Structure Property Relationships of Carboxylic Acid Isosteres
Lassalas, Pierrik, Gay, Bryant, Lasfargeas, Caroline, James, Michael J, Tran, Van, Vijayendran, Krishna G, Brunden, Kurt R, Kozlowski, Marisa C, Thomas, Craig J, Smith, Amos B, Huryn, Donna M, Ballatore, Carlo
Published in Journal of medicinal chemistry (14.04.2016)
Published in Journal of medicinal chemistry (14.04.2016)
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Journal Article
Microtubule Stabilizing Agents as Potential Treatment for Alzheimer’s Disease and Related Neurodegenerative Tauopathies
Ballatore, Carlo, Brunden, Kurt R, Huryn, Donna M, Trojanowski, John Q, Lee, Virginia M.-Y, Smith, Amos B
Published in Journal of medicinal chemistry (08.11.2012)
Published in Journal of medicinal chemistry (08.11.2012)
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Journal Article
Contributions of academic laboratories to the discovery and development of chemical biology tools
Huryn, Donna M, Resnick, Lynn O, Wipf, Peter
Published in Journal of medicinal chemistry (26.09.2013)
Published in Journal of medicinal chemistry (26.09.2013)
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Journal Article
PTPRT epigenetic silencing defines lung cancer with STAT3 activation and can direct STAT3 targeted therapies
Sen, Malabika, Kindsfather, Audrey, Danilova, Ludmila, Zhang, Feng, Colombo, Raffaele, LaPorte, Matthew G., Kurland, Brenda F., Huryn, Donna M., Wipf, Peter, Herman, James G.
Published in Epigenetics (02.07.2020)
Published in Epigenetics (02.07.2020)
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Journal Article
Identification of novel inhibitors of dietary lipid absorption using zebrafish
Clifton, Justin D, Lucumi, Edinson, Myers, Michael C, Napper, Andrew, Hama, Kotaro, Farber, Steven A, Smith, 3rd, Amos B, Huryn, Donna M, Diamond, Scott L, Pack, Michael
Published in PloS one (25.08.2010)
Published in PloS one (25.08.2010)
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Journal Article
Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum
Chiang, Annette N., Valderramos, Juan-Carlos, Balachandran, Raghavan, Chovatiya, Raj J., Mead, Brian P., Schneider, Corinne, Bell, Samantha L., Klein, Michael G., Huryn, Donna M., Chen, Xiaojiang S., Day, Billy W., Fidock, David A., Wipf, Peter, Brodsky, Jeffrey L.
Published in Bioorganic & medicinal chemistry (15.02.2009)
Published in Bioorganic & medicinal chemistry (15.02.2009)
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Journal Article
Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back
Cantor, Elinor H., Faul, Margaret M., Huryn, Donna M., Kallander, Lara, Ruck, Rebecca T., Watson, Mary P.
