Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma
Verstraete, Kenneth, Peelman, Frank, Braun, Harald, Lopez, Juan, Van Rompaey, Dries, Dansercoer, Ann, Vandenberghe, Isabel, Pauwels, Kris, Tavernier, Jan, Lambrecht, Bart N., Hammad, Hamida, De Winter, Hans, Beyaert, Rudi, Lippens, Guy, Savvides, Savvas N.
Published in Nature communications (03.04.2017)
Published in Nature communications (03.04.2017)
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Journal Article
Efforts towards an On‐Target Version of the Groebke–Blackburn–Bienaymé (GBB) Reaction for Discovery of Druglike Urokinase (uPA) Inhibitors
Gladysz, Rafaela, Vrijdag, Johannes, Van Rompaey, Dries, Lambeir, Anne‐Marie, Augustyns, Koen, De Winter, Hans, Van der Veken, Pieter
Published in Chemistry : a European journal (20.09.2019)
Published in Chemistry : a European journal (20.09.2019)
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Journal Article
Virtual screening for inhibitors of the human TSLP:TSLPR interaction
Van Rompaey, Dries, Verstraete, Kenneth, Peelman, Frank, Savvides, Savvas N., Augustyns, Koen, Van Der Veken, Pieter, De Winter, Hans
Published in Scientific reports (08.12.2017)
Published in Scientific reports (08.12.2017)
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Journal Article
Dataset for quantum-mechanical exploration of conformers and solvent effects in large drug-like molecules
Medrano Sandonas, Leonardo, Van Rompaey, Dries, Fallani, Alessio, Hilfiker, Mathias, Hahn, David, Perez-Benito, Laura, Verhoeven, Jonas, Tresadern, Gary, Kurt Wegner, Joerg, Ceulemans, Hugo, Tkatchenko, Alexandre
Published in Scientific data (07.07.2024)
Published in Scientific data (07.07.2024)
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Journal Article
Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy
Devisscher, Lars, Van Coillie, Samya, Hofmans, Sam, Van Rompaey, Dries, Goossens, Kenneth, Meul, Eline, Maes, Louis, De Winter, Hans, Van Der Veken, Pieter, Vandenabeele, Peter, Berghe, Tom Vanden, Augustyns, Koen
Published in Journal of medicinal chemistry (21.11.2018)
Published in Journal of medicinal chemistry (21.11.2018)
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Journal Article
A Symbolic Regression Model for the Prediction of Drug Binding to Human Liver Microsomes
Van Rompaey, Dries, Morrison, Denise, Van Den Bergh, An, Wegner, Joerg Kurt
Published in Molecular pharmaceutics (01.05.2023)
Published in Molecular pharmaceutics (01.05.2023)
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Journal Article
Tozasertib Analogues as Inhibitors of Necroptotic Cell Death
Hofmans, Sam, Devisscher, Lars, Martens, Sofie, Van Rompaey, Dries, Goossens, Kenneth, Divert, Tatyana, Nerinckx, Wim, Takahashi, Nozomi, De Winter, Hans, Van Der Veken, Pieter, Goossens, Vera, Vandenabeele, Peter, Augustyns, Koen
Published in Journal of medicinal chemistry (08.03.2018)
Published in Journal of medicinal chemistry (08.03.2018)
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Journal Article
Spiro-Azetidine Oxindoles as Long-Acting Injectables for Pre-Exposure Prophylaxis against Respiratory Syncytial Virus Infections
Kesteleyn, Bart, Herschke, Florence, Darville, Nicolas, Stoops, Bart, Jacobs, Tom, Jacoby, Edgar, Shaffer, Paul, Lammens, Lieve, Van Rompaey, Dries, Matcha, Kiran, Martinez Lamenca, Carolina, Coesemans, Erwin, Hache, Geerwin, Pieters, Serge, Lecomte, Morgan, Hu, Lili, Demin, Samuel, Milligan, Cynthia, Abeywickrema, Pravien, De Bruyn, Suzanne, Van Den Berg, Joke, Ysebaert, Nina, De Zwart, Loeckie, Nájera, Isabel, Rigaux, Peter, Roymans, Dirk, Jonckers, Tim H. M.
