ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type
Schifanella, Luca, Barnett, Susan W, Bissa, Massimiliano, Galli, Veronica, Doster, Melvin N, Vaccari, Monica, Tomaras, Georgia D, Shen, Xiaoying, Phogat, Sanjay, Pal, Ranajit, Montefiori, David C, LaBranche, Celia C, Rao, Mangala, Trinh, Hung V, Washington-Parks, Robyn, Liyanage, Namal P M, Gorini, Giacomo, Brown, Dallas R, Liang, Frank, Loré, Karin, Venzon, David J, Magnanelli, William, Metrinko, Michelle, Kramer, Josh, Breed, Matthew, Alter, Galit, Ruprecht, Ruth M, Franchini, Genoveffa
Published in PLoS pathogens (01.12.2019)
Published in PLoS pathogens (01.12.2019)
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Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate
Vaccari, Monica, Fourati, Slim, Brown, Dallas R, Silva de Castro, Isabela, Bissa, Massimiliano, Schifanella, Luca, Doster, Melvin N, Foulds, Kathryn E, Roederer, Mario, Koup, Richard A, Sui, Yongjun, Berzofsky, Jay A, Sekaly, Rafick-Pierre, Franchini, Genoveffa
Published in Frontiers in immunology (14.05.2019)
Published in Frontiers in immunology (14.05.2019)
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Protection Afforded by an HIV Vaccine Candidate in Macaques Depends on the Dose of SIVmac251 at Challenge Exposure
Vaccari, Monica, Keele, Brandon F, Bosinger, Steven E, Doster, Melvin N, Ma, Zhong-Min, Pollara, Justin, Hryniewicz, Anna, Ferrari, Guido, Guan, Yongjun, Forthal, Donald N, Venzon, David, Fenizia, Claudio, Morgan, Tia, Montefiori, David, Lifson, Jeffrey D, Miller, Chris J, Silvestri, Guido, Rosati, Margherita, Felber, Barbara K, Pavlakis, George N, Tartaglia, James, Franchini, Genoveffa
Published in Journal of Virology (01.03.2013)
Published in Journal of Virology (01.03.2013)
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In Vivo Treatment with Insulin-like Growth Factor 1 Reduces CCR5 Expression on Vaccine-Induced Activated CD4 + T-Cells
Bissa, Massimiliano, Galli, Veronica, Schifanella, Luca, Vaccari, Monica, Rahman, Mohammad Arif, Gorini, Giacomo, Binello, Nicolò, Sarkis, Sarkis, Gutowska, Anna, Silva de Castro, Isabela, Doster, Melvin N, Moles, Ramona, Ferrari, Guido, Shen, Xiaoying, Tomaras, Georgia D, Montefiori, David C, N'guessan, Kombo F, Paquin-Proulx, Dominic, Kozlowski, Pamela A, Venzon, David J, Choo-Wosoba, Hyoyoung, Breed, Matthew W, Kramer, Joshua, Franchini, Genoveffa
Published in Vaccines (Basel) (30.10.2023)
Published in Vaccines (Basel) (30.10.2023)
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Fatal Pancreatitis in Simian Immunodeficiency Virus SIVmac251-Infected Macaques Treated with 2′,3′-Dideoxyinosine and Stavudine following Cytotoxic-T-Lymphocyte-Associated Antigen 4 and Indoleamine 2,3-Dioxygenase Blockade
VACCARI, Monica, BOASSO, Adriano, FRANCHINI, Genoveffa, FENIZIA, Claudio, FUCHS, Dietmar, HRYNIEWICZ, Anna, MORGAN, Tia, WEISS, Deborah, DOSTER, Melvin N, HERAUD, Jean Michel, SHEARER, Gene M
Published in Journal of Virology (01.01.2012)
Published in Journal of Virology (01.01.2012)
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Transient Viral Activation in Human T Cell Leukemia Virus Type 1-Infected Macaques Treated With Pomalidomide
Gutowska, Anna, McKinnon, Katherine, Sarkis, Sarkis, Doster, Melvin N, Bissa, Massimiliano, Moles, Ramona, Stamos, James D, Rahman, Mohammad Arif, Washington-Parks, Robyn, Davis, David, Yarchoan, Robert, Franchini, Genoveffa, Pise-Masison, Cynthia A
Published in Frontiers in medicine (05.05.2022)
Published in Frontiers in medicine (05.05.2022)
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HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition
Vaccari, Monica, Fourati, Slim, Gordon, Shari N., Brown, Dallas R., Bissa, Massimilano, Schifanella, Luca, Silva de Castro, Isabela, Doster, Melvin N., Galli, Veronica, Omsland, Maria, Fujikawa, Dai, Gorini, Giacomo, Liyanage, Namal P. M., Trinh, Hung V., McKinnon, Katherine M., Foulds, Kathryn E., Keele, Brandon F., Roederer, Mario, Koup, Richard A., Shen, Xiaoying, Tomaras, Georgia D., Wong, Marcus P., Munoz, Karissa J., Gach, Johannes S., Forthal, Donald N., Montefiori, David C., Venzon, David J., Felber, Barbara K., Rosati, Margherita, Pavlakis, George N., Rao, Mangala, Sekaly, Rafick-Pierre, Franchini, Genoveffa