Published in ACS central science (25.10.2023)
Published in ACS central science (25.10.2023)
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Journal Article
Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators
Huryn, Donna M, Brodsky, Jeffrey L, Brummond, Kay M, Chambers, Peter G, Eyer, Benjamin, Ireland, Alex W, Kawasumi, Masaoki, LaPorte, Matthew G, Lloyd, Kayla, Manteau, Baptiste, Nghiem, Paul, Quade, Bettina, Seguin, Sandlin P, Wipf, Peter
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2011)
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Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors
Nandi, Purbasha, DeVore, Kira, Wang, Feng, Li, Shan, Walker, Joel D., Truong, Thanh Tung, LaPorte, Matthew G., Wipf, Peter, Schlager, Heidi, McCleerey, John, Paquette, William, Columbres, Rod Carlo A., Gan, Taiping, Poh, Yu-Ping, Fromme, Petra, Flint, Andrew J., Wolf, Mark, Huryn, Donna M., Chou, Tsui-Fen, Chiu, Po-Lin
Published in Communications chemistry (09.08.2024)
Published in Communications chemistry (09.08.2024)
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Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells
Johnston, Paul A, Nguyen, Minh M, Dar, Javid A, Ai, Junkui, Wang, Yujuan, Masoodi, Khalid Z, Shun, Tongying, Shinde, Sunita, Camarco, Daniel P, Hua, Yun, Huryn, Donna M, Wilson, Gabriela Mustata, Lazo, John S, Nelson, Joel B, Wipf, Peter, Wang, Zhou
Published in Assay and drug development technologies (01.05.2016)
Published in Assay and drug development technologies (01.05.2016)
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Cyclopentane-1,3-dione: A Novel Isostere for the Carboxylic Acid Functional Group. Application to the Design of Potent Thromboxane (A2) Receptor Antagonists
Ballatore, Carlo, Soper, James H, Piscitelli, Francesco, James, Michael, Huang, Longchuan, Atasoylu, Onur, Huryn, Donna M, Trojanowski, John Q, Lee, Virginia M.-Y, Brunden, Kurt R, Smith, Amos B
Published in Journal of medicinal chemistry (13.10.2011)
Published in Journal of medicinal chemistry (13.10.2011)
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Journal Article
p97: An Emerging Target for Cancer, Neurodegenerative Diseases, and Viral Infections
Huryn, Donna M, Kornfilt, David J. P, Wipf, Peter
Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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Journal Article
Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway
Alverez, Celeste, Bulfer, Stacie L, Chakrasali, Ramappa, Chimenti, Michael. S, Deshaies, Raymond J, Green, Neal, Kelly, Mark, LaPorte, Matthew G, Lewis, Taber S, Liang, Mary, Moore, William J, Neitz, R. Jeffrey, Peshkov, Vsevolod A, Walters, Michael A, Zhang, Feng, Arkin, Michelle R, Wipf, Peter, Huryn, Donna M
Published in ACS medicinal chemistry letters (11.02.2016)
Published in ACS medicinal chemistry letters (11.02.2016)
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Journal Article
Ferroptosis as a Novel Therapeutic Target for Friedreich's Ataxia
Cotticelli, M Grazia, Xia, Shujuan, Lin, Daniel, Lee, Taehee, Terrab, Leila, Wipf, Peter, Huryn, Donna M, Wilson, Robert B
Published in The Journal of pharmacology and experimental therapeutics (01.04.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2019)
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Journal Article
Replacement of the hydroxamic acid group in the selective HDAC8 inhibitor PCI-34051
Long, Keith, Close, David A., Johnston, Paul A., Huryn, Donna M.
Published in Bioorganic & medicinal chemistry letters (01.08.2024)
Published in Bioorganic & medicinal chemistry letters (01.08.2024)
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Journal Article
Kinetic Characterization and Molecular Docking of a Novel, Potent, and Selective Slow-Binding Inhibitor of Human Cathepsin L
Shah, Parag P, Myers, Michael C, Beavers, Mary Pat, Purvis, Jeremy E, Jing, Huiyan, Grieser, Heather J, Sharlow, Elizabeth R, Napper, Andrew D, Huryn, Donna M, Cooperman, Barry S, Smith, 3rd, Amos B, Diamond, Scott L
Published in Molecular pharmacology (01.07.2008)
Published in Molecular pharmacology (01.07.2008)
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HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus
Johnston, Paul A, Phillips, Jennifer, Shun, Tong Ying, Shinde, Sunita, Lazo, John S, Huryn, Donna M, Myers, Michael C, Ratnikov, Boris I, Smith, Jeffrey W, Su, Ying, Dahl, Russell, Cosford, Nicholas D P, Shiryaev, Sergey A, Strongin, Alex Y
Published in Assay and drug development technologies (01.12.2007)
Published in Assay and drug development technologies (01.12.2007)
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Journal Article
Medicinal Chemistry: Where Are All the Women?
Huryn, Donna M, Bolognesi, Maria Laura, Young, Wendy B
Published in ACS medicinal chemistry letters (14.09.2017)
Published in ACS medicinal chemistry letters (14.09.2017)
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