Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors
Ho, Ming-Chih David, Ring, Nicholas, Amaral, Kirsten, Doshi, Utkarsh, Li, Albert P
Published in Drug metabolism and disposition (01.06.2017)
Published in Drug metabolism and disposition (01.06.2017)
Get full text
Journal Article
In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries
Utkarsh, Doshi, Loretz, Carol, Li, Albert P.
Published in Chemico-biological interactions (05.08.2016)
Published in Chemico-biological interactions (05.08.2016)
Get full text
Journal Article
Prediction of the Pharmacokinetics of Pravastatin as an OATP Substrate Using Plateable Human Hepatocytes With Human Plasma Data and PBPK Modeling
Mao, Jialin, Doshi, Utkarsh, Wright, Matthew, Hop, Cornelis E. C. A., Li, Albert P., Chen, Yuan
Published in CPT: pharmacometrics and systems pharmacology (01.04.2018)
Published in CPT: pharmacometrics and systems pharmacology (01.04.2018)
Get full text
Journal Article
Effects of culture duration on gene expression of P450 isoforms, uptake and efflux transporters in primary hepatocytes cultured in the absence and presence of interleukin-6: implications for experimental design for the evaluation of downregulatory effects of biotherapeutics
Yang, Qian, Doshi, Utkarsh, Li, Nicole, Li, Albert P
Published in Current drug metabolism (01.09.2012)
Published in Current drug metabolism (01.09.2012)
Get more information
Journal Article
Utility of pooled cryopreserved human enterocytes as an in vitro model for assessing intestinal clearance and drug–drug interactions
Wong, Susan, Doshi, Utkarsh, Vuong, Peter, Liu, Ning, Tay, Suzanne, Le, Hoa, Kenny, Jane, Li, Albert P., Yan, Zhengyin
Published in Drug metabolism and pharmacokinetics (01.01.2018)
Published in Drug metabolism and pharmacokinetics (01.01.2018)
Get full text
Journal Article
Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions
Wong, Susan, Doshi, Utkarsh, Vuong, Peter, Liu, Ning, Tay, Suzanne, Le, Hoa, Kosaka, Mika, Kenny, Jane R, Li, Albert P, Yan, Zhengyin
Published in Drug metabolism letters (2018)
Published in Drug metabolism letters (2018)
Get more information
Journal Article
Synthesis and anticonvulsant activity of new N-1′,N-3′-disubstituted-2′H,3H,5′H-spiro-(2-benzofuran-1,4′-imidazolidine)-2′,3,5′-triones
Patel, Hardik J., Sarra, Joe, Caruso, Francesco, Rossi, Miriam, Doshi, Utkarsh, Stephani, Ralph A.
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Get full text
Journal Article
Endoplasmic Reticulum Stress Induction and ERK1/2 Activation Contribute to Nefazodone-Induced Toxicity in Hepatic Cells
Ren, Zhen, Chen, Si, Zhang, Jie, Doshi, Utkarsh, Li, Albert P, Guo, Lei
Published in Toxicological sciences (01.12.2016)
Published in Toxicological sciences (01.12.2016)
Get full text
Journal Article
Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles
Zhang, Jie, Doshi, Utkarsh, Suzuki, Ayako, Chang, Ching-Wei, Borlak, Jürgen, Li, Albert P., Tong, Weida
Published in Chemico-biological interactions (05.08.2016)
Published in Chemico-biological interactions (05.08.2016)
Get full text
Journal Article
A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment
Iskandar, Anita R., Zanetti, Filippo, Kondylis, Athanasios, Martin, Florian, Leroy, Patrice, Majeed, Shoaib, Steiner, Sandro, Xiang, Yang, Ortega Torres, Laura, Trivedi, Keyur, Guedj, Emmanuel, Merg, Celine, Frentzel, Stefan, Ivanov, Nikolai V., Doshi, Utkarsh, Lee, Kyeonghee Monica, McKinney, Willie J., Peitsch, Manuel C., Hoeng, Julia
Published in Internal and emergency medicine (01.09.2019)
Published in Internal and emergency medicine (01.09.2019)
Get full text
Journal Article
Synthesis and anticonvulsant activity of new N-1',N-3'-disubstituted-2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-triones
Patel, Hardik J, Sarra, Joe, Caruso, Francesco, Rossi, Miriam, Doshi, Utkarsh, Stephani, Ralph A
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Get full text
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Journal Article
Synthesis and anticonvulsant activity of new N-1',N-3'-disubstituted- 2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-trio nes
Patel, Hardik J, Sarra, Joe, Caruso, Francesco, Rossi, Miriam, Doshi, Utkarsh, Stephani, Ralph A
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Get full text
Journal Article
Synthesis and anticonvulsant activity of new N-1',N-31-disubstituted-2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-triones
PATEL, Hardik J, SARRA, Joe, CARUSO, Francesco, ROSSI, Miriam, DOSHI, Utkarsh, STEPHANI, Ralph A
Published in Bioorganic & medicinal chemistry letters (2006)
Get full text
Published in Bioorganic & medicinal chemistry letters (2006)
Journal Article
Synthesis and anticonvulsant activity of new N-1′,N-3′-disubstituted-2′ H,3 H,5′ H-spiro-(2-benzofuran-1,4′-imidazolidine)-2′,3,5′-triones
Patel, Hardik J., Sarra, Joe, Caruso, Francesco, Rossi, Miriam, Doshi, Utkarsh, Stephani, Ralph A.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
Get full text
Journal Article