Search Results - "DOBROWSKY RICK T" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism

The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism

by Qian, Pengxu, He, Xi C., Paulson, Ariel, Li, Zhenrui, Tao, Fang, Perry, John M., Guo, Fengli, Zhao, Meng, Zhi, Lei, Venkatraman, Aparna, Haug, Jeffrey S., Parmely, Tari, Li, Hua, Dobrowsky, Rick T., Ding, Wen-Xing, Kono, Tomohiro, Ferguson-Smith, Anne C., Li, Linheng
Published in Cell stem cell (04.02.2016)

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Journal Article

A Role for Ceramide, but Not Diacylglycerol, in the Antagonism of Insulin Signal Transduction by Saturated Fatty Acids

A Role for Ceramide, but Not Diacylglycerol, in the Antagonism of Insulin Signal Transduction by Saturated Fatty Acids

by Chavez, Jose Antonio, Knotts, Trina A, Wang, Li-Ping, Li, Guibin, Dobrowsky, Rick T, Florant, Gregory L, Summers, Scott A
Published in The Journal of biological chemistry (21.03.2003)

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Journal Article

Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes

Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes

by Chowdhury, Subir K Roy, Dobrowsky, Rick T, Fernyhough, Paul
Published in Mitochondrion (01.11.2011)

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Journal Article

C-Terminal Heat Shock Protein 90 Inhibitor Decreases Hyperglycemia-induced Oxidative Stress and Improves Mitochondrial Bioenergetics in Sensory Neurons

C-Terminal Heat Shock Protein 90 Inhibitor Decreases Hyperglycemia-induced Oxidative Stress and Improves Mitochondrial Bioenergetics in Sensory Neurons

by Zhang, Liang, Zhao, Huiping, Blagg, Brian S. J, Dobrowsky, Rick T
Published in Journal of proteome research (06.04.2012)

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Journal Article

Ceramide displaces cholesterol from lipid rafts and decreases the association of the cholesterol binding protein caveolin-1

Ceramide displaces cholesterol from lipid rafts and decreases the association of the cholesterol binding protein caveolin-1

by Yu, Cuijuan, Alterman, Michail, Dobrowsky, Rick T
Published in Journal of lipid research (01.08.2005)

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Journal Article

Caveolin-1 and Altered Neuregulin Signaling Contribute to the Pathophysiological Progression of Diabetic Peripheral Neuropathy

Caveolin-1 and Altered Neuregulin Signaling Contribute to the Pathophysiological Progression of Diabetic Peripheral Neuropathy

by MCGUIRE, James F, ROUEN, Shefali, SIEGFREID, Eric, WRIGHT, Douglas E, DOBROWSKY, Rick T
Published in Diabetes (New York, N.Y.) (01.11.2009)

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Journal Article

Hyperglycemia Alters the Schwann Cell Mitochondrial Proteome and Decreases Coupled Respiration in the Absence of Superoxide Production

Hyperglycemia Alters the Schwann Cell Mitochondrial Proteome and Decreases Coupled Respiration in the Absence of Superoxide Production

by Zhang, Liang, Yu, Cuijuan, Vasquez, Francisco E, Galeva, Nadya, Onyango, Isaac, Swerdlow, Russell H, Dobrowsky, Rick T
Published in Journal of proteome research (01.01.2010)

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Journal Article

Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice

Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice

by Urban, Michael J, Li, Chengyuan, Yu, Cuijuan, Lu, Yuanming, Krise, Joanna M, McIntosh, Michelle P, Rajewski, Roger A, Blagg, Brian S J, Dobrowsky, Rick T
Published in ASN neuro (11.08.2010)

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Journal Article

Induction of heat shock protein 70 (Hsp70) prevents neuregulin-induced demyelination by enhancing the proteasomal clearance of c-Jun

Induction of heat shock protein 70 (Hsp70) prevents neuregulin-induced demyelination by enhancing the proteasomal clearance of c-Jun

by Li, Chengyuan, Ma, Jiacheng, Zhao, Huiping, Blagg, Brian S J, Dobrowsky, Rick T
Published in ASN neuro (06.12.2012)

