Search Results - "DONGHI MONICA" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

by Summa, Vincenzo, Petrocchi, Alessia, Bonelli, Fabio, Crescenzi, Benedetta, Donghi, Monica, Ferrara, Marco, Fiore, Fabrizio, Gardelli, Cristina, Gonzalez Paz, Odalys, Hazuda, Daria J, Jones, Philip, Kinzel, Olaf, Laufer, Ralph, Monteagudo, Edith, Muraglia, Ester, Nizi, Emanuela, Orvieto, Federica, Pace, Paola, Pescatore, Giovanna, Scarpelli, Rita, Stillmock, Kara, Witmer, Marc V, Rowley, Michael
Published in Journal of medicinal chemistry (25.09.2008)

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Journal Article

Patent Strategy in Pharmaceutical industry : Are Additional Patents Valuable? (Edition 1)

Patent Strategy in Pharmaceutical industry : Are Additional Patents Valuable? (Edition 1)

by Donghi, Monica
Year of Publication 2014

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eBook

A Combinatorial Approach to Polyketide-Type Libraries by Iterative Asymmetric Aldol Reactions Performed on Solid Support

A Combinatorial Approach to Polyketide-Type Libraries by Iterative Asymmetric Aldol Reactions Performed on Solid Support

by Paterson, Ian, Donghi, Monica, Gerlach, Kai
Published in Angewandte Chemie International Edition (15.09.2000)

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Journal Article

Synthesis of a hexahydropyrimido[1,2- a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor

Synthesis of a hexahydropyrimido[1,2- a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor

by Ferrara, Marco, Crescenzi, Benedetta, Donghi, Monica, Muraglia, Ester, Nizi, Emanuela, Pesci, Silvia, Summa, Vincenzo, Gardelli, Cristina
Published in Tetrahedron letters (19.11.2007)

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Journal Article

3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates-A new class of HIV-1 integrase inhibitors

3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates-A new class of HIV-1 integrase inhibitors

by DONGHI, Monica, KINZEL, Olaf D, SUMMA, Vincenzo
Published in Bioorganic & medicinal chemistry letters (01.04.2009)

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Journal Article

Taxol Semisynthesis: A Highly Enantio- and Diastereoselective Synthesis of the Side Chain and a New Method for Ester Formation at C-13 Using Thioesters

Taxol Semisynthesis: A Highly Enantio- and Diastereoselective Synthesis of the Side Chain and a New Method for Ester Formation at C-13 Using Thioesters

by Gennari, Cesare, Carcano, Michela, Donghi, Monica, Mongelli, Nicola, Vanotti, Ermes, Vulpetti, Anna
Published in Journal of organic chemistry (11.07.1997)

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Journal Article

3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates--a new class of HIV-1 integrase inhibitors

3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates--a new class of HIV-1 integrase inhibitors

by Donghi, Monica, Kinzel, Olaf D, Summa, Vincenzo
Published in Bioorganic & medicinal chemistry letters (01.04.2009)

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Journal Article

Phosphoramidate Prodrugs of 2′-C-Methylcytidine for Therapy of Hepatitis C Virus Infection

Phosphoramidate Prodrugs of 2′-C-Methylcytidine for Therapy of Hepatitis C Virus Infection

by Gardelli, Cristina, Attenni, Barbara, Donghi, Monica, Meppen, Malte, Pacini, Barbara, Harper, Steven, Di Marco, Annalise, Fiore, Fabrizio, Giuliano, Claudio, Pucci, Vincenzo, Laufer, Ralph, Gennari, Nadia, Marcucci, Isabella, Leone, Joseph F, Olsen, David B, MacCoss, Malcolm, Rowley, Michael, Narjes, Frank
Published in Journal of medicinal chemistry (10.09.2009)

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Journal Article

3-Hydroxy-4-oxo-4 H-pyrido[1,2- a]pyrimidine-2-carboxylates—A new class of HIV-1 integrase inhibitors

3-Hydroxy-4-oxo-4 H-pyrido[1,2- a]pyrimidine-2-carboxylates—A new class of HIV-1 integrase inhibitors

by Donghi, Monica, Kinzel, Olaf D., Summa, Vincenzo
Published in Bioorganic & medicinal chemistry letters (2009)

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Journal Article

Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-based design and synthesis of new templates

Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-based design and synthesis of new templates

by Malancona, Savina, Donghi, Monica, Ferrara, Marco, Martin Hernando, Josè I., Pompei, Marco, Pesci, Silvia, Ontoria, Jesus M., Koch, Uwe, Rowley, Michael, Summa, Vincenzo
Published in Bioorganic & medicinal chemistry (15.04.2010)

