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Discovery of genetic biomarkers associated with antituberculosis drug-induced liver injury in the Korean population: Insights from nuclear and mitochondrial DNA variations
Hoa Pham, Thi Vinh, Jang, Tae-Won, Min, Jinsoo, Kim, Jusang, Kim, Hyun-Kuk, Kim, Hye Kyeong, Lee, Jaehee, Lee, Hyun-Kyung, Kim, Dong-Hyun, Cho, Yong-Soon, Kim, Ho-Sook, Shin, Jae-Gook
Published in Drug metabolism and pharmacokinetics (01.06.2025)
Published in Drug metabolism and pharmacokinetics (01.06.2025)
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Translational pharmacokinetic-pharmacodynamic/toxicodynamic (PK-PD/TD) modeling of antitumor effects and peripheral neuropathy in gemcitabine and NAB-paclitaxel chemotherapy
Kobuchi, Shinji, Morita, Atsuko, Jonan, Shizuka, Amagase, Kikuko, Ito, Yukako
Published in Drug metabolism and pharmacokinetics (01.06.2025)
Published in Drug metabolism and pharmacokinetics (01.06.2025)
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Metabolic stability assessment of the tau PET tracer [18F] GTP1
Rich, Sharyl, Wong, Susan, Cheruzel, Lionel, Marik, Jan
Published in Drug metabolism and pharmacokinetics (01.06.2025)
Published in Drug metabolism and pharmacokinetics (01.06.2025)
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CYP7A1 gene induction via SHP-dependent or independent mechanisms can increase the risk of drug-induced liver injury independent or in synergy with BSEP inhibition
Niu, Congrong, Xie, Xiaodong, Liu, Renmeng, Liang, Xiaomin, Hu, Yiding, Lai, Yurong
Published in Drug metabolism and pharmacokinetics (01.06.2025)
Published in Drug metabolism and pharmacokinetics (01.06.2025)
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Enhanced quan/qual approach with software assisted data analysis for tier I soft spot identification in drug discovery
Le, Hoa, Nguyen, Kevin, Jiang, Rencong, Wang, Wei, Geng, Guoju, Murray, Bernard, Yue, Qin
Published in Drug metabolism and pharmacokinetics (01.06.2025)
Published in Drug metabolism and pharmacokinetics (01.06.2025)
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CFT8634, a potent, selective and orally bioavailable BiDACTM degrader of BRD9, highlights the potential of C4T’S TORPEDO® platform to develop degraders with excellent drug-like properties against currently undruggable targets
Chaturvedi, Prasoon, Jackson, Katrina, Agafonov, Roman, He, Minsheng, Nasveschuk, Christopher, Kirby, Jason, Poling, Laura, Pollock, Roy, Hurh, Eunju, Reynolds, Joseph, Reyno, Len, Fisher, Stewart
Published in Drug metabolism and pharmacokinetics (01.06.2025)
Published in Drug metabolism and pharmacokinetics (01.06.2025)
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Implication of H+/peptide transporters (PEPTS) on uptake of N-lactoylphenylalanine (LAC-PHE) in the intestinal and renal epithelial cells
Fujita, Takuya, Nokawa, Miyu, Nonoguchi, Naoko, Nakao, Yuki, Negoro, Ryosuke, Kajimoto, Tetsuya, Abdalkader, Rodi
Published in Drug metabolism and pharmacokinetics (01.06.2025)
Published in Drug metabolism and pharmacokinetics (01.06.2025)
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Effects of phospholipid type and particle size on lipid nanoparticle distribution in vivo and in pancreatic islets
Kanazawa, Takanori, Oguma, Takayuki, Kaneko, Yukiko K., Sato, Ren, Serizawa, Miku, Ooka, Akira, Yamaguchi, Momoka, Ishikawa, Tomohisa, Kondo, Hiromu
Published in Drug metabolism and pharmacokinetics (01.06.2025)
Published in Drug metabolism and pharmacokinetics (01.06.2025)
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