Published in Journal of medicinal chemistry (11.07.2024)
Published in Journal of medicinal chemistry (11.07.2024)
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Journal Article
On failure modes in molecule generation and optimization
Renz, Philipp, Van Rompaey, Dries, Wegner, Jörg Kurt, Hochreiter, Sepp, Klambauer, Günter
Published in Drug discovery today. Technologies (01.12.2019)
Published in Drug discovery today. Technologies (01.12.2019)
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Journal Article
Novel Small Molecule-Derived, Highly Selective Substrates for Fibroblast Activation Protein (FAP)
De Decker, An, Vliegen, Gwendolyn, Van Rompaey, Dries, Peeraer, Anke, Bracke, An, Verckist, Line, Jansen, Koen, Geiss-Friedlander, Ruth, Augustyns, Koen, De Winter, Hans, De Meester, Ingrid, Lambeir, Anne-Marie, Van der Veken, Pieter
Published in ACS medicinal chemistry letters (08.08.2019)
Published in ACS medicinal chemistry letters (08.08.2019)
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Journal Article
NEW COMPOUNDS
TRESADERN, Gary, VAN OPDENBOSCH, Nina, VAN GOOL, Michiel, VAN ROMPAEY, Dries, LLAVERIA CROS, Josep, OEHLRICH, Daniel, LAMKANFI, Mohamed
Year of Publication 08.06.2023
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Year of Publication 08.06.2023
Patent
NEW COMPOUND
VAN OPDENBOSCH, Nina, TRESADERN, Gary John, VAN ROMPAEY, Dries, LLAVERIA CROS, Josep, OEHLRICH, Daniel, VAN GOOL, Michiel Luc Maria, LAMKANFI, Mohamed
Year of Publication 08.02.2024
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Year of Publication 08.02.2024
Patent
NEW COMPOUNDS
VAN OPDENBOSCH, Nina, VAN GOOL, Michiel, Luc, Maria, TRESADERN, Gary, John, VAN ROMPAEY, Dries, LLAVERIA CROS, Josep, OEHLRICH, Daniel, LAMKANFI, Mohamed
Year of Publication 02.08.2023
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Year of Publication 02.08.2023
Patent
PYRAZOLO[1,5-D][1,2,4]TRIAZINE-5(4H)-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME
VAN OPDENBOSCH, Nina, LLAVERIA CROS, Josep, VAN ROMPAEY, Dries, OEHLRICH, Daniel, VAN GOOL, Michiel Luc Maria, LAMKANFI, Mohamed, MARTINEZ VITURRO, Carlos Manuel
Year of Publication 29.06.2023
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Year of Publication 29.06.2023
Patent
NEW COMPOUNDS
TRESADERN, Gary, VAN OPDENBOSCH, Nina, VAN GOOL, Michiel, VAN ROMPAEY, Dries, LLAVERIA CROS, Josep, OEHLRICH, Daniel, LAMKANFI, Mohamed
Year of Publication 31.03.2022
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Year of Publication 31.03.2022
Patent
PYRAZOLO[1,5-D][1,2,4]TRIAZINE-5(4H)-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY
VAN OPDENBOSCH, Nina, MARTINEZ VITURRO, Carlos, Manuel, VAN GOOL, Michiel, Luc, Maria, LLAVERIA CROS, Josep, VAN ROMPAEY, Dries, OEHLRICH, Daniel, LAMKANFI, Mohamed
Year of Publication 22.02.2023
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Year of Publication 22.02.2023
Patent
4-ALKOXY-6-OXO-PYRIDAZINE DERIVATIVES MODULATING NLRP3
VAN OPDENBOSCH, Nina, VAN GOOL, Michiel, Luc, Maria, MURATORE, Michael, Eric, VAN ROMPAEY, Dries, LINARES DE LA MORENA, Maria, Lourdes, OEHLRICH, Daniel, LAMKANFI, Mohamed, ALCÁZAR VACA, Manuel, Jesús
Year of Publication 10.01.2024
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Year of Publication 10.01.2024
Patent