peter, Karlheinz, Eisenhardt, Steffen U.
Published in Nature communications (23.01.2017)
Published in Nature communications (23.01.2017)
Get full text
Journal Article
Cardiac β‐adrenergic receptor activation mediates distinct and cell type‐dependent changes in the expression and distribution of connexin 43
Zhang, Yi, Hou, Meng‐Chen, Li, Jing‐Jing, Qi, Ying, Zhang, Yu, She, Gang, Ren, Yu‐Jie, Wu, Wei, Pang, Zheng‐Da, Xie, Wenjun, Deng, Xiu‐Ling, Du, Xiao‐Jun
Published in Journal of cellular and molecular medicine (01.08.2020)
Published in Journal of cellular and molecular medicine (01.08.2020)
Get full text
Journal Article
Stimulation of β‐adrenoceptors up‐regulates cardiac expression of galectin‐3 and BIM through the Hippo signalling pathway
Zhao, Wei‐Bo, Lu, Qun, Nguyen, My‐Nhan, Su, Yidan, Ziemann, Mark, Wang, Li‐Na, Kiriazis, Helen, Puthalakath, Hamsa, Sadoshima, Junichi, Hu, Hou‐Yuan, Du, Xiao‐Jun
Published in British journal of pharmacology (01.07.2019)
Published in British journal of pharmacology (01.07.2019)
Get full text
Journal Article
Mechanisms responsible for increased circulating levels of galectin-3 in cardiomyopathy and heart failure
Nguyen, My-Nhan, Su, Yidan, Vizi, Donna, Fang, Lu, Ellims, Andris H., Zhao, Wei-Bo, Kiriazis, Helen, Gao, Xiao-Ming, Sadoshima, Junichi, Taylor, Andrew J., McMullen, Julie R., Dart, Anthony M., Kaye, David M., Du, Xiao-Jun
Published in Scientific reports (29.05.2018)
Published in Scientific reports (29.05.2018)
Get full text
Journal Article
Improving the quality of preclinical research echocardiography: observations, training, and guidelines for measurement
Donner, Daniel G, Kiriazis, Helen, Du, Xiao-Jun, Marwick, Thomas H, McMullen, Julie R
Published in American journal of physiology. Heart and circulatory physiology (01.07.2018)
Published in American journal of physiology. Heart and circulatory physiology (01.07.2018)
Get full text
Journal Article
Hippo pathway activation mediates chemotherapy-induced anti-cancer effect and cardiomyopathy through causing mitochondrial damage and dysfunction
She, Gang, Du, Jin-Chan, Wu, Wei, Pu, Tian-Tian, Zhang, Yu, Bai, Ru-Yue, Zhang, Yi, Pang, Zheng-Da, Wang, Hui-Fang, Ren, Yu-Jie, Sadoshima, Junichi, Deng, Xiu-Ling, Du, Xiao-Jun
Published in Theranostics (2023)
Published in Theranostics (2023)
Get full text
Journal Article
Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice
Qin, Cheng Xue, May, Lauren T., Li, Renming, Cao, Nga, Rosli, Sarah, Deo, Minh, Alexander, Amy E., Horlock, Duncan, Bourke, Jane E., Yang, Yuan H., Stewart, Alastair G., Kaye, David M., Du, Xiao-Jun, Sexton, Patrick M., Christopoulos, Arthur, Gao, Xiao-Ming, Ritchie, Rebecca H.
Published in Nature communications (07.02.2017)
Published in Nature communications (07.02.2017)
Get full text
Journal Article
Chromatin modifications remodel cardiac gene expression
Mathiyalagan, Prabhu, Keating, Samuel T, Du, Xiao-Jun, El-Osta, Assam
Published in Cardiovascular research (01.07.2014)
Published in Cardiovascular research (01.07.2014)
Get full text
Journal Article
HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes
Ooi, Jenny Y Y, Tuano, Natasha K, Rafehi, Haloom, Gao, Xiao-Ming, Ziemann, Mark, Du, Xiao-Jun, El-Osta, Assam
Published in Epigenetics (04.05.2015)
Published in Epigenetics (04.05.2015)
Get full text
Journal Article
Therapeutic silencing of miR-652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy
Bernardo, Bianca C, Nguyen, Sally S, Winbanks, Catherine E, Gao, Xiao-Ming, Boey, Esther J H, Tham, Yow Keat, Kiriazis, Helen, Ooi, Jenny Y Y, Porrello, Enzo R, Igoor, Sindhu, Thomas, Colleen J, Gregorevic, Paul, Lin, Ruby C Y, Du, Xiao-Jun, McMullen, Julie R
Published in The FASEB journal (01.12.2014)
Published in The FASEB journal (01.12.2014)
Get more information
Journal Article
HMGB1 Induces Secretion of Matrix Vesicles by Macrophages to Enhance Ectopic Mineralization
Chen, Qiang, Bei, Jun-Jie, Liu, Chuan, Feng, Shi-Bin, Zhao, Wei-Bo, Zhou, Zhou, Yu, Zheng-Ping, Du, Xiao-Jun, Hu, Hou-Yuan
Published in PloS one (31.05.2016)
Published in PloS one (31.05.2016)
Get full text
Journal Article
Relaxin mitigates microvascular damage and inflammation following cardiac ischemia–reperfusion
Gao, Xiao-Ming, Su, Yidan, Moore, Shirley, Han, Li-Ping, Kiriazis, Helen, Lu, Qun, Zhao, Wei-Bo, Ruze, Amanguli, Fang, Bin-Bin, Duan, Ming-Jun, Du, Xiao-Jun
Published in Basic research in cardiology (01.07.2019)
Published in Basic research in cardiology (01.07.2019)
Get full text
Journal Article
Silencing of miR-34a attenuates cardiac dysfunction in a setting of moderate, but not severe, hypertrophic cardiomyopathy
Bernardo, Bianca C, Gao, Xiao-Ming, Tham, Yow Keat, Kiriazis, Helen, Winbanks, Catherine E, Ooi, Jenny Y Y, Boey, Esther J H, Obad, Susanna, Kauppinen, Sakari, Gregorevic, Paul, Du, Xiao-Jun, Lin, Ruby C Y, McMullen, Julie R
Published in PloS one (27.02.2014)
Published in PloS one (27.02.2014)
Get full text
Journal Article
Activation of Hippo signaling pathway mediates mitochondria dysfunction and dilated cardiomyopathy in mice
Wu, Wei, Ziemann, Mark, Huynh, Kevin, She, Gang, Pang, Zheng-Da, Zhang, Yi, Duong, Thy, Kiriazis, Helen, Pu, Tian-Tian, Bai, Ru-Yue, Li, Jing-Jing, Zhang, Yu, Chen, Ming-Xia, Sadoshima, Junichi, Deng, Xiu-Ling, Meikle, Peter J, Du, Xiao-Jun
Published in Theranostics (01.01.2021)
Published in Theranostics (01.01.2021)
Get full text
Journal Article