Published in Nature medicine (01.06.2018)
Published in Nature medicine (01.06.2018)
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HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC
Bissa, Massimiliano, Kim, Sohyoung, Galli, Veronica, Fourati, Slim, Sarkis, Sarkis, Arakelyan, Anush, de Castro, Isabela Silva, Rahman, Mohammad Arif, Fujiwara, Saori, Vaccari, Monica, Tomalka, Jeffrey A., Stamos, James D., Schifanella, Luca, Gorini, Giacomo, Moles, Ramona, Gutowska, Anna, Ferrari, Guido, Lobanov, Alexei, Montefiori, David C., Nelson, George W., Cam, Margaret C., Chakhtoura, Marita, Haddad, Elias K., Doster, Melvin N., McKinnon, Katherine, Brown, Sophia, Venzon, David J., Choo-Wosoba, Hyoyoung, Breed, Matthew W., Killoran, Kristin E., Kramer, Joshua, Margolis, Leonid, Sekaly, Rafick P., Hager, Gordon L., Franchini, Genoveffa
Published in Nature communications (02.02.2023)
Published in Nature communications (02.02.2023)
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Loss of HIV candidate vaccine efficacy in male macaques by mucosal nanoparticle immunization rescued by V2-specific response
Rahman, Mohammad Arif, Bissa, Massimiliano, Scinto, Hanna, Howe, Savannah E., Sarkis, Sarkis, Ma, Zhong-Min, Gutowska, Anna, Jiang, Xunqing, Luo, Christina C., Schifanella, Luca, Moles, Ramona, Silva de Castro, Isabela, Basu, Shraddha, N’guessan, Kombo F., Williams, LaTonya D., Becerra-Flores, Manuel, Doster, Melvin N., Hoang, Tanya, Choo-Wosoba, Hyoyoung, Woode, Emmanuel, Sui, Yongjun, Tomaras, Georgia D., Paquin-Proulx, Dominic, Rao, Mangala, Talton, James D., Kong, Xiang-Peng, Zolla-Pazner, Susan, Cardozo, Timothy, Franchini, Genoveffa, Berzofsky, Jay A.
Published in Nature communications (22.10.2024)
Published in Nature communications (22.10.2024)
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Expression of CD40L by the ALVAC-Simian Immunodeficiency Virus Vector Abrogates T Cell Responses in Macaques
Silva de Castro, Isabela, Gordon, Shari N, Liu, Jun, Bissa, Massimiliano, McKinnon, Katherine, Trinh, Hung V, Doster, Melvin N, Schifanella, Luca, Liyanage, Namal P, Cao, JinChao, Cheng, Olivia, Foulds, Kathryn, Roederer, Mario, Koup, Richard A, Shen, Xiaoying, Tomaras, Georgia D, Venzon, David J, Forthal, Donald N, Fouts, Timothy, Montefiori, David C, Tartaglia, Jim, Rao, Mangala, Ostrowski, Mario, Franchini, Genoveffa, Vaccari, Monica
Published in Journal of virology (28.02.2020)
Published in Journal of virology (28.02.2020)
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Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIVmac251 Acquisition
Gordon, Shari N, Liyanage, Namal P M, Doster, Melvin N, Vaccari, Monica, Vargas-Inchaustegui, Diego A, Pegu, Poonam, Schifanella, Luca, Shen, Xiaoying, Tomaras, Georgia D, Rao, Mangala, Billings, Erik A, Schwartz, Jennifer, Prado, Ilia, Bobb, Kathryn, Zhang, Wenlei, Montefiori, David C, Foulds, Kathryn E, Ferrari, Guido, Robert-Guroff, Marjorie, Roederer, Mario, Phan, Tran B, Forthal, Donald N, Stablein, Donald M, Phogat, Sanjay, Venzon, David J, Fouts, Timothy, Franchini, Genoveffa
Published in The Journal of immunology (1950) (01.10.2016)
Published in The Journal of immunology (1950) (01.10.2016)
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Cutting edge: novel vaccination modality provides significant protection against mucosal infection by highly pathogenic simian immunodeficiency virus
Strbo, Natasa, Vaccari, Monica, Pahwa, Savita, Kolber, Michael A, Doster, Melvin N, Fisher, Eva, Gonzalez, Louis, Stablein, Donald, Franchini, Genoveffa, Podack, Eckhard R
Published in The Journal of immunology (1950) (15.03.2013)
Published in The Journal of immunology (1950) (15.03.2013)
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Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia
Gordon, Shari N, Doster, Melvin N, Kines, Rhonda C, Keele, Brandon F, Brocca-Cofano, Egidio, Guan, Yongjun, Pegu, Poonam, Liyanage, Namal P M, Vaccari, Monica, Cuburu, Nicolas, Buck, Christopher B, Ferrari, Guido, Montefiori, David, Piatak, Jr, Michael, Lifson, Jeffrey D, Xenophontos, Anastasia M, Venzon, David, Robert-Guroff, Marjorie, Graham, Barney S, Lowy, Douglas R, Schiller, John T, Franchini, Genoveffa
