Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo
Schofield, Darren J., Irving, Lorraine, Calo, Laura, Bogstedt, Anna, Rees, Gareth, Nuccitelli, Annalisa, Narwal, Rajesh, Petrone, Marcella, Roberts, Jennifer, Brown, Lee, Cusdin, Fiona, Dosanjh, Bhupinder, Lloyd, Christopher, Dobson, Claire, Gurrell, Ian, Fraser, Graham, McFarlane, Mary, Rockenstein, Edward, Spencer, Brian, Masliah, Eliezer, Spillantini, Maria Grazia, Tan, Keith, Billinton, Andrew, Vaughan, Tris, Chessell, Iain, Perkinton, Michael S.
Published in Neurobiology of disease (01.12.2019)
Published in Neurobiology of disease (01.12.2019)
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Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain
Williams, Wendy A, Linley, John E, Jones, Clare A, Shibata, Yoko, Snijder, Arjan, Button, James, Hatcher, Jon P, Huang, Ling, Taddese, Bruck, Thornton, Peter, Schofield, Darren J, Thom, George, Popovic, Bojana, Dosanjh, Bhupinder, Wilkinson, Trevor, Hughes, Jane, Dobson, Claire L, Groves, Maria A, Webster, Carl I, Billinton, Andy, Vaughan, Tristan J, Chessell, Iain
Published in Pain (Amsterdam) (01.09.2019)
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A direct role for SNX9 in the biogenesis of filopodia
Jarsch, Iris K, Gadsby, Jonathan R, Nuccitelli, Annalisa, Mason, Julia, Shimo, Hanae, Pilloux, Ludovic, Marzook, Bishara, Mulvey, Claire M, Dobramysl, Ulrich, Bradshaw, Charles R, Lilley, Kathryn S, Hayward, Richard D, Vaughan, Tristan J, Dobson, Claire L, Gallop, Jennifer L
Published in The Journal of cell biology (06.04.2020)
Published in The Journal of cell biology (06.04.2020)
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Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry
Yin, Victor, Devine, Paul W. A, Saunders, Janet C, Barendregt, Arjan, Cusdin, Fiona, Ristani, Alexandra, Hines, Alistair, Shepherd, Sam, Dembek, Marcin, Dobson, Claire L, Snijder, Joost, Bond, Nicholas J, Heck, Albert J. R
Published in Chemical science (Cambridge) (13.09.2023)
Published in Chemical science (Cambridge) (13.09.2023)
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Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo
Dobson, Claire L, Devine, Paul W A, Phillips, Jonathan J, Higazi, Daniel R, Lloyd, Christopher, Popovic, Bojana, Arnold, Joanne, Buchanan, Andrew, Lewis, Arthur, Goodman, Joanne, van der Walle, Christopher F, Thornton, Peter, Vinall, Lisa, Lowne, David, Aagaard, Anna, Olsson, Lise-Lotte, Ridderstad Wollberg, Anna, Welsh, Fraser, Karamanos, Theodoros K, Pashley, Clare L, Iadanza, Matthew G, Ranson, Neil A, Ashcroft, Alison E, Kippen, Alistair D, Vaughan, Tristan J, Radford, Sheena E, Lowe, David C
Published in Scientific reports (20.12.2016)
Published in Scientific reports (20.12.2016)
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Chemically Defined, High-Density Insect Cell-Based Expression System for Scalable AAV Vector Production
Kurasawa, James H., Park, Andrew, Sowers, Carrie R., Halpin, Rebecca A., Tovchigrechko, Andrey, Dobson, Claire L., Schmelzer, Albert E., Gao, Changshou, Wilson, Susan D., Ikeda, Yasuhiro
Published in Molecular therapy. Methods & clinical development (11.12.2020)
Published in Molecular therapy. Methods & clinical development (11.12.2020)
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Isolation of high-affinity, neutralizing anti-idiotype antibodies by phage and ribosome display for application in immunogenicity and pharmacokinetic analyses
Chin, Stacey E., Ferraro, Franco, Groves, Maria, Liang, Meina, Vaughan, Tristan J., Dobson, Claire L.
Published in Journal of immunological methods (01.01.2015)
Published in Journal of immunological methods (01.01.2015)
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Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancer
Schofield, Darren J, Percival-Alwyn, Jennifer, Rytelewski, Mateusz, Hood, John, Rothstein, Raymond, Wetzel, Leslie, McGlinchey, Kelly, Adjei, Grace, Watkins, Amanda, Machiesky, LeeAnn, Chen, Weimin, Andrews, John, Groves, Maria, Morrow, Michelle, Stewart, Ross A, Leinster, Andrew, Wilkinson, Robert W, Hammond, Scott A, Luheshi, Nadia, Dobson, Claire, Oberst, Michael
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma
Cohen, E Suzanne, Dobson, Claire L, Käck, Helena, Wang, Bing, Sims, Dorothy A, Lloyd, Christopher O, England, Elizabeth, Rees, D Gareth, Guo, Hongwei, Karagiannis, Sophia N, O'Brien, Siobhan, Persdotter, Sofia, Ekdahl, Helena, Butler, Robin, Keyes, Feenagh, Oakley, Sarah, Carlsson, Mats, Briend, Emmanuel, Wilkinson, Trevor, Anderson, Ian K, Monk, Phillip D, von Wachenfeldt, Karin, Eriksson, Per-Olof F, Gould, Hannah J, Vaughan, Tristan J, May, Richard D
Published in mAbs (01.05.2014)
Published in mAbs (01.05.2014)
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Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism
Dobson, Claire L., Main, Sarah, Newton, Philip, Chodorge, Matthieu, Cadwallader, Karen, Humphreys, Robin C., Albert, Vivian, Vaughan, Tristan J., Minter, Ralph R., Edwards, Bryan M.
