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Published in Science translational medicine (22.05.2019)
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Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs
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Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice
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Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primates
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Published in Nature communications (04.05.2022)
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Published in PloS one (23.04.2015)
Published in PloS one (23.04.2015)
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BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice
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Published in Blood (23.04.2020)
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Year of Publication 17.08.2021
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Year of Publication 17.08.2021
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Recombinant FVIIIFc-VWF-XTEN Demonstrates Significant Bioavailability Following Subcutaneous Administration in Hemophilia A Mice
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Different Contribution of Hematopoietic and Somatic Cell Types Expressing FcRn to the Prolonged Half-Life of Recombinant Factor VIII Fc and Recombinant FIX Fc
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Published in Blood (16.11.2012)
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FcRn Rescues Recombinant Factor VIII Fc Fusion Protein from a VWF Independent FVIII Clearance Pathway in Mouse Hepatocytes: e0124930
Flier, Arjan vander, Liu, Zhan, Tan, Siyuan, Chen, Kai, Drager, Douglas, Liu, Tongyao, Patarroyo-White, Susannah, Jiang, Haiyan, Light, David R
Published in PloS one (01.04.2015)
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Year of Publication 13.10.2021
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Year of Publication 11.10.2021
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USE OF LENTIVIRAL VECTORS EXPRESSING FACTOR IX
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Year of Publication 29.07.2021
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Use of lentiviral vectors expressing factor IX
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Year of Publication 15.07.2021
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Year of Publication 03.06.2021
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Year of Publication 30.03.2021
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