Published in The Journal of immunology (1950) (15.12.2014)
Published in The Journal of immunology (1950) (15.12.2014)
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Publisher Correction: Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques
Rahman, Mohammad Arif, Bissa, Massimiliano, Silva de Castro, Isabela, Helmold Hait, Sabrina, Stamos, James D., Bhuyan, Farzana, Hunegnaw, Ruth, Sarkis, Sarkis, Gutowska, Anna, Doster, Melvin N., Moles, Ramona, Hoang, Tanya, Miller Jenkins, Lisa M., Appella, Ettore, Venzon, David J., Choo-Wosoba, Hyoyoung, Cardozo, Timothy, Baum, Marc M., Appella, Daniel H., Robert-Guroff, Marjorie, Franchini, Genoveffa
Published in Nature microbiology (01.08.2023)
Published in Nature microbiology (01.08.2023)
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Antiretroviral therapy partly reverses the systemic and mucosal distribution of NK cell subsets that is altered by SIVmac251 infection of macaques
Liyanage, Namal P.M, Gordon, Shari N, Doster, Melvin N, Pegu, Poonam, Vaccari, Monica, Shukur, Nebiyu, Schifanella, Luca, Pise-Masison, Cynthia A, Lipinska, Danuta, Grubczak, Kamil, Moniuszko, Marcin, Franchini, Genoveffa
Published in Virology (New York, N.Y.) (01.02.2014)
Published in Virology (New York, N.Y.) (01.02.2014)
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Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques
Rahman, Mohammad Arif, Bissa, Massimiliano, Silva de Castro, Isabela, Helmold Hait, Sabrina, Stamos, James D., Bhuyan, Farzana, Hunegnaw, Ruth, Sarkis, Sarkis, Gutowska, Anna, Doster, Melvin N., Moles, Ramona, Hoang, Tanya, Miller Jenkins, Lisa M., Appella, Ettore, Venzon, David J., Choo-Wosoba, Hyoyoung, Cardozo, Timothy, Baum, Marc M., Appella, Daniel H., Robert-Guroff, Marjorie, Franchini, Genoveffa
Published in Nature microbiology (01.05.2023)
Published in Nature microbiology (01.05.2023)
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Glucocorticoid treatment at moderate doses of SIVmac251-infected rhesus macaques decreases the frequency of circulating CD14+CD16++ monocytes but does not alter the tissue virus reservoir
Moniuszko, Marcin, Liyanage, Namal P M, Doster, Melvin N, Parks, Robyn Washington, Grubczak, Kamil, Lipinska, Danuta, McKinnon, Katherine, Brown, Charles, Hirsch, Vanessa, Vaccari, Monica, Gordon, Shari, Pegu, Poonam, Fenizia, Claudio, Flisiak, Robert, Grzeszczuk, Anna, Dabrowska, Milena, Robert-Guroff, Marjorie, Silvestri, Guido, Stevenson, Mario, McCune, Joseph, Franchini, Genoveffa
Published in AIDS research and human retroviruses (01.01.2015)
Published in AIDS research and human retroviruses (01.01.2015)
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Transient increase of interferon-stimulated genes and no clinical benefit by chloroquine treatment during acute simian immunodeficiency virus infection of macaques
Vaccari, Monica, Fenizia, Claudio, Ma, Zhong-Min, Hryniewicz, Anna, Boasso, Adriano, Doster, Melvin N, Miller, Christopher J, Lindegardh, Niklas, Tarning, Joel, Landay, Alan L, Shearer, Gene M, Franchini, Genoveffa
Published in AIDS research and human retroviruses (01.04.2014)
Published in AIDS research and human retroviruses (01.04.2014)
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Journal Article
Gp96 SIVIg immunization induces potent polyepitope specific, multifunctional memory responses in rectal and vaginal mucosa
Strbo, Natasa, Vaccari, Monica, Pahwa, Savita, Kolber, Michael A., Fisher, Eva, Gonzalez, Louis, Doster, Melvin N., Hryniewicz, Anna, Felber, Barbara K., Pavlakis, George N., Franchini, Genoveffa, Podack, Eckhard R.
Published in Vaccine (21.03.2011)
Published in Vaccine (21.03.2011)
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Gp96SᴵⱽIg immunization induces potent polyepitope specific, multifunctional memory responses in rectal and vaginal mucosa
Strbo, Natasa, Vaccari, Monica, Pahwa, Savita, Kolber, Michael A, Fisher, Eva, Gonzalez, Louis, Doster, Melvin N, Hryniewicz, Anna, Felber, Barbara K, Pavlakis, George N, Franchini, Genoveffa, Podack, Eckhard R
Published in Vaccine (21.03.2011)
Published in Vaccine (21.03.2011)
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