eTRANSAFE: data science to empower translational safety assessment
Sanz, Ferran, Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Asakura, Shoji, Amberg, Alexander, Bécourt-Lhote, Nathalie, Blomberg, Niklas, Bosc, Nicolas, Briggs, Katharine, Bringezu, Frank, Brulle-Wohlhueter, Claire, Brunak, Søren, Bueters, Ruud, Callegaro, Giulia, Capella-Gutierrez, Salvador, Centeno, Emilio, Corvi, Javier, Cronin, Mark T. D., Drew, Philip, Duchateau-Nguyen, Guillemette, Ecker, Gerhard F., Escher, Sylvia, Felix, Eloy, Ferreiro, Miguel, Frericks, Markus, Furlong, Laura I., Geiger, Robert, George, Catherine, Grandits, Melanie, Ivanov-Draganov, Dragomir, Kilgour-Christie, Jean, Kiziloren, Tevfik, Kors, Jan A., Koyama, Naoki, Kreuchwig, Annika, Leach, Andrew R., Mayer, Miguel-Angel, Monecke, Peter, Muster, Wolfgang, Nakazawa, Chihiro Miyamoto, Nicholson, Gavin, Parry, Rowan, Pastor, Manuel, Piñero, Janet, Oberhauser, Nils, Ramírez-Anguita, Juan Manuel, Rodrigo, Adrián, Smajic, Aljosa, Schaefer, Markus, Schieferdecker, Sebastian, Soininen, Inari, Terricabras, Emma, Trairatphisan, Panuwat, Turner, Sean C., Valencia, Alfonso, van de Water, Bob, van der Lei, Johan L., van Mulligen, Erik M., Vock, Esther, Wilkinson, David
Published in Nature reviews. Drug discovery (01.08.2023)
Published in Nature reviews. Drug discovery (01.08.2023)
Get full text
Journal Article
Dominant Role of Paraoxonases in Inactivation of the Pseudomonas aeruginosa Quorum-Sensing Signal N-(3-Oxododecanoyl)-L-Homoserine Lactone
Teiber, John F, Horke, Sven, Haines, Donovan C, Chowdhary, Puneet K, Xiao, Junhui, Kramer, Gerald L, Haley, Robert W, Draganov, Dragomir I
Published in Infection and Immunity (01.06.2008)
Published in Infection and Immunity (01.06.2008)
Get full text
Journal Article
Preliminary pharmacokinetics of tramadol hydrochloride after administration via different routes in male and female B6 mice
Evangelista Vaz, Rocío, Draganov, Dragomir I., Rapp, Christelle, Avenel, Frederic, Steiner, Guido, Arras, Margarete, Bergadano, Alessandra
Published in Veterinary anaesthesia and analgesia (01.01.2018)
Published in Veterinary anaesthesia and analgesia (01.01.2018)
Get full text
Journal Article
Extensive metabolism and route-dependent pharmacokinetics of bisphenol A (BPA) in neonatal mice following oral or subcutaneous administration
Draganov, Dragomir I, Markham, Dan A, Beyer, Dieter, Waechter, John M, Dimond, Stephen S, Budinsky, Robert A, Shiotsuka, Ronald N, Snyder, Stephanie A, Ehman, Kimberly D, Hentges, Steven G
Published in Toxicology (Amsterdam) (03.07.2015)
Published in Toxicology (Amsterdam) (03.07.2015)
Get full text
Journal Article
Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3
Teiber, John F., Draganov, Dragomir I., Du, Bert N.La
Published in Biochemical pharmacology (15.09.2003)
Published in Biochemical pharmacology (15.09.2003)
Get full text
Journal Article
LTBP2 and CYP1B1 mutations and associated ocular phenotypes in the Roma/Gypsy founder population
AZMANOV, Dimitar N, DIMITROVA, Stanislava, SOODYALL, Himla, CHAKRABARTI, Subhabrata, PADH, Harish, LOPEZ-NEVOT, Miguel A, CHERNODRINSKA, Violeta, ANGUELOV, Botio, MAJUMDER, Partha, ANGELOVA, Lyudmila, KANEVA, Radka, MACKEY, David A, FLOREZ, Laura, TOURNEV, Ivailo, KALAYDJIEVA, Luba, CHERNINKOVA, Sylvia, DRAGANOV, Dragomir, MORAR, Bharti, SAAT, Rosmawati, JUAN, Manel, AROSTEGUI, Juan I, GANGULY, Sriparna