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Journal Article

Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors

Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors

by Muraglia, Ester, Kinzel, Olaf, Gardelli, Cristina, Crescenzi, Benedetta, Donghi, Monica, Ferrara, Marco, Nizi, Emanuela, Orvieto, Federica, Pescatore, Giovanna, Laufer, Ralph, Gonzalez-Paz, Odalys, Di Marco, Annalise, Fiore, Fabrizio, Monteagudo, Edith, Fonsi, Massimiliano, Felock, Peter J, Rowley, Michael, Summa, Vincenzo
Published in Journal of medicinal chemistry (28.02.2008)

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Journal Article

Synthesis and evaluation of novel phosphoramidate prodrugs of 2′-methyl cytidine as inhibitors of hepatitis c virus NS5B polymerase

Synthesis and evaluation of novel phosphoramidate prodrugs of 2′-methyl cytidine as inhibitors of hepatitis c virus NS5B polymerase

by Donghi, Monica, Attenni, Barbara, Gardelli, Cristina, Marco, Annalise Di, Fiore, Fabrizio, Giuliano, Claudio, Laufer, Ralph, Leone, Joseph F., Pucci, Vincenzo, Rowley, Michael, Narjes, Frank
Published in Bioorganic & medicinal chemistry letters (01.03.2009)

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Journal Article

Regioselective Synthesis of 7,8-Dihydropyrrolo[1,2-a]pyrimidin-4(6H)-ones and 7,8-Dihydropyrrolo[1,2-a]pyrimidin-2(6H)-ones

Regioselective Synthesis of 7,8-Dihydropyrrolo[1,2-a]pyrimidin-4(6H)-ones and 7,8-Dihydropyrrolo[1,2-a]pyrimidin-2(6H)-ones

by Donghi, Monica, Pesci, Silvia, Summa, Vincenzo, Koch, Uwe, Spieser, Stephane, Gardelli, Cristina
Published in Synlett (01.01.2010)

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Journal Article

3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates-fast access to a heterocyclic scaffold for HIV-1 integrase inhibitors

3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates-fast access to a heterocyclic scaffold for HIV-1 integrase inhibitors

by Kinzel, Olaf D., Ball, Richard G., Donghi, Monica, Maguire, Courtney K., Muraglia, Ester, Pesci, Silvia, Rowley, Michael, Summa, Vincenzo
Published in Tetrahedron letters (10.11.2008)

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Journal Article

Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-Amino Acid N-Terminus: Discovery and Optimization of a New Series of P2−P4 Macrocycles

Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-Amino Acid N-Terminus: Discovery and Optimization of a New Series of P2−P4 Macrocycles

by Harper, Steven, Ferrara, Marco, Crescenzi, Benedetta, Pompei, Marco, Palumbi, Maria Cecilia, DiMuzio, Jillian M, Donghi, Monica, Fiore, Fabrizio, Koch, Uwe, Liverton, Nigel J, Pesci, Silvia, Petrocchi, Alessia, Rowley, Michael, Summa, Vincenzo, Gardelli, Cristina
Published in Journal of medicinal chemistry (13.08.2009)

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Journal Article

3-Hydroxy-4-oxo-4 H-pyrido[1,2- a]pyrimidine-2-carboxylates—fast access to a heterocyclic scaffold for HIV-1 integrase inhibitors

3-Hydroxy-4-oxo-4 H-pyrido[1,2- a]pyrimidine-2-carboxylates—fast access to a heterocyclic scaffold for HIV-1 integrase inhibitors

by Kinzel, Olaf D., Ball, Richard G., Donghi, Monica, Maguire, Courtney K., Muraglia, Ester, Pesci, Silvia, Rowley, Michael, Summa, Vincenzo
Published in Tetrahedron letters (2008)

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Journal Article

Structure-based design of amidinophenylurea-derivatives for factor VIIa inhibition

Structure-based design of amidinophenylurea-derivatives for factor VIIa inhibition

by KLINGLER, Otmar, MATTER, Hans, SCHUDOK, Manfred, DONGHI, Monica, CZECH, Joerg, LORENZ, Martin, NESTLER, Hans Peter, SZILLAT, Hauke, SCHREUDER, Herman
Published in Bioorganic & medicinal chemistry letters (16.07.2004)

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Journal Article

France

France

by Donghi, Monica
Published in Patent Strategy in Pharmaceutical Industry: Are additional patents valuable? (17.02.2014)

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Book Chapter

2. Patent Portfolio

2. Patent Portfolio

by Donghi, Monica
Published in Patent Strategy in Pharmaceutical Industry: Are additional patents valuable? (17.02.2014)

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Book Chapter

C. Generic Drugs Approval

C. Generic Drugs Approval

by Donghi, Monica
Published in Patent Strategy in Pharmaceutical Industry: Are additional patents valuable? (17.02.2014)

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Book Chapter

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