Nonclinical Safety Evaluation of Muraglitazar, a Novel PPARα/γ Agonist
Waites, Crystal R., Dominick, Mark A., Sanderson, Thomas P., Schilling, Beth E.
Published in Toxicological sciences (01.11.2007)
Published in Toxicological sciences (01.11.2007)
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Rodent Carcinogenicity Profile of the Antidiabetic Dual PPAR α and γ Agonist Muraglitazar
Tannehill-Gregg, Sarah H., Sanderson, Thomas P., Minnema, Daniel, Voelker, Richard, Ulland, Borge, Cohen, Samuel M., Arnold, Lora L., Schilling, Beth E., Waites, C. Robbie, Dominick, Mark A.
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Published in Toxicological sciences (01.07.2007)
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Urothelial carcinogenesis in the urinary bladder of male rats treated with muraglitazar, a PPAR alpha/gamma agonist: Evidence for urolithiasis as the inciting event in the mode of action
Dominick, Mark A, White, Melvin R, Sanderson, Thomas P, Van Vleet, Terry, Cohen, Samuel M, Arnold, Lora E, Cano, Marty, Tannehill-Gregg, Sarah, Moehlenkamp, Jeffrey D, Waites, Crystal R, Schilling, Beth E
Published in Toxicologic pathology (01.01.2006)
Published in Toxicologic pathology (01.01.2006)
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Strain-related differences in urine composition of male rats of potential relevance to urolithiasis
Tannehill-Gregg, Sarah H, Dominick, Mark A, Reisinger, Amy J, Moehlenkamp, Jeffrey D, Waites, C Robbie, Stock, David A, Sanderson, Thomas P, Cohen, Samuel M, Arnold, Lora L, Schilling, Beth E
Published in Toxicologic pathology (01.04.2009)
Published in Toxicologic pathology (01.04.2009)
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Subchronic Urinary Bladder Effects of Muraglitazar in Male Rats
Van Vleet, Terry R., White, M. Randy, Sanderson, Thomas P., Cohen, Samuel M., Cano, Martin, Arnold, Lora L., Waites, C. Robbie, Schilling, Beth E., Mitroka, James, Dominick, Mark A.
Published in Toxicological sciences (01.03.2007)
Published in Toxicological sciences (01.03.2007)
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Urine acidification has no effect on peroxisome proliferator-activated receptor (PPAR) signaling or epidermal growth factor (EGF) expression in rat urinary bladder urothelium
Achanzar, William E., Moyer, Carolyn F., Marthaler, Laura T., Gullo, Russell, Chen, Shen-Jue, French, Michele H., Watson, Linda M., Rhodes, James W., Kozlosky, John C., White, Melvin R., Foster, William R., Burgun, James J., Car, Bruce D., Cosma, Gregory N., Dominick, Mark A.
Published in Toxicology and applied pharmacology (15.09.2007)
Published in Toxicology and applied pharmacology (15.09.2007)
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Dietary ammonium chloride for the acidification of mouse urine
Reisinger, Amy J, Tannehill-Gregg, Sarah H, Waites, C. Robbie, Dominick, Mark A, Schilling, Beth E, Jackson, Todd A
Published in Journal of the American Association for Laboratory Animal Science (01.03.2009)
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Published in Journal of the American Association for Laboratory Animal Science (01.03.2009)
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Heterocyclic Ureas: Inhibitors of Acyl-CoA:Cholesterol O-Acyltransferase as Hypocholesterolemic Agents
White, Andrew D, Creswell, Mark W, Chucholowski, Alexander W, Blankley, C. John, Wilson, Michael W, Bousley, Richard F, Essenburg, Arnold D, Hamelehle, Katherine L, Krause, Brian R, Stanfield, Richard L, Dominick, Mark A, Neub, Martin
Published in Journal of medicinal chemistry (25.10.1996)
Published in Journal of medicinal chemistry (25.10.1996)
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Subchronic Urinary Bladder Effects of Muraglitazar in Male Rats1
Van Vleet, Terry R., White, M. Randy, Sanderson, Thomas P., Cohen, Samuel M., Cano, Martin, Arnold, Lora L., Waites, C. Robbie, Schilling, Beth E., Mitroka, James, Dominick, Mark A.
Published in Toxicological sciences (01.03.2007)
Published in Toxicological sciences (01.03.2007)
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An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines
Sistare, Frank D, Morton, Daniel, Alden, Carl, Christensen, Joel, Keller, Douglas, Jonghe, Sandra De, Storer, Richard D, Reddy, M Vijayaraj, Kraynak, Andrew, Trela, Bruce, Bienvenu, Jean-Guy, Bjurström, Sivert, Bosmans, Vanessa, Brewster, David, Colman, Karyn, Dominick, Mark, Evans, John, Hailey, James R, Kinter, Lewis, Liu, Matt, Mahrt, Charles, Marien, Dirk, Myer, James, Perry, Richard, Potenta, Daniel, Roth, Arthur, Sherratt, Philip, Singer, Thomas, Slim, Rabih, Soper, Keith, Fransson-Steen, Ronny, Stoltz, James, Turner, Oliver, Turnquist, Susan, van Heerden, Marjolein, Woicke, Jochen, DeGeorge, Joseph J
Published in Toxicologic pathology (01.06.2011)
Published in Toxicologic pathology (01.06.2011)
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Toxicologic effects of a novel acyl-CoA:cholesterol acyltransferase inhibitor in cynomolgus monkeys
Reindel, J F, Dominick, M A, Bocan, T M, Gough, A W, McGuire, E J
Published in Toxicologic pathology (01.09.1994)
Published in Toxicologic pathology (01.09.1994)
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Journal Article
Nonclinical safety evaluation of muraglitazar, a novel PPARalpha/gamma agonist
Waites, Crystal R, Dominick, Mark A, Sanderson, Thomas P, Schilling, Beth E
Published in Toxicological sciences (01.11.2007)
Get full text
Published in Toxicological sciences (01.11.2007)
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Proliferative bone lesions in rats given anticancer compounds
Courtney, C L, Kim, S N, Walsh, K M, Watkins, J R, Dominick, M A
Published in Toxicologic pathology (01.01.1991)
Published in Toxicologic pathology (01.01.1991)
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