Published in mAbs (01.11.2009)
Published in mAbs (01.11.2009)
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Juvenile Violent Victimization and Adult Criminal Outcomes: The Role of Military Service as a Turning Point in Young Adulthood
Orak, Ugur, Soileau, Christine, Harter, Jessica, Dobson, Claire, Huey Dye, Meredith
Published in Journal of interpersonal violence (01.04.2024)
Published in Journal of interpersonal violence (01.04.2024)
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Abstract 1828: AZD8853: A novel antibody targeting GDF15 for immunotherapy refractory tumors
Hurt, Elaine, Thomas, Suneetha, Mulgrew, Kathy, Blackmore, Stephen, Moynihan, James, Cusdin, Fiona, Dodd, Roger, Cariuk, Peter, Sigurdardottir, Anna, Brannigan, Emily, Dobson, Claire, Kumar, Rakesh, Cobbold, Mark
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine
Kopruszinski, Caroline M, Thornton, Peter, Arnold, Joanne, Newton, Philip, Lowne, David, Navratilova, Edita, Swiokla, Juliana, Dodick, David W, Dobson, Claire, Gurrell, Ian, Chessell, Iain Patrick, Porreca, Frank
Published in Cephalalgia (01.12.2020)
Published in Cephalalgia (01.12.2020)
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Autoantibodies are associated with disease progression in idiopathic pulmonary fibrosis
Koether, Katerina, Besnard, Valérie, Sandig, Hilary, Carruthers, Alan, Miranda, Elena, Grootenboer-Mignot, Sabine, Taillé, Camille, Chevret, Sylvie, Valeyre, Dominique, Nunes, Hilario, Israel-Biet, Dominique, Lim, Wei Keat, Cottin, Vincent, Corkill, Dominic, Dobson, Claire, Groves, Maria, Ferraro, Franco, Guenzi, Edouard, Huang, Ling, Sulikowski, Michal, Mailleux, Arnaud, Murray, Lynne Anne, Mustelin, Thomas, Strickland, Ian, Sleeman, Matthew A, Crestani, Bruno
Published in The European respiratory journal (01.05.2023)
Published in The European respiratory journal (01.05.2023)
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Assessment of AAV9 distribution and transduction in rats after administration through Intrastriatal, Intracisterna magna and Lumbar Intrathecal routes
Chandran, Jayanth, Chowdhury, Ekram Ahmed, Perkinton, Michael, Jamier, Tanguy, Sutton, Daniel, Wu, Shengjia, Dobson, Claire, Shah, Dhaval K, Chessell, Iain, Meno-Tetang, Guy M L
Published in Gene therapy (01.02.2023)
Published in Gene therapy (01.02.2023)
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Generation and characterization of LymphoStat‐B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator
Baker, Kevin P., Edwards, Bryan M., Main, Sarah H., Choi, Gil H., Wager, Ruth E., Halpern, Wendy G., Lappin, Patrick B., Riccobene, Todd, Abramian, Donara, Sekut, Les, Sturm, Bonnie, Poortman, Carol, Minter, Ralph R., Dobson, Claire L., Williams, Elizabeth, Carmen, Sara, Smith, Rodger, Roschke, Viktor, Hilbert, David M., Vaughan, Tristan J., Albert, Vivian R.
Published in Arthritis and rheumatism (01.11.2003)
Published in Arthritis and rheumatism (01.11.2003)
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Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors
Colley, Caroline S, Popovic, Bojana, Sridharan, Sudharsan, Debreczeni, Judit E, Hargeaves, David, Fung, Michael, An, Ling-Ling, Edwards, Bryan, Arnold, Joanne, England, Elizabeth, Eghobamien, Laura, Sivars, Ulf, Flavell, Liz, Renshaw, Jonathan, Wickson, Kate, Warrener, Paul, Zha, Jingying, Bonnell, Jessica, Woods, Rob, Wilkinson, Trevor, Dobson, Claire, Vaughan, Tristan J
Published in mAbs (01.01.2018)
Published in mAbs (01.01.2018)
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BISPECIFIC BINDING PROTEINS AND USES THEREOF
SEAMAN JONATHAN, POLLIZZI KRISTEN, GAO CHANGSHOU, KASTURIRANGAN SRINATH, MAZOR YARIV, DRABIC STACEY, OBERST MICHAEL, HERBST RONALD, DOBSON CLAIRE LOUISE, SCHOFIELD DARREN, HAMMOND SCOTT A, DOVEDI SIMON, LOBO BRIAN, RAINEY GODFREY, MORROW MICHELLE, CARLESSO GIANLUCA, MANIKWAR PRAKASH
Year of Publication 26.06.2024
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Year of Publication 26.06.2024
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