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Journal Article

Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis

Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis

by ILSLEY, Jillian N. M, NAKANISHI, Masako, FLYNN, Christopher, BELINSKY, Glenn S, DE GUISE, Sylvain, ADIB, John N, DOBROWSKY, Rick T, BONVENTRE, Joseph V, ROSENBERG, Daniel W
Published in Cancer research (Chicago, Ill.) (01.04.2005)

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Journal Article

Targeting the Diabetic Chaperome to Improve Peripheral Neuropathy

Targeting the Diabetic Chaperome to Improve Peripheral Neuropathy

by Dobrowsky, Rick T.
Published in Current Diabetes Reports (01.08.2016)

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Journal Article Book Review

Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach?

Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach?

by Farmer, Kevin L, Li, Chengyuan, Dobrowsky, Rick T
Published in Pharmacological reviews (01.10.2012)

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Journal Article

Synthesis and evaluation of 3′- and 4′-substituted cyclohexyl noviomimetics that modulate mitochondrial respiration

Synthesis and evaluation of 3′- and 4′-substituted cyclohexyl noviomimetics that modulate mitochondrial respiration

by Meka, Penchala Narasimharao, Amatya, Eva, Kaur, Sukhmanjit, Banerjee, Monimoy, Zuo, Ang, Dobrowsky, Rick T., Blagg, Brian S.J.
Published in Bioorganic & medicinal chemistry (15.09.2022)

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Journal Article

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

by Dobrowsky, Rick T., Werner, Mark H., Castellino, Alexander M., Chao, Moses V., Hannun, Yusuf A.
Published in Science (American Association for the Advancement of Science) (09.09.1994)

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Journal Article

Altered Neurotrophism in Diabetic Neuropathy: Spelunking the Caves of Peripheral Nerve

Altered Neurotrophism in Diabetic Neuropathy: Spelunking the Caves of Peripheral Nerve

by Dobrowsky, Rick T, Rouen, Shefali, Yu, Cuijuan
Published in The Journal of pharmacology and experimental therapeutics (01.05.2005)

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Journal Article

Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

by AKUDE, Eli, ZHEREBITSKAYA, Elena, CHOWDHURY, Subir K. Roy, SMITH, Darrell R, DOBROWSKY, Rick T, FERNYHOUGH, Paul
Published in Diabetes (New York, N.Y.) (01.01.2011)

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Journal Article

KU-596 decreases mitochondrial superoxide and improves bioenergetics following downregulation of manganese superoxide dismutase in diabetic sensory neurons

KU-596 decreases mitochondrial superoxide and improves bioenergetics following downregulation of manganese superoxide dismutase in diabetic sensory neurons

by You, Zhenyuan, Zhang, Zheng, Blagg, Brian S.J., Dobrowsky, Rick T.
Published in Experimental neurology (01.03.2019)

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Journal Article

Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following KU-32 therapy

Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following KU-32 therapy

by Ma, Jiacheng, Farmer, Kevin L, Pan, Pan, Urban, Michael J, Zhao, Huiping, Blagg, Brian S J, Dobrowsky, Rick T
Published in The Journal of pharmacology and experimental therapeutics (01.02.2014)

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Journal Article

Synthesis and evaluation of a ring-constrained Hsp90 C-terminal inhibitor that exhibits neuroprotective activity

Synthesis and evaluation of a ring-constrained Hsp90 C-terminal inhibitor that exhibits neuroprotective activity

by Zhang, Zheng, You, Zhenyuan, Dobrowsky, Rick T., Blagg, Brian S.J.
Published in Bioorganic & medicinal chemistry letters (01.09.2018)

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Journal Article

Endoplasmic Reticulum-resident Heat Shock Protein 90 (HSP90) Isoform Glucose-regulated Protein 94 (GRP94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport

Endoplasmic Reticulum-resident Heat Shock Protein 90 (HSP90) Isoform Glucose-regulated Protein 94 (GRP94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport

by Ghosh, Suman, Shinogle, Heather E., Galeva, Nadezhda A., Dobrowsky, Rick T., Blagg, Brian S.J.
Published in The Journal of biological chemistry (15.04.2016)

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