Published in European journal of human genetics : EJHG (01.03.2011)
Published in European journal of human genetics : EJHG (01.03.2011)
Get full text
Journal Article
Mouse Macrophage Paraoxonase 2 Activity Is Increased Whereas Cellular Paraoxonase 3 Activity Is Decreased Under Oxidative Stress
Rosenblat, Mira, Draganov, Dragomir, Watson, Catherine E, Bisgaier, Charles L, La Du, Bert N, Aviram, Michael
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2003)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2003)
Get full text
Journal Article
Estrogen esters as substrates for human paraoxonases
Teiber, John F., Billecke, Scott S., La Du, Bert N., Draganov, Dragomir I.
Published in Archives of biochemistry and biophysics (01.05.2007)
Published in Archives of biochemistry and biophysics (01.05.2007)
Get full text
Journal Article
Apolipoprotein A-I Promotes the Formation of Phosphatidylcholine Core Aldehydes That Are Hydrolyzed by Paraoxonase (PON-1) during High Density Lipoprotein Oxidation with a Peroxynitrite Donor
Ahmed, Z, Ravandi, A, Maguire, G F, Emili, A, Draganov, D, La Du, B N, Kuksis, A, Connelly, P W
Published in The Journal of biological chemistry (06.07.2001)
Published in The Journal of biological chemistry (06.07.2001)
Get full text
Journal Article
The Role of hsp90 in Heme-dependent Activation of Apo-neuronal Nitric-oxide Synthase
Billecke, Scott S, Draganov, Dragomir I, Morishima, Yoshihiro, Murphy, Patrick J M, Dunbar, Anwar Y, Pratt, William B, Osawa, Yoichi
Published in The Journal of biological chemistry (16.07.2004)
Published in The Journal of biological chemistry (16.07.2004)
Get full text
Journal Article
Multiple Substrates for Paraoxonase-1 during Oxidation of Phosphatidylcholine by Peroxynitrite
Ahmed, Zakaria, Ravandi, Amir, Maguire, Graham F., Emili, Andrew, Draganov, Dragomir, La Du, Bert N., Kuksis, Arnis, Connelly, Philip W.
Published in Biochemical and biophysical research communications (11.01.2002)
Published in Biochemical and biophysical research communications (11.01.2002)
Get full text
Journal Article
Rabbit Serum Paraoxonase 3 (PON3) Is a High Density Lipoprotein-associated Lactonase and Protects Low Density Lipoprotein against Oxidation
Draganov, Dragomir I., Stetson, Philip L., Watson, Catherine E., Billecke, Scott S., La Du, Bert N.
Published in The Journal of biological chemistry (27.10.2000)
Published in The Journal of biological chemistry (27.10.2000)
Get full text
Journal Article
Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity
Connelly, Philip W., Maguire, Graham F., Draganov, Dragomir I.
Published in Journal of lipid research (01.03.2004)
Published in Journal of lipid research (01.03.2004)
Get full text
Journal Article
Perspectives of data science in preclinical safety assessment
Steger-Hartmann, Thomas, Kreuchwig, Annika, Wang, Ken, Birzele, Fabian, Draganov, Dragomir, Gaudio, Stefano, Rothfuss, Andreas
Published in Drug discovery today (01.08.2023)
Published in Drug discovery today (01.08.2023)
Get full text
Journal Article