Search Results - "DRUG METABOLISM AND PHARMACOKINETICS" :: K.UTB vyhledávací portál

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Regulation of P-glycoprotein expression and role of ERM proteins in lung cancer cell metastasis

by Liu, Wangyang, Buddhini Perera, Liyanage Manosika, Martha, Larasati, Hariba, Tomoyoshi, Ogihara, Takuo
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Involvement of carrier-mediated transport in ribavirin transport at the blood– testis barrier

by Ito, Takeru, Kubo, Yoshiyuki, Tega, Yuma, Akanuma, Shin-ichi, Hosoya, Ken-ichi
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Developing renal function evaluation for pediatric dose selection based on pharmacometric approach with renally eliminated drugs

by Okada, Akira, Mori, Yuzuki, Saito, Jumpei, Tanzawa, Ayano, Akabane, Miki, Yamatani, Akimasa, Sera, Shoji, Nagai, Naomi
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Quantitative proteomics-based identification of novel thrapeutic targets for progressive supranuclear palsy using post-mortem human brain

by Kumagai, Yuta, Kawami, Masashi, Abe, Yurika, Shimizu, Hiroshi, Nagai, Jun, Ono, Maiko, Takado, Yuhei, Uchida, Yasuo
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Evaluation of acute kidney injury induced by nephrotoxicants using three- dimmensional cultured human proximal tubular epithelial cells

by Arakawa, Hiroshi, Takahashi, Etsushi, Peng, Hanwei, Higuchi, Daichi, Jimbo, Yoichi, Tamai, Ikumi
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Carrier-mediated uptake of capric acid in HEPG2 cells

by Kitamura, Takuma, Yasujima, Tomoya, Yamashiro, Takahiro, Yuasa, Hiroaki
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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In vitro investigation on inhibition potential of deucravacitinib toward human carboxylesterase (CES) 2

by Yao, Ming, Li, Wenying
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Efavirenz-induced heme protein induction and coproporphyrin levels: Insights from in vitro experiments and in vivo studies

by Potzel, Leila, Kinzi, Jonny, Seibert, Isabell, Grube, Markus, Siegmund, Werner, Meyer zu Schwabedissen, Henriette E.
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Thinking beyond cytochrome P450 inactivation kinetics: Enhanced understanding of the mechanism of tucatinib interaction with CYP3A4

by Abdelhamed, Mostafa
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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The regulatory roles of the lncRNA HNF1AOS1 in hepatic drug metabolism in mice

by Armanios, Beshoy
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Food-derived neurotrophic amino acid ergothioneine and its transporter SLC22A4: From bench to healthy food

by Kato, Yukio
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Addressing common metabolism problems in drug discovery with in silico methods

by Barr, Daniel, Öeren, Mario, Hunt, Peter, Tyzack, Jonathan, Walton, Peter, Kaempf, Sylvie, Suri, James, Chrien, Tomas, Mansley, Tamsin, Segall, Matthew
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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A comprehensive platform for evaluating the in vitro CYP reaction phenotyping of New Molecular Entities (NME)

by Jiang, Lifang, Liu, Huan, Tao, Yi, Shen, Liang, Chen, Genfu
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Unraveling the role of HNF1A-AS1 in hepatocyte maturation and subnuclear spaces organization

by Jin, Jing, Armanios, Beshoy, Giang Nguyen, Le Tra, Tawfik, Sherouk, Kolli, Aarush, Zhong, Xiao-bo
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Incorporation of well-stirred, dispersion and parallel tube liver models into simple and permeability limited PBPK frameworks for clearance prediction

by Nagar, Swati, Parise, Rachel, Korzekwa, Ken
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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In vitro assessment of the inhibition of human organic anion transporting polypeptide 1B1/1B3 by highly plasma protein bound compounds in the presence of physiological concentration of albumin

by Zaher, Hani, Kassahun, Kelem, Shi, Qin
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Complex drug-drug interactions: Study design and clinical interpretation

by Vourvahis, Manoli
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Utility of mechanistic static models for predicting CYP- and transporter-mediated DDI

by Peters, Sheila
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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Analysis of drug-endogenous substrate interactions using in vitro and in vivo methods

by Sunakawa, Hiroki, Mizoi, Kenta, Takahashi, Reiko, Hariba, Tomoyoshi, Zuka, Masahiko, Yano, Kentaro, Furumiya, Junichi, Sai, Yoshimichi, Ogihara, Takuo
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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To be there or not to be there: Does presence of human OATP2B1 impact CYP3A expression?

by Schaefer, Anima, Csaba, Anna-Caroline, Padevit, Olivia, Rysz, Marta, Meyer zu Schwabedissen, Henriette
Published in Drug metabolism and pharmacokinetics (01.06.2025)

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